A5103200172- Microscopic Colitis
- Celiac Disease Research and Management
- Inflammatory Bowel Disease
- Clinical Nutrition and Gastroenterology
- Cardiac Arrhythmias and Treatments
- Immunodeficiency and Autoimmune Disorders
- Viral Infections and Immunology Research
- Cardiac Imaging and Diagnostics
- Helicobacter pylori-related gastroenterology studies
- Atrial Fibrillation Management and Outcomes
- Cystic Fibrosis Research Advances
- Child Nutrition and Feeding Issues
- Eosinophilic Esophagitis
- Cardiac Structural Anomalies and Repair
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Cardiac pacing and defibrillation studies
- Gastrointestinal disorders and treatments
- Cardiovascular Function and Risk Factors
- Abdominal Surgery and Complications
- Systemic Lupus Erythematosus Research
- Eating Disorders and Behaviors
- Diabetes and associated disorders
- Cancer Genomics and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
Clinica Universidad de Navarra
2012-2025
Universidad de Navarra
2015-2024
Massachusetts General Hospital
2021
Toronto General Hospital
2021
Instituto Maimónides de Investigación Biomédica de Córdoba
2021
Navarre Institute of Health Research
2016
Bambino Gesù Children's Hospital
2001-2011
Istituti di Ricovero e Cura a Carattere Scientifico
2000-2008
Boston Children's Hospital
2008
Ludwig-Maximilians-Universität München
2007
Left atrial appendage (LAA) is the source of thrombi in up to 90% patients with non-valvular fibrillation (AF). Catheter ablation (CA) an effective treatment for symptomatic AF and, selected cases, LAA occlusion devices have been introduced as alternative oral anticoagulants (OACs). The safety and feasibility combining CA percutaneous closure (LAAC) are unknown. Patients drug-refractory AF, CHADS2 score ≥1, CHA2DS2-VASc ≥2 were included. consisted pulmonary vein isolation or without roof...
Recently, genome-wide association analyses have identified single nucleotide polymorphisms in the IRGM gene (rs1000113 and rs4958847) as strong candidate susceptibility factors for Crohn's disease (CD). The aim of our study was to test whether these variants are associated with inflammatory bowel (IBD) adult- childhood-onset Italian patients.Allele genotype frequencies rs1000113 rs4958847 were determined 823 CD (265 younger than 19 years at diagnosis), 353 ulcerative colitis (UC) (130 578...
Abstract Cardiovascular protein therapeutics such as neuregulin (NRG1) and acidic-fibroblast growth factor (FGF1) requires new formulation strategies that allow for sustained bioavailability of the drug in infarcted myocardium. However, there is no FDA-approved injectable delivery platform due to translational concerns about biomaterial administration through cardiac catheters. We therefore sought evaluate efficacy percutaneous intramyocardial injection poly(lactic-co-glycolic acid)...
Background/objectives: Cardiovascular risk (CVR) stratification in clinical settings remains limited. This study aims to evaluate parameters that could improve the identification of higher-than-expected coronary artery disease (CAD) CT scan coronarography. Methods: In a cross-sectional asymptomatic patients from Integrated Assessment Program (ICAP), volunteers aged 40-80 without diagnosed cardiovascular were assessed. CVR factors like obesity, lipid and glucose profiles, liver fibrosis...
ABSTRACT Background: Inflammatory bowel disease (IBD) present in childhood 15% to 25% of cases. The aim therapy children is not only guarantee normal growth but also prevent relapse and maintain remission. Steroids are effective induce remission; however, resistance, dependency, irreversible side effects can develop. this study was determine whether treatment with repeated infusions autologous red blood cells (RBCs) loaded dexamethasone 21‐phosphate (Dex 21‐P) safe allows maintenance...
Some reports highlight the potential application of fecal calprotectin as a direct biomarker intestinal inflammation and, therefore, support in choosing candidates for endoscopy. The value 100 μg/g was recently assumed best cutoff this assay. purpose study to assess diagnostic precision assay, compared histology, stool-screening inflammatory bowel disease (IBD) among group prospectively identified patients referred recurrent abdominal pain and altered habits.Between 1999 2007 we evaluated...
Thyroid autoimmunity (TA) is often associated with coeliac disease (CD).To evaluate, in children and adolescents CD on a gluten-free diet (GFD): (1) the prevalence of TA; (2) impact TA growth need for L-thyroxine (L-T4) treatment, during longitudinal survey.Between January December 2005, 545 patients CD, prospectively followed up until 2007, 622 controls were screened TA. Antithyroperoxidase antithyroglobulin antibodies assayed and, if positive, serum free tri-iodothyronine, thyroxine...
Patients with Down's syndrome (DS) or celiac disease (CD) have altered immune systems. Autoimmune diseases been described in both conditions; the coexistence of DS and CD has occasionally reported, but a clear relationship not definitely established. In this study we determined IgA antigliadin antibodies (IgA-AGA) 155 children DS, results were compared those control groups formed by 320 affected upper-respiratory tract infections 115 gastrointestinal symptoms normal jejunal mucosa. High...
To assess the efficacy and safety of azathioprine in a paediatric population with inflammatory bowel disease.One hundred twenty-three Italian children treated were studied retrospectively. The treatment duration causes its discontinuation, side-effects variation corticosteroid dose assessed.The mean age at disease diagnosis was 9.8 +/- 3.6 years, start therapy 11.8 4.3 years. 19 16 months. Fifty patients (41%) stopped due to surgery (12%), prolonged remission (11%), non-response (7%), severe...
Patients with eating disorders can refer to a variety of gastrointestinal symptoms, sometimes justify reduced food intake and vomiting. The authors investigated whether adolescent patients dyspeptic symptoms have altered gastric electric activity abnormal emptying as assessed respectively by electrogastrography scintigraphy.Twenty-eight (18 anorexia 10 bulimia) 16 healthy volunteers underwent electrogastrography; 20 the 28 (14 6 scintigraphy. Electrogastrography bipolar recording lasted 1...
Short-bowel syndrome (SBS) either in adults or children is considered as an indication to small-bowel transplantation (SBTx), particularly its most severe form with a residual bowel length below 20 cm.