In this paper, we study the mathematical model of interaction cancer cells and immune system presented Castiglione Piccoli. As between is weak, when body begins to decrease, get stronger increase rapidly. Helper CD4+ T cytotoxic CD8+ cells, dendritic cytokine interleukin-2 (IL-2) are involved in competition living body. can be seen literature, since have memory structure, fractional models describe struggle give more meaningful results than classical as closer reality. The main motivation...

In this research, we examine the nonsingular memory effect when implementing Atangana–Baleanu (AB) fractional derivative in Caputo sense to Hepatitis C virus (HCV) model. For purpose, first, sufficient conditions for existence and uniqueness of solutions under AB model are expressed proved. Therewithal, order show response on system dynamics practically, a new version predictor–corrector method is used with newly estimated parameters from literature. Finally, provide some simulations results.

Although nasal polyps are one of the most frequent diseases, their etiopathogenesis remains unclear.Since eosinophils main inflammatory cells in substantial proportion polyp tissues, they considered potentially responsible for and prognosis disease. Aim this study was to investigate relation between mucosal peripheral eosinophilia with disease severity polyps.The included 53 patients who underwent endoscopic sinus surgery. Preoperative Lund-MacKay computed tomography (CT) scores Lund-Kennedy...

To assess the prognostic value of Ki-67, p27, and p53 immunoreactivity in human gastric cancer. Materials methods: A total 84 patients with cancer participated our study. We categorized tumors as intestinal diffuse types, reference to Lauren's classification. were correlated patient's age, tumor type, grade, lymph node status, extent invasion, tumor-node-metastasis (TNM) stage, survival. Results: Decreased expression p27 (50% positivity cells) determined 41 (48.8%) 29 (36.9%) specimens,...

Different medical therapies are employed in acute lung injury (ALI) but there is still a debate about the efficacy of these drugs. Among steroids clinically applied and bosentan experimentally studied. The aim this study was to evaluate two drugs treat inflammation ALI by histopathological comparison. five experimental groups (n = 5 per group) were: saline control (Group I); lipopolysaccharide (LPS) + II); LPS dexamethasone III); 50 mg/kg IV); 100 V). Bosentan administered orally one hour...

Ulcerative colitis (UC) is an inflammatory bowel disease of unknown etiology for which effective treatments are lacking. Scutellarin a flavonoid with anti-apoptotic, antioxidant and anti-inflammatory effects. We investigated the possible protective effects scutellarin on UC induced by acetic acid in rats. used five groups male rats: control, scutellarin, UC, + sulfasalazine. Colonic mucosal inflammation was evaluated microscopically. Malondialdehyde (MDA), superoxide dismutase (SOD)...

The most important side effect of gentamicin (GM) is nephrotoxicity. p-Coumaric acid (PCA) a phenolic compound that scavenges free radicals, reduces fibrosis, and tissue damage. This study investigates the protective PCA on damage kidney function in gentamicin-induced nephrotoxicity (GIN). Thirty-five rats were separated into five groups each group contained seven animals: control group, ethanol GM + group. At end seven-day treatment, sacrificed after blood samples taken. While serum urea,...

In this study it is aimed to contribute in determination of geographic distribution Hydatid Cysts Turkey and emphasize the clinic chaos cases found various localizations, by indicating prevalence our region.It evaluated that diagnosed as Atatürk University Medical Faculty Pathology Depatment/Erzurum laboratories between 2003-2013; terms their age, gender, organ involvement histopathologic detail.In study, 459 are defined. The most common localizations determined liver (n:280, 61%) lung...

To evaluate serum levels of high-sensitivity C-reactive protein (hs-CRP) in chronic gastritis patients to predict Helicobacter pylori (HP) infection, inflammatory activity, and precancerous lesions.A total 811 with upper gastrointestinal symptoms histopathological diagnosis were enrolled the study. On endoscopy, five gastric biopsies taken according Modified Sydney protocol, which stained hematoxylin & eosin Giemsa.HP infection was found 28.6% patients, being significantly more common...

