There has been an increased incidence of macrosomic newborns in the world and most are born from non-GDM pregnant women. The objective this study was to determine frequency associated risk factors fetal macrosomia women.A total 4246 consequtive women who had no GDM included population. Data collected hospital database Balikesir State Hospital between January 2014 2015. Statistical analysis carried out using independent samples t-test chi-squared test. Logistic regression used relationships...

Women with polycystic ovary syndrome are more likely to suffer from obesity, insulin resistance, and chronic low-grade inflammation. In fact, the excessive activation of monocytes exacerbates oxidative stress However, high-density lipoprotein cholesterol neutralizes pro-inflammatory pro-oxidant effects monocytes. The aim this study is investigate whether monocyte counts ratio can predict inflammatory condition in patients syndrome.In cross-sectional study, a total 124 women (61 them 63...

Abstract Background Endometriosis is an estrogen-dependent inflammatory disease that often causes infertility and chronic pelvic pain. Although endometriosis known as a benign disease, it has demonstrated characteristics of malignant neoplasms, including neoangiogenesis, tissue invasion, cell implantation to distant organs. Octamer-binding protein 4 (Oct-4) molecular marker for stem cells plays essential role in maintaining pluripotency self–renewal processes various types tissues. CD44...

Introduction: Preeclampsia is a systemic inflammatory disorder and major cause of maternal fetal mortality. Fractalkine (CX3CL1) member the chemokine family with multiple functions in organization immune system. It up-regulated disorders. During inflammation, fractalkine enhances tissue destruction cell invasion. We aimed to investigate alteration placental tissues pregnant women preeclampsia correlation this clinicopathological variables.Materials methods: Alteration specimens was...

Borderline ovarian tumours (BOTs) are characterised histologically by a low degree of cellular proliferation and nuclear atypia in the absence infiltrative growth or stromal invasion. Surgical treatment has been crucial component BOT therapy. decisions established intraoperatively via frozen section. We evaluated accuracy section diagnosis. The rate correct diagnosis, underdiagnosis overdiagnosis BOTs with sections was 78%, 17% 5%, respectively. sensitivity positive predictive values for...

Objective: The aim of the study was to determine effects age, gender and season on vitamin D status in healthy urban population at reproductive age. Also, we investigated distribution into different groups regarding 25(OH)D levels. Methods: Serum levels 21,317 participants: 5,364 men (25.1%) 15,953 women (74.8%), aged between 18-45 years, applying two medical centres for check-up located same city were retrospectively analyzed. Group I consisted 14,720 participants (11,257 3,463 men) first...

SUMMARY OBJECTIVE: Fetal vascular malperfusion is associated with poor perinatal outcomes in women preeclampsia and gestational diabetes mellitus. The aim of this study was to determine the association between fetal score syncytiotrophoblast basement membrane thickness clinicopathological variables, such as developing METHODS: This retrospective cohort included 65 pregnant participants (34 mellitus 31 controls) January 2019 2022. Gestational diagnosed ≥2 4 elevated values on a 3-h, 100-g...

The effects of metformin on a testicular torsion injury in adolescent rat testis after I/R were evaluated the present study. Forty rats divided into five groups with eight per group: control group; sham-operated an ischaemia group, where was applied for 4 hr and examined immediately detorsion; + M (300 mg/kg) administration added to identical procedures used group. Spermatogenesis, basal membrane integrity cleaved caspase-3 expression assessed. group had significantly higher Johnsen score...

HPV causes specific cell-mediated immunity in the cervix. Mononuclear cells such as helper T (CD4+), cytotoxic (CD8+), and dendritic play a critical role initiation of HPV-specific immune response destruction virus-infected cervical epithelial cells. The programmed cell death ligand 1 (PD-L1) gene encodes an inhibitory receptor overexpression PD-L1 inhibits T-cell activation cytokine production. aim this study was to investigate expression tissue its correlation with clinicopathological...

Screening Cytomegalovirus Infections in First Trimester of Gestation among High Prevalence Population

To compare the live birth rates and moderate/severe ovarian hyperstimulation syndrome (OHSS) of 2 different approaches using gonadotropin-releasing hormone (GnRH) agonist triggering in high responder women. Methods: A retrospective cohort study was performed to evaluate intracytoplasmic sperm injection (ICSI) embryo transfer (ET) outcomes women who underwent ovulation induction with a GnRH antagonist protocol between April 2011 March 2015. In group 1 (n=74), used for concomitant use 1500 IU...

Endometriosis is defined as the presence of functional endometrial tissues outside uterine cavity. Ovarian endometrioma most common type endometriosis. It an estrogen-dependent inflammatory disease that frequently causes infertility and chronic pelvic pain. Cyclophilin A (CyPA) secreted from various types cells in response to stimuli. Many previous studies have shown increased expression and/or heightened plasma levels CyPA exacerbates inflammation. The aim this study evaluate...

Our aim in this study was to investigate morning blood pressure surge (MBPS) patients of reproductive age with polycystic ovary syndrome (PCOS) and its relation insulin resistance (IR).Fifty-three PCOS without additional illness were included the study. Forty-two age-matched subjects selected as control group. All underwent 24-h monitoring. Patients illnesses, drug users, smokers, alcohol abusers excluded. Blood insulin, fasting glucose, lipid profile, hormone profile measured. Insulin...

In this study, it is aimed to compare the diagnostic accuracy of preoperative magnetic resonance imaging (MRI) and intraoperative frozen section in determining depth myometrial invasion patients with endometrioid type endometrial cancer. Retrospective evaluation 69 cancer who underwent MRI subsequently frozen-section surgical staging between February 2004 September 2011. Surgical was performed according 2009 FIGO classification. Final histopathological examination accepted as standard...

GirişTüm dünyada önemli bir halk sağlığı sorunu olan Human Papilloma Virus (HPV)'ların özellikle belirli tiplerinin servikal kanser gelişme riskini ölçüde artırdığı bilinmektedir.Servikal kanserin erken teşhisinde ve önlenmesinde kişideki HPV enfeksiyonunun etken tipinin saptanması önem taşımaktadır (1).Şimdiye kadar 200'ün üzerinde tipi tanımlanmıştır.HPV tipleri ÖZET Amaç: Serviks kanseri tüm sağlık sorunudur.Serviks kanserinin teşhisinde, (HPV) varlığının genotipinin belirlenmesi...

Synchronous primary gynecological cancers have been reported to be seen rarely in the literature. In this report, we aimed describe a 51-year-old patient with coexistence of villoglandular papillary adenocarcinoma cervix uteri and Brenner tumor right ovary. She successfully underwent radical hysterectomy, bilateral salphing-oopherectomy pelvic para-aortic lymphadenectomy.