A5107655566- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Structural Anomalies and Repair
- Healthcare Systems and Practices
- Cardiac Arrest and Resuscitation
- Cardiovascular and Diving-Related Complications
- Takotsubo Cardiomyopathy and Associated Phenomena
- IL-33, ST2, and ILC Pathways
- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- GDF15 and Related Biomarkers
- Coronary Artery Anomalies
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
Université de Montpellier
2015-2025
Centre Hospitalier Universitaire de Montpellier
2015-2024
Hôpital Arnaud de Villeneuve
2014-2024
Inserm
2018-2024
Hôpital Lariboisière
2024
Hôpital Européen Georges-Pompidou
2024
Université Paris Cité
2024
Assistance Publique – Hôpitaux de Paris
2024
Centre National de la Recherche Scientifique
2018-2024
Physiologie et Médecine Expérimentale du Coeur et des Muscles
2019
In patients who have chronic heart failure with reduced left ventricular ejection fraction, severe secondary mitral-valve regurgitation is associated a poor prognosis. Whether percutaneous repair improves clinical outcomes in this patient population unknown.We randomly assigned had mitral (defined as an effective regurgitant orifice area of >20 mm2 or volume >30 ml per beat), fraction between 15 and 40%, symptomatic failure, 1:1 ratio, to undergo addition receiving medical therapy...
Abstract Aims The respective roles of oral anticoagulation or antiplatelet therapy following transcatheter aortic valve implantation (TAVI) remain debated. ATLANTIS is an international, randomized, open-label, superiority trial comparing apixaban to the standard care. Methods and results After successful TAVI, 1500 patients were randomized (1:1) receive 5 mg (2.5 if impaired renal function concomitant therapy) (n = 749) twice daily, care 751). Randomization was stratified by need for chronic...
The appropriate duration of treatment with beta-blocker drugs after a myocardial infarction is unknown. Data are needed on the safety and efficacy interruption long-term to reduce side effects improve quality life in patients history uncomplicated infarction.
Background: No randomized study powered to compare balloon expandable (BE) with self expanding (SE) transcatheter heart valves (THVs) on individual end points after aortic valve replacement has been conducted date. Methods: From January 2013 December 2015, the FRANCE-TAVI nationwide registry (Registry of Aortic Valve Bioprostheses Established by Catheter) included 12 141 patients undergoing BE-THV (Edwards, n=8038) or SE-THV (Medtronic, n=4103) for treatment native stenosis. Long term...
Abstract Background and Aims There is significant potential to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI). The purpose of this study was evaluate effect implementing BENCHMARK best practices on efficiency safety TAVI in 28 sites 7 European countries. Methods This a with severe symptomatic stenosis (AS) balloon-expandable valves before after implementation practices. Principal objectives were reduce hospital length stay (LoS)...
Cardiac biomarkers including troponins are the cornerstone of biological definition acute myocardial infarction. New high-sensitivity cardiac assays determining troponin T (hs-cTnT) as well I ((hs-cTnI) from Abbott and s-cTnI Siemens) raise concerns because their unclear kinetics following peak. This study aims to compare creatine kinases, hs-cTnT, hs-cTnI in patients with ST-segment elevation infarction (STEMI) treated by percutaneous coronary intervention. We prospectively studied 106...
Journal Article Colchicine to prevent sympathetic denervation after acute myocardial infarction: the COLD-MI trial Get access Fabien Huet, Huet Department of Cardiology, Vannes Regional Hospital, 20 Bd Général Maurice Guillaudot, 56000 Vannes, FranceDepartment Montpellier University 191 Av. du Doyen Gaston Giraud, 34295 Cedex 5, FrancePhyMedExp, Université de Montpellier, INSERM, CNRS, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Denis...
Incidence and prognostic of unstable angina after high-sensitivity troponin assesment is controversial. This study evaluated a contemporary population patients with UA defined using high sensitive T (T hs-cTn) measurements significant coronary artery disease (CAD). Consecutive admitted in 2 French university centres as clinical ischemic symptoms hs-cTn dosages undetectable (< 5 ng/L), non-elevated (> 14 ng/L) or mildly elevated (14-50 were included. The primary end-point included major...
This article describes a new technique of LV lead insertion, using transseptal catheterization performed through the right internal jugular vein, to obtain totally endocardial biventricular chronic pacing in end-stage heart failure. Three patients with QRS widening (> 180 ms) linked complete left bundle branch block (n = 2) or ventricular 1) were included this preliminary study. Catheterization was under fluoroscopy and transesophageal echocardiography guidance. Transseptal achieved by...
We describe in this report the development of chronic left main coronary artery (LMCA) occlusion a young patient 2 years after an uncomplicated, successful ablation idiophic ventricular tachycardia. This complication appears to be late consequence trauma LMCA during procedure rather than acute or subacute embolic event.
Abstract Cardiac biomarkers are the cornerstone of biological definition acute myocardial infarction (AMI). The key role troponins in diagnosis AMI is well established. Moreover, kinetics troponin I (cTnI) and creatine kinase (CK) after correlated to prognosis. New technical assessment like high-sensitivity cardiac T (hs-cTnT) raises concerns because its unclear kinetic following peak. This study aims compare cTnI hs-cTnT CK patients with large successfully treated by percutaneous coronary...
Objective To evaluate the changes in transvalvular gradients and incidence of valve haemodynamic deterioration (VHD) following transcatheter aortic replacement (TAVR), according to use anticoagulation therapy. Methods results This multicentre study included 2466 patients (46% men; mean age 81±7 years) who underwent TAVR with echocardiography performed at 12-month follow-up. Anticoagulation therapy was used 707 (28.7%) (AC group). A total 663 received vitamin K antagonists, 44 direct oral...
Natriuretic peptides (BNP and NT-proBNP) are recognized as gold-standard predictive markers in Heart Failure (HF). However, currently ST2 (member of the interleukin 1 receptor family) has emerged marker inflammation, fibrosis cardiac stress. We evaluated CRP prognostic 178 patients with chronic heart failure comparison other classical such clinical established parameters but also biological markers: NT-proBNP, hs-cTnT alone or combination. In multivariate analysis, subsequent addition led to...
Coronary artery disease (CAD) is common in patients undergoing transcatheter aortic valve replacement (TAVR). However, the impact of CAD distribution before TAVR on short- and long-term prognosis remains unclear.We hypothesized that clinical differs according to using FRench Aortic National CoreValve Edwards (FRANCE-2) registry.FRANCE-2 a national French registry including all consecutive performed between 2010 2012 34 centers. Three-year mortality was assessed relation status. defined as at...