To evaluate the protective effect of Nigella sativa oil (NSO) on myocardium in streptozotocin-induced diabetic rats.Thirty-two 7-8-week-old female Wistar albino rats (300-350 g) were equally divided into 4 groups: nondiabetic untreated animals (control), diabetes mellitus (DM), NSO, and DM+NSO groups. For induction diabetes, 45 mg/kg streptozotocin was applied to DM groups as a single intraperitoneal dose. NSO (400 mg/kg) orally administered through an intragastric catheter once day over 21...

Background: Owing to the variability of histopathological features and biological behaviour in gastric carcinoma, a great number categorisation methods such as classical histopathologic grading, Lauren classification, TNM staging system newly presented Goseki grading method are used by pathologists other scientists. In our study, we aimed investigate whether grade tumour location have an effects on survival cancer cases. Materials Methods: Eighty-four patients with adenocarcinoma were...

<br>Juvenile ossifying fibroma (JOF) is a rare benign tumor of the craniofacial bones differing from other fibro-osseous lesions in terms early age onset, aggressive clinical behavior, and high recurrence rate. Histopathologically, it divided into two as trabecular JOF (TrJOF) psammomatoid (PsJOF). In PsJOF, psammoma-like spherical ossicles constitute pathognomonic histopathological images, whereas TrJOF has trabeculae fibrillary osteoid woven bone. Despite histopathologic separation, both...

Background and Objectives: The purpose of this study was to apply histopathological immunohistochemical methods compare the protective efficacy melatonin N-acetylcysteine (NAC) application in rats with experimental brain ischemia/reperfusion (I/R) injury induced through occlusion middle cerebral artery (MCA), evaluate effect their combined use. Materials Methods: Forty-one young adult male Wistar albino were divided into five groups-control (n = 8), I/R group NAC + 9). Results: All scores...

HPV causes specific cell-mediated immunity in the cervix. Mononuclear cells such as helper T (CD4+), cytotoxic (CD8+), and dendritic play a critical role initiation of HPV-specific immune response destruction virus-infected cervical epithelial cells. The programmed cell death ligand 1 (PD-L1) gene encodes an inhibitory receptor overexpression PD-L1 inhibits T-cell activation cytokine production. aim this study was to investigate expression tissue its correlation with clinicopathological...

Cervical cancer is the ninth most common among females in Turkey. smear a routine screening test used for detection of cervical abnormalities and also it detects certain infections cervix.To analyze results our clinic order to determine frequent pathology women North Eastern Anatolia Region Turkey.In retrospective study design, 8,495 cytology cases diagnosed at Pathology Department Regional Education Research Hospital Erzurum over last one half years extending from August 2012 December 2013...

Objective . To evaluate the effect of streptozotocin-induced experimental diabetes mellitus on p16, p53, Ki67, and Bcl2 expressions histopathological changes in tongue rats. Material Methods Twenty-two adult female Sprague-Dawley rats were used. The randomly divided into 2 groups (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>14</mml:mn></mml:math>) as control (C)...

Objective The aim of this study was to investigate the immunohistochemical stain profiling adipocytic tumors. Methods From our archive files between years 2012-2018, excised, formalin-fixed and paraffin-embedded tumors were retrospectively screened 61 subjects selected. gender, age, tumor location diameter evaluated. cases investigated in terms p16, CD34, MDM2 expression clinicopathological information. Results Of patients included study, we found that 2 had hibernoma, 4 lipoblastoma, 14...

Background: Although nasal polyps are one of the most frequent diseases, their etiopathogenesis remains unclear. Since eosinophils main inflammatory cells in substantial proportion polyp tissues, they considered potentially responsible for and prognosis disease. Aim this study was to investigate relation between mucosal peripheral eosinophilia with disease severity polyps. Methods: The included 53 patients who underwent endoscopic sinus surgery. Preoperative Lund-MacKay computed tomography...

Background: Different medical therapies are employed in acute lung injury (ALI) but there is still a debate about the efficacy of these drugs. Among steroids clinically applied and bosentan experimentally studied. The aim this study was to evaluate two drugs treat inflammation ALI by histopathological comparison. Methods: five experimental groups (n = 5 per group) were: saline control (Group I); lipopolysaccharide (LPS) + II); LPS dexamethasone III); 50 mg/kg IV); 100 V). Bosentan...