Martin J. Swaans
A5058448512- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Aortic Disease and Treatment Approaches
- Antiplatelet Therapy and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Venous Thromboembolism Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Cardiac tumors and thrombi
- Acute Myocardial Infarction Research
- Cardiac electrophysiology and arrhythmias
- Cardiovascular and Diving-Related Complications
- Vascular Procedures and Complications
- Sarcoidosis and Beryllium Toxicity Research
- Congenital Heart Disease Studies
- Advanced MRI Techniques and Applications
- Orthopaedic implants and arthroplasty
- Vascular Anomalies and Treatments
- Aortic aneurysm repair treatments
St. Antonius Ziekenhuis
2016-2025
Manchester University NHS Foundation Trust
2024
Boston Scientific (Belgium)
2024
Radboud University Medical Center
2024
Leiden University Medical Center
2024
Radboud University Nijmegen
2024
University Medical Center Utrecht
2024
Erasmus MC
2024
Isala
2024
Maastricht University
2024
The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has been well studied.In a randomized, controlled trial, we assigned subgroup were undergoing TAVI did anticoagulation, 1:1 ratio, to receive aspirin alone or plus clopidogrel 3 months. two primary outcomes all (including minor, major, life-threatening disabling...
The roles of anticoagulation alone or with an antiplatelet agent after transcatheter aortic-valve implantation (TAVI) have not been well studied.We performed a randomized trial clopidogrel in patients undergoing TAVI who were receiving oral for appropriate indications. Patients assigned before 1:1 ratio to receive 3 months. two primary outcomes all bleeding and non-procedure-related over period 12 Procedure-related was defined as Bleeding Academic Research Consortium type 4 severe bleeding,...
Mitral regurgitation (MR) is the most prevalent valvular heart disease and, when left untreated, results in reduced quality of life, failure, and increased mortality. valve transcatheter edge-to-edge repair (M-TEER) has matured considerably as a non-surgical treatment option since its commercial introduction Europe 2008. As result major device interventional improvements, well accumulation experience by cardiologists, M-TEER emerged an important therapeutic strategy for patients with severe...
Although women with severe symptomatic aortic stenosis have more complications than men when undergoing surgical valve replacement, they are under-represented in clinical trials. The Randomized researcH womEn all comers wIth Aortic (RHEIA) trial investigates the balance of benefits and risks transcatheter implantation (TAVI) vs. surgery women. Women were randomized 1:1 to transfemoral TAVI a balloon-expandable or surgery. primary composite endpoint was death, stroke, (valve, procedure heart...
Aims After the introduction of European Society Cardiology (ESC) guidelines on prevention, diagnosis, and treatment infective endocarditis (IE) in 2009, prophylaxis for patients at risk became less strict. We hypothesize that there will be a rise IE after guideline update. Methods Results performed nationwide retrospective trend study using segmented regression analysis interrupted time series. The patient data were obtained via national healthcare insurance database, which collects all...
BackgroundOne third of patients undergoing transcatheter aortic-valve implantation (TAVI) have an indication for oral anticoagulation owing to concomitant diseases. Interruption during TAVI may decrease the risk bleeding, whereas continuation thromboembolism.MethodsWe conducted international, open-label, randomized, noninferiority trial involving who were receiving anticoagulants and planning undergo TAVI. Patients randomly assigned in a 1:1 ratio periprocedural or interruption...
Drug-refractory atrial fibrillation (AF) increasingly is being treated with catheter ablation. However, the long-term success rate, expressed as freedom from AF, <50%. Therefore, vitamin K antagonists, all their complications, remain necessary. Recently, left appendage (LAA) occlusion devices were introduced an alternative to antagonists. Here, we investigated whether AF ablation and LAA could be a feasible safe combination in patients symptomatic drug-refractory CHADS(2) score ≥1 or...
Long-term freedom from atrial fibrillation (AF) after catheter ablation (CA) and consequently the potential for stroke reduction remain unpredictable. Percutaneous left appendage closure (LAAC) is an effective mechanical alternative to oral anticoagulation (OAC) prevention in AF patients. This study aims evaluate long-term clinical results of combined CA LAAC one single procedure. Patients with non-valvular who underwent procedure were included retrospective compilation independent...
BACKGROUND: Approximately 15% of saphenous vein grafts (SVGs) occlude during the first year after coronary artery bypass graft surgery (CABG) despite aspirin use. The POPular CABG trial (The Effect Ticagrelor on Saphenous Vein Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting Surgery) investigated whether ticagrelor added to standard improves SVG patency at 1 CABG. METHODS: In this investigator-initiated, randomized, double-blind, placebo-controlled, multicenter trial,...
Abstract Transcatheter therapies for the treatment of structural heart diseases (SHD) have expanded dramatically over last years, thanks to developments and improvements devices imaging techniques, along with increasing expertise operators. Imaging, in particular echocardiography, is pivotal during patient selection, procedural monitoring, follow-up. The assessment patients undergoing transcatheter interventions places demands on imagers that differ from those routine evaluation SHD, there a...
The addition of CT-derived fractional flow reserve (FFR-CT) increases the diagnostic accuracy coronary CT angiography (CCTA). We assessed impact FFR-CT in routine clinical practice on decision-making and patient prognosis patients suspected stable artery disease (CAD).This retrospective, single-center study compared a cohort that received CCTA with to historical before was available. management decisions after rate major adverse cardiac events (MACEs) during 1-year follow-up using chi-square...
Mitral transcatheter edge-to-edge repair (M-TEER) is a guideline-recommended treatment option for patients with severe symptomatic mitral regurgitation (MR). Outcomes the PASCAL system in post-market setting have not been established. The authors report 30-day and 1-year outcomes from MiCLASP (Transcatheter Repair of Regurgitation Edwards Transcatheter Valve System) European clinical follow-up study. Patients symptomatic, clinically significant MR were prospectively enrolled. primary safety...
To determine the prevalence of mitral regurgitation (MR) in a large cohort consecutive patients undergoing clinically indicated echocardiography and to examine distribution primary secondary MR.All an echocardiographic study 19 European centres within 3-month period were prospectively included. MR assessment was performed as recommended by Association Cardiovascular Imaging (EACVI). classified according mechanism or aetiologies reported. A total 63 463 studies reviewed. Any degree described...
Abstract Percutaneous therapeutic options for an increasing variety of structural heart diseases (SHD) have grown dramatically. Within this context continuous expansion devices and procedures, there has been increased demand physicians with specific knowledge, skills, advanced training in multimodality cardiac imaging. As a consequence, new subspecialty ‘Interventional Imaging’ SHD interventions dedicated professional figure, the Imager’ competencies emerged. The interventional imager is...
Preprocedural computed tomography planning improves procedural safety and efficacy of transcatheter aortic valve implantation (TAVI). However, contemporary imaging modalities do not account for device-host interactions.This study evaluates the value preprocedural computer simulation with FEops HEARTguideTM on overall device success in patients challenging anatomies undergoing TAVI a self-expanding supra-annular heart valve.This prospective multicenter observational included anatomy defined...
Importance Patients with atrial fibrillation (AF) who have ischemic stroke despite taking oral anticoagulation therapy (OAT) a very high risk of recurrence. Left appendage occlusion (LAAO) is mechanical prevention strategy that may provide additional protection in patients thromboembolic events under OAT. Objective To compare percutaneous LAAO continuing OAT alone regarding AF had event Design, Setting, and Participants This cohort study was propensity score–matched comparison the STR-OAC...