Abstract Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) affects millions of people worldwide. The article aims to review the therapeutic perspective on natural antioxidants, their mechanism action, pharmacokinetics in management and cure COVID‐19/ SARS‐CoV‐2 infection. We conducted a literature search including World Health Organization National Institute guidelines clinical trials registered with ClinicalTrials.gov limited antioxidants COVID‐19 management. Elderly,...

Abstract The aim of this study was to identify the bioactive phytoconstituents present in aqueous extract Nigella sativa and also, evaluate antioxidant antihyperlipidemic activity Wistar rats. LC‐MS/MS analysis assessed for determination different compounds N. extract. Total phenolic flavonoid content were determined by using validated Folin‐Ciocalteu Aluminum chloride colorimetric methods, respectively. in‐vitro in‐vivo rats also evaluated. Preliminary phytochemical screening showed...

INTRODUCTION: Many studies have shown the association of waist circumference, hip ratio and body mass index with type 2 diabetes mellitus. Waist circumference been used as measures central obesity has a measure general obesity. Objective this study is to find out which better for prediction risk mellitus.
 MATERIAL AND METHODS:Total 100 participants confirmed diagnosis DM age group 35-80 years were selected study. Anthropometric measurements like height, weight, (WC) measured (BMI)...

Background: Cassia tora is a traditional herbal medicine has been used as an antihyperlipidemic, anti-inflammatory, anti-diabetic, expectorant, antioxidant effect, etc. Objectives: The aim of this study was to evaluate the anxiolytic and antidepressant effect hydro-alcohol extract in Swiss mice. Methods: Hydro-alcohol for evaluation antidepressant, anxiolytic, biochemical estimation, skeletal muscle relaxant, anoxic tolerance test. Results: showed that, Locomotor activity, there significant...

By Shiva Raj Mishra, Bishal Joshi & 2 more. Global health enterprises need to revitalize local epistemic undo the historical injustices imposed on them in various forms, by liaising with governmental, and non-governmental stakeholders

INTRODUCTION: Postoperative pain management is essential for early mobilization and rehabilitation to enhance recovery reduce morbidity. Ketorolac pethidine are two most common analgesics used in the postoperative setting management.
 MATERIAL AND METHODS: Sixty patients (n=60) of age group 18-60 years who undergone various surgical procedures were divided randomly into groups (T1 T2). T1 received inj. ketorolac 5 mg/kg IM T2 1.5 body weight respectively on 6 hourly basis 48 hours...

Background: Dysmenorrhea, the cramping pain experienced by women during menstruation, can significantly impact their daily lives and academic performance. Mental stress is a potential trigger for dysmenorrhea, but association remains to be precisely determined. This study aims explore prevalence of dysmenorrhea among undergraduate female students at Universal College Medical Sciences investigate its with perceived stress.Methods: A descriptive cross-sectional was conducted Sciences,...

ABSTRACT Medical education is a comprehensive and specialized field that emphasizes the importance of attention for integrating various pieces information, development critical thinking skills applying knowledge effectively. Enhancement attentional abilities essential to keep pace with complicated, commercial social environments. However, sustained challenged in medical students by elements, including rigorous academic curriculum, high levels stress, prevalence digital distractions. This...

Background and objectives: Diabetes mellitus (DM) comprises a group of common metabolic disorders that share the phenotype hyperglycemia. The incidence type 2 DM is rapidly increasing worldwide constitutes major global health problem. various risk factors for development are obesity, ethnicity, sedentary life style, sex, family history, hypertension smoking. However, there now overwhelming evidence from experimental, epidemiological interventional studies obesity factor Type among all...

Introduction: Urinary tract infection is a common bacterial associated with significant morbidity, mortality, and financial burden. This study aimed to identify the causative bacteria, assess their antimicrobial susceptibility patterns evaluate empirical definitive antibiotic therapy for urinary infection. Methods: A hospital-based crosssectional was conducted at outpatient medicine department teaching hospital in Nepal from February 15 July 14, 2022. Two hundred participants positive urine...

Background: ABO and Rh systems are most important types of blood group that should be taken into consideration during transfusion. Many studies have been done across the globe to determine distribution these groups among different strata population. But there very few in Nepali Therefore, this study we aimed find out medical students compare it with other Nepal countries World.
 Methods: This was a retrospective study, containing data medi­cal recorded over period 21 years Department...

