A5017065397- Cancer survivorship and care
- Health and Medical Studies
- Childhood Cancer Survivors' Quality of Life
- Medical Practices and Rehabilitation
- Family Support in Illness
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Palliative Care and End-of-Life Issues
- Psychology, Coaching, and Therapy
- Health, psychology, and well-being
- Patient-Provider Communication in Healthcare
- Musculoskeletal pain and rehabilitation
- Health Systems, Economic Evaluations, Quality of Life
- Cancer-related cognitive impairment studies
- Chronic Disease Management Strategies
- Psychiatric care and mental health services
- Clinical practice guidelines implementation
- Asthma and respiratory diseases
- Medical and Health Sciences Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac pacing and defibrillation studies
- Mental Health and Psychiatry
- Delphi Technique in Research
- Psychosomatic Disorders and Their Treatments
University of Würzburg
2015-2024
Comprehensive Cancer Center Mainfranken
2015-2024
Zimmer Biomet (Germany)
2019-2024
Universitätsklinikum Würzburg
2005-2023
Institut für Medizinische Biometrie, Informatik und Epidemiologie
2021
European Neuroendocrine Tumor Society
2017
Universität Hamburg
2000-2014
University Medical Center Hamburg-Eppendorf
2000-2014
Heidelberg University
1988-2014
University Hospital Heidelberg
2014
Purpose To provide the 4-week prevalence estimates of mental disorders in cancer populations. Patients and Methods We enrolled adult patients with from in- outpatient care facilities, using a proportional stratified random sample based on nationwide incidence Germany. who scored 9 or above Patient Health Questionnaire (PHQ-9) were administered to standardized computer-assisted Composite International Diagnostic Interview for adapted (CIDI-O). A those PHQ-9 score that was less than selected...
Psychological distress is common in cancer patients, and awareness of its indicators essential. We aimed to assess the prevalence psychological identify problems indicative high distress.We used thermometer (DT) 34-item problem list measure 3724 patients (mean age 58 years; 57% women) across major tumor entities, enrolled an epidemiological multicenter study. To distress-related problems, we conducted monothetic analyses.We found levels (DT ≥ 5) 52% patients. The most prevalent were fatigue...
<h3>Importance</h3> Depression is frequent in patients with heart failure and associated adverse clinical outcomes. Long-term efficacy safety of selective serotonin reuptake inhibitors these are unknown. <h3>Objective</h3> To determine whether 24 months treatment escitalopram improves mortality, morbidity, mood chronic systolic depression. <h3>Design, Setting, Participants</h3> The Effects Selective Serotonin Re-Uptake Inhibition on Morbidity, Mortality, Mood Depressed Heart Failure Patients...
Background— Trials investigating efficacy of disease management programs (DMP) in heart failure reported contradictory results. Features rendering specific interventions successful are often ill defined. We evaluated the mode action and effects a nurse-coordinated DMP (HeartNetCare-HF, HNC). Methods Results— Patients hospitalized for systolic were randomly assigned to HNC or usual care (UC). Besides telephone-based monitoring education, addressed individual problems raised by patients,...
Article AbstractBackground: Psychiatric side effects of interferon alfa are frequently observed in the therapy patients with chronic hepatitis C infection. The goal present study was to assess prospectively incidence, spectrum, and extent psychiatric symptoms receiving as compared an untreated reference group. Method: 104 were consecutively enrolled a prospective longitudinal study. treatment group (N = 84) received alfa-2b for up 12 months, 20) no treatment. Patients who began between...
Background: This study addresses the question of whether coping and emotional state are predictors survival among patients with lung cancer.The hypotheses were (1) active is linked longer time (2) depressive coping, distress, depression shorter survival. Methods:The was based on a sample 103 who investigated after their diagnosis before beginning primary treatment.The psychological variables assessed by means self-reports interviewer ratings.After follow-up 7 to 8 years, 92 had died; data...
Abstract Objective Anxiety in cancer patients may represent a normal psychological reaction. To detect with pathological levels, appropriate screeners established cut‐offs are needed. Given that previous research is sparse, we investigated the diagnostic accuracy of 2 frequently used screening tools detecting generalized anxiety disorder (GAD). Methods We data multicenter study including 2141 patients. Diagnostic was for Generalized Disorder Screener (GAD‐7) and module Hospital Depression...
