Nicolas Michel

ORCID: 0000-0003-1610-8377
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About
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Research Areas
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Function and Risk Factors
  • Pelvic and Acetabular Injuries
  • Cardiac Imaging and Diagnostics
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cardiac Structural Anomalies and Repair
  • Pulmonary Hypertension Research and Treatments
  • Adrenal and Paraganglionic Tumors
  • Patient Safety and Medication Errors
  • Spine and Intervertebral Disc Pathology
  • Venous Thromboembolism Diagnosis and Management
  • Congenital Heart Disease Studies
  • Hormonal Regulation and Hypertension
  • Simulation-Based Education in Healthcare
  • Spinal Fractures and Fixation Techniques
  • Williams Syndrome Research
  • Cardiovascular Effects of Exercise
  • Bone fractures and treatments
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Bariatric Surgery and Outcomes
  • Parathyroid Disorders and Treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Allergic Rhinitis and Sensitization
  • Cardiovascular Disease and Adiposity

Assistance Publique Hôpitaux de Marseille
2011-2023

Centre Hospitalier Universitaire de Poitiers
2019-2023

Hôpital de la Timone
2010-2022

Hospices Civils de Lyon
2021-2022

Centre Hospitalier Universitaire de Montpellier
2021

Protéomique, Réponse Inflammatoire et Spectrométrie de Masse
2019-2020

Institut Pprime
2019

École Nationale Supérieure de Mécanique et d'Aérotechnique
2019

Université de Poitiers
2019

Centre National de la Recherche Scientifique
2019

In patients who have chronic heart failure with reduced left ventricular ejection fraction, severe secondary mitral-valve regurgitation is associated a poor prognosis. Whether percutaneous repair improves clinical outcomes in this patient population unknown.We randomly assigned had mitral (defined as an effective regurgitant orifice area of >20 mm2 or volume >30 ml per beat), fraction between 15 and 40%, symptomatic failure, 1:1 ratio, to undergo addition receiving medical therapy...

10.1056/nejmoa1805374 article EN New England Journal of Medicine 2018-08-27

Left ventricular non-compaction (LVNC) is a cardiomyopathy that may be of genetic origin; however, few data are available about the yield mutation, spectrum genes and allelic variations. The aim this study was to better characterize isolated LVNC in prospective cohort 95 unrelated adult patients through molecular investigation 107 involved cardiomyopathies arrhythmias. Fifty-two pathogenic or probably variants were identified 40 (42%) including 31 (32.5%) with single variant 9 complex...

10.1111/cge.13484 article EN Clinical Genetics 2018-11-24

To assess the additional value of adrenal venous sampling (AVS) to diagnose primary aldosteronism sub-types in patients who have a unilateral nodule detected by computed tomography (CT scan) and should undergo an adrenalectomy.A retrospective study consecutive with undergoing CT scan AVS. Criterion for selective cannulation was equal or higher cortisol level vein compared inferior vena cava. An adrenal-vein aldosterone-to-cortisol ratio at least two times than other side defined...

10.1097/hjh.0b013e32834666af article EN Journal of Hypertension 2011-04-08

Restrictive valvular disease (RVD) has recently been reported in patients after benfluorex exposure. However, little is known about its prevalence and echocardiographic features. The aim of our study was to assess the frequency exposure with RVD describe their characteristics.In a single centre study, final diagnosis unexplained were studied. Patients interrogated for previous use or other appetite-suppressant drugs (ASDs). Forty seven consecutive patients, aged 59 ± 9.6 years, found [42...

10.1093/ejechocard/jer116 article EN European Heart Journal - Cardiovascular Imaging 2011-08-02

Whether left ventricular non-compaction (LVNC) bears a different prognosis than dilated cardiomyopathy (DCM) is still matter of debate.From multicenter French prospective registry, we compared the outcomes 98 patients with LVNC and 65 DCM. The primary endpoint combined cardiovascular death, heart transplantation, hospitalization for events. two groups presented similar but ejection fractions (LVEF) (43.3% in vs. 35.95% DCM, p = 0.001). For this reason, subgroup analysis was performed...

10.3389/fcvm.2022.856160 article EN cc-by Frontiers in Cardiovascular Medicine 2022-05-02

Adamantinoma is a bone tumor which commonly showed in mandible. Its occurrence long bones constitutes rare affection and difficult histological diagnosis This malignant of mesenchymal epithelial origin was discovered the tibia male patient.The authors report case adamantinoma 36- years old. He presented with slowly progressing leg swelling that evolved over 2 without significant clinical manifestation. Complementary examination investigation did not help differential confirmation only...

10.13107/jocr.2250-0685.140 article EN cc-by-nc Journal of Orthopaedic Case Reports 2014-01-06

Abstract Funding Acknowledgements Type of funding sources: None. Background Despite the increasing number studies concerning Left Atrial Strain (LAS), few data are available comparing LAS patients with cardiac amyloidosis (CA) and sarcomeric hypertrophic cardiomyopathies (HCM). Purposes We aimed to perform a comparative multimodal imaging analysis prospective cohort CA HCM. Methods For each enrolled patient, we performed same-day two three-dimension echocardiography (TTE) magnetic resonance...

10.1093/ehjci/jeab289.045 article EN European Heart Journal - Cardiovascular Imaging 2022-02-01

p<0.001).Women underwent less defibrillator implantation (10.9% vs. 15.6%,p=0.032), more alcohol septal ablation (3.5% 1.3% p=0.018) but had similar frequency of myectomy (6.0% 6.0%,p=0.987).Kaplan-Meier analysis showed higher overall (8.4% 5.0%, p=0.026) and cardiovascular (5.5% 2.2%, p=0.004) mortality in women compared with men (picture 1).In multivariable modeling, female gender remained independently associated ], P=0.021) CV .99],P=0.015) after adjustment for all previous statistically...

10.1093/eurheartj/ehy565.p2591 article EN European Heart Journal 2018-08-01

Morbidity and Mortality conference provides the necessary improvement measures for patient safety. However, they are an underused resource mainly because conclusions to be drawn from discussion their implications practice not always well integrated by inpatient care teams. We therefore propose in this study two interventions optimise effectiveness: a passive feedback with wide dissemination e-mail and/or on paper of results teams active situ inter-professional simulation-training programme...

10.1186/s13063-022-06040-2 article EN cc-by Trials 2022-02-02
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