A5001124285- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Sex work and related issues
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Herpesvirus Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Adolescent Sexual and Reproductive Health
- Cervical Cancer and HPV Research
- HIV-related health complications and treatments
- Reproductive tract infections research
- Cardiac Valve Diseases and Treatments
- HIV/AIDS drug development and treatment
- Breastfeeding Practices and Influences
- Genital Health and Disease
- Infective Endocarditis Diagnosis and Management
- Tuberculosis Research and Epidemiology
- Syphilis Diagnosis and Treatment
- Opioid Use Disorder Treatment
- HIV/AIDS Impact and Responses
- Metabolism and Genetic Disorders
- Infant Nutrition and Health
- Global Maternal and Child Health
- Healthcare Systems and Practices
Inserm
2016-2025
Université de Montpellier
2016-2025
Centre Hospitalier Universitaire de Montpellier
2015-2024
Établissement Français du Sang
2016-2024
Pathogenesis and Control of Chronic and Emerging Infections
2020-2024
University Teaching Hospital
2016-2023
Institut Universitaire de Recherche Clinique
2017-2023
Weatherford College
2022
Institut National de Recherche en Santé Publique
2022
Université des Antilles
2022
Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated increased genital shedding of human immunodeficiency 1 (HIV-1) RNA and HIV-1 transmissibility.
The recent Zika virus (ZIKV) epidemic has highlighted the poor knowledge on its physiopathology. Recent studies showed that ZIKV of Asian lineage, responsible for this international outbreak, causes neuropathology in vitro and vivo. However, two African lineages exist is currently found circulating Africa. original strain was also suggested to be neurovirulent but laboratory usage been criticized due multiple passages. In study, we compared French Polynesian (Asian) an isolated Central...
We investigated the performance of dried blood spots (DBS) in hepatitis C virus (HCV) diagnosis using modified commercial tests. Paired DBS and serum samples were collected from 200 patients: 100 patients with anti-HCV antibodies (anti-HCV), including 62 detectable HCV RNA, without anti-HCV. The sample consisted three drops approximately 50 microL whole applied to a paper card, which was then stored at -20 degrees within 48 hours collection. Using Ortho 3.0 enzyme-linked immunosorbent assay...
Human papillomavirus (HPV) infection and cervical squamous intraepithelial lesions (SILs) were studied in 379 high-risk women. DNA was detected 238 of 360 (66.1%) the beta-globin-positive samples, 467 HPV isolates belonging to 35 types identified. Multiple (2–7 types) infections observed 52.9% HPV-infected The most prevalent HPV-52 (14.7%), HPV-35 (9.4%), HPV-58 HPV-51 (8.6%), HPV-16 (7.8%), HPV-31 (7.5%), HPV-53 (6.7%), HPV-18 (6.4%). immunodeficiency virus type 1 (HIV-1) seroprevalence...
Postoperative endophthalmitis (POE) often results in severe visual impairment. In clinical studies, an intracameral cefuroxime injection at the end of surgery was found to be effective reducing incidence POE. Two important issues are retinal safety and its use for patients with perioperative capsular rupture where risk POE is dramatically increased.To assess effectiveness sodium prevention possible cases a lens.Population-based cohort study 40 years age or older who underwent cataract 1 1546...
To estimate population-wide hepatitis B and C seroprevalence using dried blood spot samples acquired for human immunodeficiency virus (HIV) surveillance as part of the 2010-2011 Demographic Health Survey in Burkina Faso.We used database during multistage, clustered, population-based survey, which 15 377 participants completed questionnaires provided HIV testing. We extracted sociodemographic geographic data including age, sex, ethnicity, education, wealth, marital status region each...
<b>Objectives:</b> Bacterial vaginosis (BV) and <i>Herpes simplex</i> virus type-2 (HSV-2) have been linked to an increased risk of HIV-1 acquisition. Recent research suggests association between BV HSV-2 acquisition, but the converse has not studied. Here, we investigate whether exists infection <b>Methods:</b> We examined determinants occurrence in a cohort female sex workers Burkina Faso. Participants were followed every 3 months for diagnosis genital infections report sexual behaviours....
Objective: To demonstrate a causal relationship between herpes simplex virus 2 (HSV-2) and increased genital HIV-1-RNA shedding in women on HAART. Design: A randomized, double-blind, placebo-controlled trial of herpes-suppressive therapy (valacyclovir 500 mg twice day) HIV-1/HSV-2-infected taking HAART Burkina Faso. Methods: Participants were followed for total 12 biweekly visits before after randomization. The presence frequency plasma HIV-1 RNA, HSV-2 assessed using summary measures,...
To describe the effect of antiretroviral therapy (ART) and HIV-related factors on high-risk human papillomavirus (HR-HPV) high-grade cervical intraepithelial neoplasia lesions (CIN2+) among women living with HIV/AIDS (WLHA) in sub-Saharan Africa.Prospective cohort WLHA Ouagadougou, Burkina Faso (BF) Johannesburg, South Africa (SA). Recruitment was stratified by ART status.At baseline endline (median 16 months), samples, biopsies were analyzed for HPV genotyping (InnoLiPA) histology. Logistic...
Background. The new coronavirus SARS-CoV-2, responsible for the Covid-19 pandemic, uses angiotensin converting enzyme type 2 (ACE2), a physiological inhibitor of renin aldosterone system (RAAS), as cellular receptor to infect cells. Since RAAS can induce and modulate pro-inflammatory responses, it could play key role in pathophysiology Covid-19. Thus, we aimed determine levels plasma indicators activation series consecutively admitted patients our clinic. Methods. Plasma were measured, among...
Abstract Background Anemia is a significant problem in patients on ICU. Its commonest cause, iron deficiency (ID), difficult to diagnose the context of inflammation. Hepcidin new marker ID. We aimed assess whether hepcidin levels would accurately guide treatment ID critically ill anemic after prolonged ICU stay and affect post-ICU outcomes. Methods In controlled, single-blinded, multicenter study, (WHO definition) with an ≥ 5 days were randomized when discharge was expected either...
Journal Article Colchicine to prevent sympathetic denervation after acute myocardial infarction: the COLD-MI trial Get access Fabien Huet, Huet Department of Cardiology, Vannes Regional Hospital, 20 Bd Général Maurice Guillaudot, 56000 Vannes, FranceDepartment Montpellier University 191 Av. du Doyen Gaston Giraud, 34295 Cedex 5, FrancePhyMedExp, Université de Montpellier, INSERM, CNRS, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Denis...