<b><i>Background:</i></b> Psychological problems are common in cancer patients. For the purpose of planning psycho-oncological interventions and services tailored to specific needs different patient populations, it is necessary know what extent psychological meet criteria mental disorders. The this study was estimate 12-month lifetime prevalence rates disorders <b><i>Methods:</i></b> A representative sample patients with tumour entities stages...
The aim of this study was to compare the levels anxiety and depression in cancer patients with those general population, examine age gender differences depression, analyse impact several socio-demographic clinical parameters on test measurement invariance Hospital Anxiety Depression Scale (HADS).A sample 3,785 German a 2,747 people population were examined using HADS.Patients more anxious but slightly less depressed than age- gender-matched individuals population. Young particularly affected...
Abstract Objective Although one‐third of cancer patients are perceived to have a need for psychological support based on the percentage mental disorders, little is known about actual utilization care in cancer. We aimed assess patients' reported use and its correlates large, representative sample. Methods In multicenter, cross‐sectional study Germany, 4020 (mean age 58 years, 51% women) were evaluated. obtained self‐reports psychotherapy counseling. measured distress with Distress...
Summary Background : Psychiatric side‐effects may require dose reduction or premature discontinuation of interferon therapy in chronic hepatitis C. New strategies are needed order to prevent the termination therapy. Aim To evaluate prospectively efficacy and tolerability antidepressant (paroxetine, a selective serotonin reuptake inhibitor) patients with C treated interferon‐α who have developed interferon‐induced major depression. Methods A sub‐group 14 individuals from 121 consecutively...
What is meant by intention-to-treat? Why should data be analyzed in controlled trials a way that all participants are included the group to which they were randomly assigned, regardless of whether completed intervention given group? In this Tutorial, logic intention-to-treat principle outlined. It shown study results may biased excluding patients post hoc thus producing spurious effects do not exist population under study. The strategy avoids bias.
Empirical studies investigating the prevalence of mental disorders and psychological distress in cancer patients have gained increasing importance during recent years, particularly with objective to develop implement psychosocial interventions within care system. Primary purpose this epidemiological cross-sectional multi-center study is detect 4-week-, 12-month-, lifetime rates comorbid further assess support needs across all major tumor entities in- outpatient oncological health...
This study provides prevalence data of mental disorders (4-week, 1-year, lifetime) and psychological distress in Adolescent Young Adult (AYAs) with cancer.We included an AYA subsample (15 to 39 year olds; diagnosed within the last 5 years) extracted from a larger sample (4.020 cancer patients) who had been recruited for epidemiological across all major tumor entities. Participants were assessed depression screener (PHQ-9). Following that, 50% participants scored below cutoff 9 patients above...
The value of inspiratory muscle training (IMT) in pulmonary rehabilitation chronic obstructive disease (COPD) is unclear. RIMTCORE (Routine Inspiratory Muscle Training within COPD Rehabilitation) randomised controlled trial examined the effectiveness IMT added to rehabilitation. In total, 611 patients (Global Initiative for Chronic Obstructive Lung Disease stage II–IV) received a 3-week inpatient rehabilitation, which 602 were included intention-to-treat analyses. intervention group (n=300)...
Background: We aimed to analyze preferred and perceived levels of patients' involvement in treatment decision-making a representative sample cancer patients.Material Methods: conducted multicenter, epidemiological cross-sectional study with stratified random based on the incidence diagnoses Germany. Data were collected between January 2008 December 2010. Analyses undertaken 2017 2019. included 5889 adult patients across all entities disease stages from 30 acute care hospitals, outpatient...
The randomized INH (Interdisciplinary Network Heart Failure) trial (N = 715) reported that 6 months' remote patient management (RPM) (HeartNetCare-HF) did not reduce the primary outcome (time to all-cause death/rehospitalization) vs usual care (UC) in patients discharged after admission for acute heart failure, but suggested lower mortality and better quality of life RPM group.The Extended (E)-INH investigated effects 18 HeartNetCare-HF on same an expanded population 1,022) followed...