A5034476139- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Antiplatelet Therapy and Cardiovascular Diseases
- Infectious Aortic and Vascular Conditions
- Infective Endocarditis Diagnosis and Management
- Heart Failure Treatment and Management
- ECG Monitoring and Analysis
- Nutritional Studies and Diet
- Cardiovascular Effects of Exercise
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Streptococcal Infections and Treatments
- Mesenchymal stem cell research
- Muscle Physiology and Disorders
- Occupational and environmental lung diseases
- Cholesterol and Lipid Metabolism
- Vasculitis and related conditions
- Edible Oils Quality and Analysis
- Autopsy Techniques and Outcomes
Universidad de Navarra
2001-2024
Clinica Universidad de Navarra
2013-2024
Azienda Ospedaliero-Universitaria di Modena
2022
University of Liverpool
2021-2022
Liverpool Heart and Chest Hospital
2021-2022
Aalborg University
2021-2022
Navarre Institute of Health Research
2021-2022
Laboratoire Informatique d'Avignon
2022
University of Modena and Reggio Emilia
2022
Centro de Investigación Biomédica en Red
2021
Aims To investigate the clinical features, echocardiographic characteristics, management, and prognostic factors of mortality aorto-cavitary fistulization (ACF) in infective endocarditis (IE). Extension infection aortic valve IE beyond valvular structures may result peri-annular complications with resulting necrosis rupture, subsequent development ACF. Aorto-cavitary communications create intra-cardiac shunts, which further deterioration haemodynamic instability. Methods results In a...
Radiofrequency ablation creates irreversible cardiac damage through resistive heating and this temperature change results in a generator impedance drop. Evaluation of novel local (LI) technology measured exclusively at the tip catheter found that larger LI drops were indicative more effective lesion formation. We aimed to evaluate whether drop is associated with conduction block patients paroxysmal atrial fibrillation (AF) undergoing pulmonary vein isolation (PVI).Sixty underwent LI-blinded...
Long-term freedom from atrial fibrillation (AF) after catheter ablation (CA) and consequently the potential for stroke reduction remain unpredictable. Percutaneous left appendage closure (LAAC) is an effective mechanical alternative to oral anticoagulation (OAC) prevention in AF patients. This study aims evaluate long-term clinical results of combined CA LAAC one single procedure. Patients with non-valvular who underwent procedure were included retrospective compilation independent...
Left atrial appendage (LAA) is the source of thrombi in up to 90% patients with non-valvular fibrillation (AF). Catheter ablation (CA) an effective treatment for symptomatic AF and, selected cases, LAA occlusion devices have been introduced as alternative oral anticoagulants (OACs). The safety and feasibility combining CA percutaneous closure (LAAC) are unknown. Patients drug-refractory AF, CHADS2 score ≥1, CHA2DS2-VASc ≥2 were included. consisted pulmonary vein isolation or without roof...
Although transplantation of skeletal myoblast (SkM) in models chronic myocardial infarction (MI) induces an improvement cardiac function, the limited engraftment remains a major limitation. We analyse pre-clinical model whether sequential autologous SkM by percutaneous delivery was associated with increased cell and functional benefit.Chronically infarcted Goettingen minipigs (n = 20) were divided four groups that received either media control or one, two, three doses (mean 329.6 x 10(6)...
Maps obtained by means of electroanatomic high-density mapping (HDM) systems have shown their use in the identification conduction gaps experimental atrial linear lesion models. The objective this study was to assess HDM recognition reconnection pulmonary veins (PV) redo fibrillation (AF) ablation procedures. One hundred and eight patients were included a non-randomized that assessed PV compared control group received conventional non-fluoroscopic guidance with circular multipolar catheter...
This analysis was performed to evaluate the transition of local impedance (LI) drop during pulmonary vein isolation (PVI) durable block and mature lesion formation based on 3-month mapping procedures.A radiofrequency catheter measuring LI has been shown be effective for performing PVI in patients with paroxysmal atrial fibrillation. Previous demonstrated predictive segment conduction an fibrillation ablation procedure.Fifty-eight who had undergone LI-blinded de novo returned a procedure....
