A5077231312- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Tryptophan and brain disorders
- Bipolar Disorder and Treatment
- Stress Responses and Cortisol
- Psychosomatic Disorders and Their Treatments
- Advanced Neuroimaging Techniques and Applications
- Early Childhood Education and Development
- Bullying, Victimization, and Aggression
- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Maternal Mental Health During Pregnancy and Postpartum
- Vestibular and auditory disorders
- Digital Mental Health Interventions
- Hearing, Cochlea, Tinnitus, Genetics
- Hormonal Regulation and Hypertension
- Health disparities and outcomes
- Neural dynamics and brain function
- COVID-19 and Mental Health
- Attention Deficit Hyperactivity Disorder
- Neural and Behavioral Psychology Studies
- Neuroscience and Neuropharmacology Research
- Diet and metabolism studies
Northwestern University
2016-2024
Harvard University
2024
Universidade Estadual de Londrina
2023
Health Innovations (United States)
2021
Northwestern University
2020
National Institutes of Health
2017
Universidad Autónoma del Estado de Hidalgo
2009
University of Chile
2007
Hospital General Universitario Gregorio Marañón
2003
University of North Dakota
1993
Peer victimization predicts the development of mental health symptoms in transition to adolescence, but it is unclear whether and how parents school environments can buffer this link.
Neighborhood deprivation adversely effects neurodevelopment and cognitive function; however, mechanisms remain unexplored. could be particularly impactful in late childhood/early adolescence, neural regions with protracted developmental trajectories, e.g., prefrontal cortex (PFC). The Adolescent Brain Cognitive Development (ABCD) study recruited 10,205 youth. Geocoded residential history was used to extract individual neighborhood characteristics. A general ability index MRI scans were...
Converging evidence suggests that hippocampal subregions subserve different functions, and are differentially affected by psychosis illness progression. Despite this fact, studies have not often studied cross-sectionally across the spectrum. Furthermore, little is known about associations between subregion volumes hippocampus-mediated cognition.
BackgroundAssessing dimensions of neighborhoods could aid identification contextual features that influence psychopathology in children and contribute to uncovering mechanisms underlying these associations. MethodThe ABCD sample included 11,868 participants aged 9-10 from 21 U.S. sites. Mixed effect structural equation models estimated associations neighborhood threat deprivation with symptoms indirect effects. Hypothesized emotion processing (adaptation emotional conflict, task-active ROIs...
ObjectiveNeighborhood adversity predicts mental health and cognitive outcomes, but little is known about structural factors that may buffer these links. The current study addresses this gap by assessing the role of protective in association neighborhood deprivation, threat, segregation with psychopathology symptoms outcomes. MethodLinear mixed models were run ABCD sample 11,868 participants to test associations Area Deprivation Index (ADI; deprivation), crime (threat), dissimilarity...
BackgroundAssessing dimensions of neighborhoods could aid identification contextual features that influence psychopathology in children and contribute to uncovering mechanisms underlying these associations. MethodThe ABCD sample included 11,868 participants aged 9-10 from 21 U.S. sites. Mixed effect structural equation models estimated associations neighborhood threat deprivation with symptoms indirect effects. Hypothesized emotion processing (adaptation emotional conflict, task-active ROIs...
Adolescence is among the most vulnerable period for emergence of serious mental illnesses. Addressing this vulnerability has generated interest in identifying markers risk symptoms and opportunities early intervention. Physical fitness been linked to psychopathology may be a useful marker target New wearable technology made assessing behavior more practical while avoiding recall self-report bias. Still, questions remain regarding clinical utility physical metrics health, both...
The National Institute of Mental Health Research Domain Criteria's (RDoC) has prompted a paradigm shift from categorical psychiatric disorders to considering multiple levels vulnerability for probabilistic risk disorder. However, the lack neurodevelopmentally-based tools clinical decision-making limited RDoC's real-world impact. Integration with developmental psychopathology principles and statistical methods actualize implementation RDoC inform neurodevelopmental risk. In this conceptual...
There has been no systemic investigation of the effects training on endurance at different high-intensity work rates in patients with COPD to date.We wanted determine intense tolerance several and establish relationship between power (WR) its tolerable duration (t) (t = W'/(WR - CP), being W', curvature constant, thought be reflective anaerobic energy availability and/or uncomfortable sensations associated exercise, CP critical power.We studied 27 patients: age 62 +/- 5 years; FEV(1) 1.2 0.2...
Abstract Background Motor abnormalities are strong transdiagnostic indicators of psychopathology risk that reflect emerging neural network abnormalities. Indeed, motor signs, such as slowing and agitation, widely recognized core features both psychosis depression. However, it is unclear whether these shared or distinct etiology. Methods A sample 11 878 adolescents completed self-reported clinical measures rated psychotic-like experiences (PLEs) Familial for the presence signs were drawn from...
Motor abnormalities, such as psychomotor agitation and retardation, are widely recognized core features of depression. However, it is not currently known whether motor abnormalities connote risk for Using data from the Adolescent Brain Cognitive Development (ABCD) Study, a nationally representative sample youth (N = 10,835, 9–11 years old), present paper examines associated with 1) depression symptoms in early adolescence, 2) familial (familial loading), 3) future symptoms. abnormality...
Abstract Discrimination has been associated with adverse mental health outcomes, though it is unclear how early in life this association becomes apparent. Implicit emotion regulation, developing during childhood, a foundational skill tied to range of outcomes. regulation yet be tested as an process for illness symptoms that can often emerge sensitive developmental period. Youth aged 9–11 were recruited the Adolescent Brain Cognitive Development (ABCD) study. Associations between...
Psychotic disorders are highly debilitating with poor prognoses and courses of chronic illness. In recent decades, conceptual models have shaped understanding, informed treatment, guided research questions. However, these classically focused on the adolescent early adulthood stages immediately preceding onset while conceptualizing infancy through all childhood as a unitary premorbid period. addition, paid limited attention to differential effects types stress; contextual factors such local,...