A5077287134- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Pulmonary Hypertension Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Issues in Pregnancy
- Cardiac tumors and thrombi
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Disease and Adiposity
- Cardiac Arrest and Resuscitation
- ECG Monitoring and Analysis
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
Centre Hospitalier de Cannes
2020-2025
Mayo Clinic
2019-2025
WinnMed
2020-2024
Mayo Clinic in Arizona
2020-2024
Mayo Clinic in Florida
2021-2023
Scientific Centre of Monaco
2018-2021
Hôpital de la Timone
2018-2020
Hôpital Pasteur
2018
Centre Hospitalier Universitaire de Nice
2018
Université Côte d'Azur
2018
Risk stratification scheme. aiming at assessing the risk of VAs and SCD in patients with MVP, involving two phases based on clinical imaging context uncovered arrhythmia. In absence ventricular tachycardia, phenotypic features will trigger intensity screening for Green boxes indicate green heart consensus statements yellow statements. High - sustained VT, polymorphic NSVT, fast (>180 bpm) VT/NSVT resulting syncope. ICD = implantable cardioverter defibrillator; LA left atrium; LGE late...
To assess functional tricuspid regurgitation (FTR) determinants, consequences, and independent impact on outcome in degenerative mitral (DMR).All patients diagnosed with isolated DMR 2003-2011, structurally normal leaflets, prospective FTR grading systolic pulmonary artery pressure (sPAP) estimation by Doppler echocardiography at diagnosis were identified long-term analysed. The 5083 eligible [63 ± 16 years, 47% female, ejection fraction (EF) 63 7%, sPAP 35 13 mmHg] presented graded trivial...
Severe aortic stenosis (AS) is the guideline-based indication for valve replacement (AVR), which has markedly increased with transcatheter approaches, suggesting possible increasing AS incidence. However, reported secular trends of incidence remain contradictory and lack quantitative Doppler echocardiographic ascertainment.
Presentation, outcome, and management of females with degenerative mitral regurgitation (DMR) are undefined. We analysed sex-specific baseline clinical echocardiographic characteristics at referral for DMR due to flail leaflets subsequent outcomes.
Abstract Aims Indications for surgery in patients with degenerative mitral regurgitation (DMR) are increasingly liberal all clinical guidelines but the role of secondary outcome determinants (left atrial volume index ≥60 mL/m2, fibrillation, pulmonary artery systolic pressure ≥50 mmHg and moderate to severe tricuspid regurgitation) their impact on post-operative remain disputed. Whether these markers just reflective DMR severity or intrinsically affect survival after is uncertain may have...
Randomized clinical trials demonstrated transcatheter edge-to-edge repair (TEER) efficacy in improving outcome vs. medical management for functional mitral regurgitation, but limited randomized data are available the treatment of degenerative regurgitation (DMR). We aimed to compare older patients treated with TEER unoperated DMR.Registries including consecutive ≥65 years symptomatic severe DMR (MitraSwiss and Minneapolis Heart Institute registries) or (MIDA registry) were analysed. Survival...
Abstract Aims Functional tricuspid regurgitation (FTR) associated with degenerative mitral (DMR) accentuates the severity of heart failure and is a marker poor prognosis. Little known about FTR asymptomatic DMR. Methods results The study included 1249 patients moderate or severe DMR from Mitral Regurgitation International Database‐Quantitative (MIDA‐Q) registry (mean age 64 ± 15 years, 25% female). Despite status, absent/trivial was noted in only 42%, mild 34.5%, 11%, 12.5%. Patients higher...
Left atrial assessment is complex, particularly in heart failure with reduced ejection fraction due to interactions functional mitral regurgitation (FMR). Pilot data suggest that left volumetric/mechanical coupling index (LACI) may be useful, but large outcome are lacking.We enrolled a comprehensively characterized cohort of patients sinus rhythm diagnosis at Mayo Clinic from 2007 2011. Routinely measured volume and tissue-doppler-imaging a' allowed LACI calculation as (left...
Clinical outcome and interventional thresholds for degenerative mitral regurgitation (DMR) were developed in studies of patients at European American institutions (EAIs), but little is known about Asian (AsIs).
Background The prevalence and impact of right ventricular dysfunction (RVD) in degenerative mitral regurgitation (DMR) is unknown. We aimed to determine whether RVD assessed by echocardiography routine clinical practice independently associated with mortality patients DMR. Methods Results used data from the MIDA‐Q (Mitral Regurgitation International DAtabase‐Quantitative) registry, which included isolated DMR due valve prolapse January 2003 2020 5 tertiary centers across North America,...
Mitral valve prolapse (MVP) is responsible for a considerable disease burden but widely heterogeneous. The lack of comprehensive prognostic instrument covering the entire MVP spectrum, encompassing quantified consequent degenerative mitral regurgitation (DMR), hinders clinical management and therapeutic trials.The new Regurgitation International Database Quantitative (MIDA-Q) registry enrolled 8187 consecutive patients (ages 63±16 years, 47% women, follow-up 5.5±3.3 years) first diagnosed...
Background Emerging data suggest important prognostic value to left atrial (LA) characteristics, but the independent impact of LA function on outcome remains unsubstantiated. Thus, we aimed define incremental coupling index (LACI), volumetric and mechanical characteristics calculated as ratio volume tissue Doppler imaging a′, in a large cohort patients with isolated floppy mitral valve. Methods Results All consecutive 4792 (61±16 years, 48% women) valve sinus rhythm diagnosed at Mayo Clinic...
Despite coherent guidelines, management of functional tricuspid regurgitation (FTR) consequences on outcome in the context degenerative mitral (DMR) remains controversial due to lacking series large magnitude with rigorous application guidelines and strict long-term echocardiographic follow-up. Thus, we aimed at gathering such a cohort examine outcomes patients undergoing DMR surgery following guidelines.All consecutive isolated 2005-2015 operated baseline FTR assessment annulus diameter...