The 4S-AF scheme [Stroke risk, Symptom severity, Severity of atrial fibrillation (AF) burden, Substrate severity] has recently been described as a novel approach to in-depth characterization AF. We aim determine if the would be useful for AF and provides prognostic information in real-world patients.The Spanish French cohorts EORP-AF Long-Term General Registry were included. baseline was calculated related primary management strategy (rhythm or rate control). Follow-up performed at 1-year...
Abstract Background Contact force catheters (CF) in combination with high-resolution 3D mapping are the gold standard for treatment of complex arrhythmias. Stable CF and catheter position increase both safety effectiveness energy delivery. To date, local impedance (LI) is only established parameter real-time measure lesion quality. Other methods tend to use surrogate parameters. Catheter ablation may be further improved by combining LI. Purpose LOCALIZE assessed utility LI addition...
Perforation of the right ventricle during placement pacing electrodes is a well-documented complication. Most these perforations occur intraoperatively and rarely cause symptoms. This case report describes fatal cardiac perforation that occurred 10 days after implantation permanent pacemaker. complication should be considered as one potential mechanisms responsible for high rate sudden death observed in paced patients first year pacemaker implantation.
Ultrahigh-density-voltage mapping (uHDV M) is a new tool that can add insights into the pathophysiology of atrial fibrillation (AF). The aim this study was to evaluate performance uHDV M in predicting postablation AF recurrence (AFR).We included 98 consecutive patients undergoing pulmonary vein isolation for (40.8% persistent) using an system and followed 1 year. left atrium (LA) mean voltage (Vm ) Vslope (slope histogram calculated by linear interpolation, with relative frequency on...
Background The Prevention With Mediterranean Diet (PREDIMED) trial supported the effectiveness of a nutritional intervention conducted by dietitian to prevent cardiovascular disease. However, effect remote follow diet has been less explored. Objective This study aims assess remotely provided diet–based in obtaining favorable dietary changes context secondary prevention atrial fibrillation (AF). Methods PREvention recurrent arrhythmias with (PREDIMAR) is 2-year multicenter, randomized,...
Atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) is usually associated to conduction gaps in veins (PVs). Our objective was characterize patients with recurrences a first radiofrequency (RF) or cryoballoon (CB) PVI procedure, using high-density mapping (HDM) system. Fifty AF procedure (pre-RF 25 patients; pre-CB patients) were included at two centres. Activation map (AM) and voltage (VM) of the left atrium PVs built HDM Rhythmia® Superior reconnected more frequently...
Current guidelines recommend adequate anticoagulation for at least 3 weeks pre- and 4 post-direct current cardioversion (DCCV) to reduce thrombo-embolic risk in patients with atrial fibrillation (AF) lasting greater than 48 h. No specific recommendations exist DCCV that have undergone left appendage occlusion (LAAO), many of whom are ineligible anticoagulation. This study aims observe the efficacy safety post-LAAO everyday clinical practice.This prospective multicenter registry included...
Abstract Introduction Low‐voltage activity beyond pulmonary veins (PVs) may contribute to the failure of ablation atrial fibrillation (AF) in long term. We aimed assess presence gaps (PVG) and residual potential (residual antral [RAP]) within scar by means an ultra‐high‐density mapping (UHDM) system. Methods studied consecutive patients from CHARISMA registry who were undergoing AF had complete characterization PV activity. The Lumipoint™ (Boston Scientific) map‐analysis tool was used...
Background First description of a technique for left atrium transseptal puncture (TSP) with minimal radiation exposure by using the nonfluoroscopic MediGuide™ tracking system (MG; St. Jude Medical, Paul, MN, USA) without assistance intracardiac echocardiography. Methods This study included 31 consecutive patients atrial fibrillation undergoing an MG‐assisted percutaneous catheter ablation procedure. A Brockenbrough needle (BRK) is connected to standard pressure transducer through two‐input...