INTRODUCTION
 A research paper is a part of academic writing where there gathering information from different sources. It multistep process. Selection title the most important writing. The which interesting should be chosen for purpose. All related gathered and synthesized. After thorough understanding developing title, preliminary outline made maintains logical path its exploration. research, proper work started with collection previous resources then organized points are noted. Then...

INTRODUCTION: Blood groups depend on antigens present the surface of red blood cells. Scientists have discovered at least 30 common and hundreds rare causing antigen-antibody reaction in human These are genetically determined developed fetal life remain unchanged till death. Many group systems identified but ABO Rh more antigenic.
 MATERIAL AND METHODS: In study, we observed 3057 students who studied Universal College Medical Sciences, Bhairahawa, Nepal from 1998 AD to 2019 AD, using...

INTRODUCTION
 Diabetes mellitus is the most common metabolic disease worldwide. Nigella sativa also known as black cumin, an emerging miracle herb with a rich historical and religious background. In present study, we have attempted to study hypoglycemic effect of aqueous extract on diabetes-induced rats.
 MATERIAL AND METHODS
 This preclinical was conducted in Department Pharmacology from August October 2019. this hyperglycemia induced by single intraperitoneal dose 60 mg/kg...

INTRODUCTION 
 Diabetes mellitus (DM) is a metabolic disorder with very high prevalence. Adequate knowledge about diabetes essential for medical students as they are future frontline warriors its management. In the present study, we have attempted to assess of related various aspects DM.
 MATERIAL AND METHODS
 this cross-sectional 445 studying in Universal College Medical Sciences (UCMS), Bhairahawa, Nepal were included. A total 20 self-designed questionnaires regarding DM...

Background: Depression is more common in patients with type 2 Diabetes Mellitus (DM) than pa­tients without DM. The objective of this study was to the effect escitalopram on gly­caemic control diabetic depression. Methods: This longitudinal conducted Universal College Medical Sciences (UCMS), Bhairahawa from September 2019 March 2020. A total 137 visiting internal medicine OPD and diagnosed DM were included. then referred for psychiatric evaluation. Patient Health Questionnaire -9 used...

The global pandemic situation caused by rare viral pneumonia occurs in late December 2019 Wuhan, China, which we now recognize as COVID-19. molecular docking was used to identify potential phytoconstituents of <i>Moringa oleifera</i> and reference drug hydroxychloroquine on SARS-CoV-2 main protein using AutoDock 4.2.6 Auto dock Vina. All the physicochemical bioactive parameters (ADME, toxicity study, receptor interaction, PASS analysis, drug-likeness) were determined different...

INTRODUCTION: Mental health impact of COVID-19 is a well-known entity. Health science students are among the high risk groups for developing mental issues due to lengthy and rigorous studies they undertake. This study aims explore undergraduate Maharajgunj Medical Campus, Nursing Campus during COVID pandemic in Nepal. MATERIAL AND METHODS: A descriptive cross-sectional was conducted from February 2021 July using convenience sampling technique Nepali version DASS-21 campus. RESULTS: Out 164...

Background: ABO and Rh systems are most important types of blood group that should be taken into consideration during transfusion. Many studies have been done across the globe to determine distribution these groups among different strata population. But there very few in Nepali Therefore, this study we aimed find out medical students compare it with other Nepal countries World.
 Methods: This was a retrospective study, containing data medi­cal recorded over period 21 years Department...

Introduction Worldwide pandemic of COVID 19 and its confinement has affected in some way the physical behavioral aspect every individual. Health science students are generally known to have reduced activity decreased sleep duration. During health may adapt different behavior because their knowledge about healthy behaviors. This study aims explore Maharajgunj Medical Campus, Nursing Campus during Nepal. Methods A descriptive cross-sectional was conducted from February 2021 June using...

Background: Diabetes mellitus (DM) is one of the most common systemic diseases encountered by dentists in daily practice. The present study aimed to assess knowledge, attitude, and practice regarding diabetes mellitus. Methods: This cross-sectional was conducted among Nepal from August December 2020. A total 345 throughout country took part this study. set 27 self-designed questions used as tool, which 11 were about seven nine related DM. result expressed frequency percentage. Chi square...