A5078443392- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Cardiac Valve Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Cardiovascular Function and Risk Factors
- Gallbladder and Bile Duct Disorders
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Infective Endocarditis Diagnosis and Management
- Renal cell carcinoma treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Gastrointestinal disorders and treatments
- Cardiac Imaging and Diagnostics
- Diverticular Disease and Complications
- Inflammatory Bowel Disease
- Colorectal Cancer Surgical Treatments
- Pancreatitis Pathology and Treatment
- Colorectal Cancer Screening and Detection
- Diabetes Management and Research
- Tissue Engineering and Regenerative Medicine
- Nutrition and Health in Aging
Mayo Clinic
2016-2025
Mayo Clinic in Florida
2015-2024
Kathmandu Medical College Teaching Hospital
2010-2024
WinnMed
2014-2024
Mayo Clinic in Arizona
2013-2024
Evidence (Italy)
2023
Michigan Department of Education
2023
American Urological Association
2023
Cambridge University Hospitals NHS Foundation Trust
2023
Grande International Hospital
2012-2022
Abstract Previous controlled trials are inconclusive regarding the efficacy of ursodeoxycholic acid (UDCA) for treating primary sclerosing cholangitis (PSC). One hundred fifty adult patients with PSC were enrolled in a long-term, randomized, double-blind trial high-dose UDCA (28-30 mg/kg/day) versus placebo. Liver biopsy and cholangiography performed before randomization after 5 years. The outcome measures development cirrhosis, varices, cholangiocarcinoma, liver transplantation, or death....
Background: Functional tricuspid regurgitation (FTR) is common in heart failure with reduced ejection fraction and mostly consequent to pulmonary hypertension. However, the intrinsic clinical implications of FTR are not fully understood. Methods: The cohort all Mayo Clinic patients from 2003 2011 diagnosed stage B-C fraction<50%, grading systolic artery pressure estimation by Doppler echocardiography was identified outcomes were analyzed. Patients pacemakers/defibrillators, organic valve...
BACKGROUND The authors evaluated sarcopenia as a predictor of cancer‐specific survival (CSS) and overall (OS) among patients with urothelial cancer the bladder undergoing radical cystectomy (RC). METHODS lumbar skeletal muscle index (SMI) 205 treated RC for between 2000 2007 was measured. Sarcopenia classified according to international consensus definitions (SMI < 55 cm 2 /m men 39 women). CSS OS were estimated using Kaplan‐Meier method compared log‐rank test. Variables associated...
To define the hitherto unknown aetiology/mechanism distributions of mitral regurgitation (MR) in community and linked clinical characteristics/outcomes.We identified all isolated, moderate/severe MR diagnosed our (Olmsted County, MN, USA) between 2000 2010 classified aetiology/mechanisms. Eligible patients (n = 727) were 73 ± 18 years, 51% females, with ejection fraction (EF) 49 17%. was functional (FMR) 65%, organic (OMR) 32% 2% mixed. Functional to left ventricular remodelling (FMR-v) 38%...
Background. We evaluated the capacity of biomechanical and clinical measures balance to predict future risk recurrent falls in a cohort frail, elderly ambulatory residents 12 Tennessee community nursing homes. Methods. Baseline measurements other potential fall factors were obtained 303 home residents. Balance included biomechanics force platform postural sway (area ellipse mean velocity) measures, which functional reach, Tinetti subscale (adapted from Tinetti's Performance Oriented Mobility...
Abstract BACKGROUND: The objective of this case‐control study was to identify any association metformin intake with the survival patients ovarian cancer. METHODS: In retrospective study, women cancer who received (cases) were compared did not receive (controls). A 2‐layered analysis conducted. preliminary analysis, all cases (the OC cohort) controls at a 1:2 ratio. Subsequently, in definitive only had epithelial EOC 1:3 cohort, matched for age (±5 years), International Federation Gynecology...
We investigated the clinicopathological outcomes of patients treated with cystectomy for pure urothelial carcinoma vs carcinoma, and squamous and/or glandular differentiation.We reviewed records 1,013 who underwent radical cystectomy, including 827 (72%) 186 (18%) differentiation. Of variant histology 132 had differentiation, 41 features 13 each type. Cancer specific survival was estimated using Kaplan-Meier method. The association histological differentiation death from bladder cancer...
No AccessJournal of UrologyAdult Urology1 Mar 2014Long-Term Renal Function Outcomes after Radical Cystectomy Manuel S. Eisenberg, R. Houston Thompson, Igor Frank, Simon P. Kim, Katherine J. Cotter, Matthew K. Tollefson, Dharam Kaushik, Prabin Thapa, Robert Tarrell, and Stephen A. Boorjian EisenbergManuel Eisenberg Department Urology, Mayo Clinic, Rochester, Minnesota , ThompsonR. Thompson FrankIgor Frank KimSimon Kim Yale University, New Haven, Connecticut CotterKatherine Cotter University...
Radical cystectomy continues to be associated with a nonnegligible risk of perioperative death and all cause mortality in the years after surgery remains relatively high. We investigated comparative ability various comorbidity indices predict 5-year radical cystectomy.We evaluated 891 patients who underwent between 1994 2005. The associations American Society Anesthesiologists (ASA) score, Charlson index, Elixhauser index ECOG (Eastern Cooperative Oncology Group) performance status outcomes...
To assess functional tricuspid regurgitation (FTR) determinants, consequences, and independent impact on outcome in degenerative mitral (DMR).All patients diagnosed with isolated DMR 2003-2011, structurally normal leaflets, prospective FTR grading systolic pulmonary artery pressure (sPAP) estimation by Doppler echocardiography at diagnosis were identified long-term analysed. The 5083 eligible [63 ± 16 years, 47% female, ejection fraction (EF) 63 7%, sPAP 35 13 mmHg] presented graded trivial...
Severe aortic stenosis (AS) is the guideline-based indication for valve replacement (AVR), which has markedly increased with transcatheter approaches, suggesting possible increasing AS incidence. However, reported secular trends of incidence remain contradictory and lack quantitative Doppler echocardiographic ascertainment.
To our knowledge long-term oncologic outcomes following partial cystectomy for urothelial carcinoma remain to be defined. We evaluated patterns of recurrence and survival among matched patients treated with vs radical bladder cancer.We identified 86 who underwent pT1-4N0-1Mx between 1980 2006 at institution. They were 1:2 undergoing based on age, gender, pathological T stage receipt neoadjuvant chemotherapy. Survival was estimated using Kaplan-Meier analysis compared the log rank test.Median...
No AccessJournal of UrologyAdult Urology1 May 2013Outcomes Following Radical Cystectomy for Nested Variant Urothelial Carcinoma: A Matched Cohort Analysis Brian J. Linder, Igor Frank, John C. Cheville, R. Houston Thompson, Prabin Thapa, Robert F. Tarrell, and Stephen A. Boorjian LinderBrian Linder Department Urology, Mayo Clinic, Rochester, Minnesota , FrankIgor Frank ChevilleJohn Cheville Pathology, ThompsonR. Thompson ThapaPrabin Thapa Health Sciences Research, TarrellRobert Tarrell...
Background: Echocardiographic quantitation of degenerative mitral regurgitation (DMR) is recommended whenever possible in clinical guidelines but criticized and its scalability to routine practice doubted. We hypothesized that echocardiographic DMR quantitation, performed by multiple practitioners, predicts independently long-term survival thus essential management. Methods: included patients diagnosed with isolated valve prolapse from 2003 2011 any degree quantified physician/sonographer...