Muhammad A. Rizvi
A5001690601- Cancer Immunotherapy and Biomarkers
- Viral Infections and Immunology Research
- Cardiac Structural Anomalies and Repair
- Urinary and Genital Oncology Studies
- CAR-T cell therapy research
- Cardiac Imaging and Diagnostics
- Atherosclerosis and Cardiovascular Diseases
- Bladder and Urothelial Cancer Treatments
- Pericarditis and Cardiac Tamponade
- Neuroendocrine Tumor Research Advances
- Cell Adhesion Molecules Research
- Radiopharmaceutical Chemistry and Applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Angiogenesis and VEGF in Cancer
- Takotsubo Cardiomyopathy and Associated Phenomena
- Medical Imaging Techniques and Applications
- Heart Failure Treatment and Management
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- HER2/EGFR in Cancer Research
- Peptidase Inhibition and Analysis
- Advanced Breast Cancer Therapies
- Acute Myocardial Infarction Research
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
Lehigh Valley Hospital-Pocono
2019-2024
Lehigh Valley Health Network
2020-2024
Lehigh Valley Hospital
2020
Massachusetts General Hospital
2019
Boston University
2008-2010
Abstract Aims Myocarditis is a potentially fatal complication of immune checkpoint inhibitors (ICI). Sparse data exist on the use cardiovascular magnetic resonance (CMR) in ICI-associated myocarditis. In this study, CMR characteristics and association between features events among patients with myocarditis are presented. Methods results From an international registry myocarditis, clinical, CMR, histopathological findings were collected. Major adverse (MACE) composite death, cardiogenic...
Neoadjuvant chemotherapy (NAC) has proven survival benefits for patients with invasive urothelial carcinoma of the bladder, yet its role upper tract (UTUC) remains undefined. We conducted a multicenter, single-arm, phase II trial NAC gemcitabine and split-dose cisplatin (GC) high-risk UTUC before extirpative surgery to evaluate response, survival, tolerability.
Influenza vaccination (FV) is recommended for patients with cancer. Recent data suggested that the administration of FV was associated an increase in immune-related adverse events (irAEs) among on immune checkpoint inhibitors (ICIs). Myocarditis uncommon but serious complication ICIs and may also result from infection influenza. There are no testing relationship between development myocarditis ICIs.Patients who developed (n = 101) (cases) were compared to ICI-treated 201) without (controls)....
Background Myocarditis is a highly morbid complication of immune checkpoint inhibitor (ICI) use that remains inadequately characterized. The QRS duration and the QTc interval are standardized electrocardiographic measures prolonged in other cardiac conditions; however, there no data on their utility ICI myocarditis. Methods From an international registry, ECG parameters were compared between 140 myocarditis cases 179 controls across multiple time points (pre-ICI, prior to myocarditis, at...
The treatment of metastatic breast cancer has undergone significant changes in recent years. New classes medications have been approved by the Food and Drug Administration (FDA) for use clinical practice to extend progression-free survival overall along with increasing response rate. Here, we present a case report pneumonitis as rare side effect palbociclib hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (ERBB2−) addition endocrine therapy. We also review...
Neuroendocrine tumors (NETs), also known as carcinoid tumors, are a heterogeneous group of neoplasms that arise from cells throughout the neuroendocrine system, most commonly arising gastrointestinal (GI) tract, lungs, and bronchi. Myocardial metastasis is rare with an incidence among metastatic patients 4%. They generally asymptomatic detected incidentally. Infiltrative myocardial secondary to tumor exceedingly only single-digit cases reported in literature. We report case 65-years-old...
You have accessJournal of UrologySunday Next Frontier (LBA)1 Apr 2019LBA-17 MULTICENTER PROSPECTIVE PHASE II CLINICAL TRIAL OF GEMCITABINE AND CISPLATIN AS NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH HIGH-GRADE UPPER TRACT UROTHELIAL CARCINOMA Jonathan A. Coleman*, Nathan C. Wong, Daniel D. Sjoberg, Nicholas Silva, Bernard H. Bochner, Guido Dalbagni, S. Machele Donat, Harry W. Herr, Eugene Cha, Timothy Donahue, Pietzak, Hikmat Al-Ahmadie, Nicole Benfante, Anoop Meraney, Steven Shichman,...
Small bowel malignancies are relatively rare, accounting for only 3% of all gastrointestinal cancers. Duodenum is the most common location among small cancers, followed by Jejunum and then Ileum. Duodenal adenocarcinoma produces vague symptoms, leading to late presentation a poor prognosis compared similarly staged colon cancer. It rare have brain metastasis in duodenal adenocarcinoma, not many case reports been reported. Only approximately 6% patients with malignancy metastasis. Here, we...
Rothmund-Thomson syndrome (RTS) is an exceedingly infrequent genetic disorder characterized by a multitude of skin findings collectively known as poikiloderma. In normal cells, the RECQL4 gene involved in DNA replication and repair. RTS caused mutation gene, which results increased predilection to develop various malignancies. Osteosarcomas cancers are typically associated with this syndrome. We present rare case signet-ring cell gastric adenocarcinoma patient RTS.
Introduction: Myocarditis is as a major immune-related adverse event following the use of immune checkpoint inhibitors (ICI). Global radial strain (GRS) reflects both longitudinal and circumferential fiber shortening but no data exist regarding its utility for diagnosis risk stratification ICI-myocarditis. Hypothesis: We hypothesized that GRS from echocardiography would be reduced in patients with ICI-myocarditis reduction have prognostic implications. Methods: Leveraging multicenter...
Introduction: Myocarditis is a rare but highly morbid complication of immune-checkpoint inhibitors (ICI) use. Improved methods for detection and risk stratification are needed. Cytotoxic chemotherapy associates with reduced global circumferential strain (GCS) no data available on the utility GCS in ICI myocarditis. Hypothesis: We hypothesized that by echocardiography would be myocarditis magnitude reduction have prognostic implications. Methods: In this retrospective cohort, from 75 patients...