A5073834124- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Infective Endocarditis Diagnosis and Management
- Aortic aneurysm repair treatments
- Peripheral Artery Disease Management
- Pulmonary Hypertension Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Salivary Gland Disorders and Functions
- Mechanical Circulatory Support Devices
- Gastrointestinal motility and disorders
- Vascular Anomalies and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
St. Antonius Ziekenhuis
2016-2025
University Medical Center Utrecht
2003-2015
Koninklijke Landmacht
2013
Deventer Ziekenhuis
2011
Meander Medisch Centrum
2011
Royal Brompton Hospital
2011
Imperial College London
2011
Universitat de Barcelona
2011
Utrecht University
2008
Park Terrace Care Center
2006
Context High on-treatment platelet reactivity is associated with atherothrombotic events following coronary stent implantation. Objective To evaluate the capability of multiple function tests to predict clinical outcome. Design, Setting, and Patients Prospective, observational, single-center cohort study 1069 consecutive patients taking clopidogrel undergoing elective implantation between December 2005 2007. On-treatment was measured in parallel by light transmittance aggregometry, Verify...
Catheter ablation (CA) and minimally invasive surgical (SA) have become accepted therapy for antiarrhythmic drug-refractory atrial fibrillation. This study describes the first randomized clinical trial comparing their efficacy safety during a 12-month follow-up.One hundred twenty-four patients with fibrillation left dilatation hypertension (42 patients, 33%) or failed prior CA (82 67%) were to (63 patients) SA (61 patients). consisted of linear antral pulmonary vein isolation optional...
Early diagnosis of nonacute heart failure is crucial because prompt initiation evidence-based treatment can prevent or slow down further progression. To diagnose new-onset in primary care challenging.This a cross-sectional diagnostic accuracy study with external validation. Seven hundred twenty-one consecutive patients suspected underwent standardized work-up including chest x-ray, spirometry, ECG, N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurement, and echocardiography...
Aims After the introduction of European Society Cardiology (ESC) guidelines on prevention, diagnosis, and treatment infective endocarditis (IE) in 2009, prophylaxis for patients at risk became less strict. We hypothesize that there will be a rise IE after guideline update. Methods Results performed nationwide retrospective trend study using segmented regression analysis interrupted time series. The patient data were obtained via national healthcare insurance database, which collects all...
Serial ultrasonography is reliable for the diagnosis of deep venous thrombosis in symptomatic patients, but low prevalence this group renders approach costly and inconvenient to patients. We studied clinical validity combination a pretest probability score D-dimer test initial evaluation patients suspected thrombosis.Patients with normal concentration (<500 fibrin equivalent units [FEU] microg/L) non-high (<3) had no further testing. Patients high (> or =3) underwent one ultrasonogram. was...
Abstract Background The aim of this randomized single-centre trial was to compare the 2-year results endovenous laser ablation (EVLA) and cryostripping for varicose veins. Methods A total 120 patients with uncomplicated great saphenous veins were equally one two treatments. Principal outcomes measures were: freedom from recurrent on duplex imaging, improvement in Venous Clinical Severity Score (VCSS) Aberdeen Varicose Vein (AVVSS) 6, 12 24 months after treatment. Results Life-table analysis...
Objectives To investigate the impact of genotypes on basis loss-of-function variant CYP2C19*2 and gain-of-function CYP2C19*17 on-treatment platelet reactivity occurrence Thrombolysis in Myocardial Infarction (TIMI) major bleedings 820 clopidogrel-treated patients who underwent elective coronary stenting. Methods On-treatment was quantified using ADP-induced light transmittance aggregometry (LTA) VerifyNow P2Y12 assay. Postdischarge TIMI within 1 year after enrollment were recorded. Results...
Abstract The purpose of this study is to evaluate the efficacy a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) adolescents with irritable bowel syndrome (IBS) functional abdominal pain-not otherwise specified (FAP-NOS) non-guided setting, resembling clinical practice. This prospective multicenter cohort conducted 13 centers included patients aged 12–18 years diagnosed IBS or FAP-NOS. Patients received educational material on FODMAPs,...
Pediatric irritable bowel syndrome (IBS) and functional abdominal pain - not otherwise specified (FAP-NOS) lack effective pharmacologic interventions. We evaluated the efficacy of mebeverine, an antispasmodic agent, effect labeling within a pediatric cohort. This randomized trial was conducted across 13 hospitals. Participants (12-17 years) with IBS or FAP-NOS received mebeverine (200 mg twice daily) placebo for 8 weeks. Treatment labelled as "mebeverine placebo" (blinded label) "mebeverine"...
Objective: Atrial fibrillation (AF) persisting after mitral valve surgery reduces survival due to heart failure and thrombo-embolisms, impairs quality of life. Arrhythmia for AF shows today very satisfying results therefore with appears appealing. This study explores whether combined in view today's is indicated. Methods results: An outcome analysis the arrhythmia patients undergoing exclusive or without tricuspid repair was done. Preoperative baseline characteristics including pattern,...
If drug refractoriness to paroxysmal atrial fibrillation (PAF) occurs, arrhythmia surgery that involves channelling and the exclusion of specific areas can abolish fibrillation. The purpose this study was establish effectiveness safety maze III PAF.Surgery performed in 41 selected patients who had long-standing, symptomatic, drug-refractory, lone PAF. At discharge, 35 (85%) were free, 6 (15%) showed PAF tachycardia. Death or stroke did not occur during a mean follow-up 31+/-16 months. end...
Abstract Background In addition to radiological evaluation, biomarkers may be useful in providing early information on the response treatment, and supporting clinical decision‐making. The objective of this study was investigate carcinoembryonic antigen (CEA) lactate dehydrogenase (LDH) as for assessment patients with advanced non‐small cell lung cancer (NSCLC) treated platinum‐based chemotherapy. Methods A retrospective follow‐up conducted from 2012 2017 among 593 consecutive NSCLC...
INTRODUCTION: Chronic pancreatitis (CP) has a negative impact on quality of life (QoL). Because CP is chronic condition, multiple assessments QoL are required to obtain thorough understanding its patients. Such studies currently lacking. This study aims gain insight into the course and predictors in patients with using prospective longitudinal data from large cohort METHODS: Post hoc analysis consecutive definite registered database between 2011 2019 Netherlands. Patient disease...
<b><i>Objectives:</i></b> The PLATO trial revealed superiority of ticagrelor over clopidogrel for the prevention atherothrombotic events in patients with acute coronary syndrome. However, adverse such as bleeding, dyspnea, and bradycardia were frequently reported, potentially leading to excess early discontinuation (ETD), later confirmed PEGASUS trial. We here evaluated incidence causes ETD a real-world patient cohort high-volume nonacademic percutaneous intervention...