Background: Oncostatin M, a novel adipokine, plays role in oogenesis, lipogenesis, and inflammation may contribute to polycystic ovary syndrome pathogenesis related metabolic problems. Adipokines are believed developing its accompanying parameters, such as dyslipidemia, insulin resistance, cardiovascular diseases. Methods: In this case–control study, the patients were grouped 1:1 ratio into either (n = 32) or control group 32). Serum levels of fasting glucose, insulin, C-reactive protein,...

Round ligament varicosity (RLV) is rare and almost all cases are pregnant women. RLV appears as a unilateral or bilateral groin swelling. Pain tenderness may present. Clinical evaluation inadequate for exact diagnosis because inguinal hernia has similar findings. Ultrasonography (US) essential when swelling detected in woman. We present gray scale US colour Doppler findings of 32-week woman with RLVs at the canal, parauterine area myometrium.

Ovulation is regulated by extracellular signal-regulated kinase-1 (ERK-1) and ERK-2 signaling mechanisms, ERK-1/2 kinases modulates the function of most LH-regulated genes. Defective ERK kinase that secondary to a genetic problem contributes both ovulatory dysfunction metabolic problems in polycystic ovary syndrome (PCOS). We planned investigate ERK-1 gene polymorphisms PCOS for first time Turkish population.One hundred two patients 102 healthy controls were recruited this patient control...

The aim of this study is to evaluate the effects sildenafil citrate on cisplatin-induced ovarian toxicity. Thirty-two female rats were divided into four groups. Group 1: saline control; group 2: cisplatin; 3: citrate; and 4: cisplatin plus group. In groups 2 4, injected with 5 mg/kg intraperitoneally (i.p.). 3 1.4 i.p. ovaries removed two weeks later in all Histopathologic examination, follicle counting classification performed. expression anti-Müllerian hormone (AMH) was detected...

Neutrophil gelatinase-associated lipocalin (NGAL, also known as lipocalin-2) is an acute-phase protein expressed in many tissues and plays a role cell proliferation, regulation, epithelial-mesenchymal transformation. Therefore, this study aimed to investigate serum NGAL levels endometrioma tissue expression women with endometriosis. This cross-sectional was conducted at university hospital. The group included 36 who underwent ovarian cystectomy for endometrioma, which compared control (n =...

Primary ovarian leiomyoma is a rare benign tumour of the ovary seen in women between 20 and 65 years old. It usually diagnosed incidentally during pelvic examination or pathologic after surgery.We describe case unilateral, leiomyoma. Transvaginal ultrasonography magnetic resonance imaging (MRI) revealed right adnexial mass. Unilateral salpingo-oophorectomy was performed, histological arising primarily ovary. The diagnosis confirmed immunohistochemically.The may be asymptomatic manifest with...

Polycystic ovary syndrome is known to be the most common hormonal disorder in women of reproductive age. Current evidence shows that regulatory proteins secreted from adipose tissue called adipokines may have a role polycystic syndrome. We planned investigate endotrophin has never been researched before and its correlation with other metabolic parameters such as adiponectin ghrelin patients syndrome.Forty-three (n: 43) 43 control group were enrolled this cross-sectional study. Serum levels...

Polycystic ovary syndrome (PCOS) is a multifactorial disease characterised by chronic inflammation. We aimed to investigate an association between IL-1A and IL-6 gene polymorphisms both hormonal/biochemical parameters levels of IL-6. A total 103 women diagnosed with PCOS according ESHRE/ASRM criteria were investigated. The patients divided into two groups as obese non-obese. genes well analysed in the same groups. Serum found increase non-obese However, there was no level polymorphism....

The involvement of the ovary by malignant lymphoma is a well-known late manifestation disseminated nodal disease. Primary ovarian rare. We herein describe case primary diffuse large B-cell involving unilateral in 38-year-old woman which was detected incidentally. Preoperative ultrasonic imaging showed 46∗42 mm heterogeneous cystic mass. Laparotomy revealed that left adnexal mass and salpingo-oophorectomy performed. current diagnosis determined after immunostaining. patient treated with...

Nesfatin-1, encoded by the nucleobindin-2 (NUCB2) gene, is an anorexigenic protein related to energy metabolism, obesity, and insulin resistance. The aim of this study was evaluate NUCB2 gene polymorphism (rs757081) its association with serum levels nesfatin-1 in obese non-obese women polycystic ovary syndrome (PCOS). In population, we analyzed 60 patients PCOS 26 age-matched healthy as controls. were divided into two groups based on body mass index (BMI): group (n = 28) or 32). genotyped...

Accessory Spleen (AS) is a very rare entity and usually near the spleen's hilum in tail of pancreas. Pelvis reported as an atypical localization. AS may be formed during embryonic life, they rise from left side dorsal mesogastrium result imperfect fusion separate splenic masses. We report case presenting adnexal mass middle-aged woman. Transvaginal ultrasonography magnetic resonance imaging (MRI) revealed adnexial mass. Laparatomy was performed, histological examination that resected tissue....

The aim of the present study was to evaluate effects progesterone (PG) against ovarian ischemia-reperfusion (I/R) injury through evaluation biochemical and histopathologic parameters.Twenty-one female Wistar albino rats were divided into three groups. Group 1: Sham; group 2: I/R; 3: I/R+PG (8 mg/kg). PG administered intraperitoneally in 3, 30 minutes before a detorsion operation. Ovarian I/R evaluated serum tissue by using parameters including malondialdehyde (MDA), total antioxidant status...

Aim: Pregnancy, birth and post-partum period is an important process in which many physiological, psychological social changes are experienced by mothers fathers. Pregnancy also one of the periods when sexuality most affected, sexual dysfunctions common during this period. The aim study to investigate myths pregnant women their partners.
 Material Method: This research was conducted university hospital Turkey with a total 128 participants, 77 51 spouses who agreed participate.
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Carbonic anhydrases (CAs), a group of metalloenzymes, are involved in numerous physiological and pathological processes such as acid-base balance, gluconeogenesis, lipogenesis, ureagenesis, electrolyte secretion various tissues, bone resorption calcification, tumorigenicity. In the current study, we aimed to determine compare possible alterations activity carbonic anhydrase I (CA I) II II) isozymes by using estrogens progestagens female smokers nonsmokers.Blood samples from 30 smoker...

The aim of the study is to investigate effects interleukin-6 (IL-6) blocker tocilizumab in a hyperstimulated rat model and compare it with ranibizumab, gonadotropin-releasing hormone antagonist (GnRHA), cabergoline. Forty-seven rats were randomly divided into following seven groups: Group 1: OHS; 2: OHS+ GnRHA; 3: OHS + ranibizumab; 4: cabergoline; 5: low-dose (TL); 6: high-dose (TH); 7: sham. Ovarian weight was significantly lower only ranibizumab group than group. Estrogen levels GnRHA...

Objectives: ADAMTS (A Disintegrin And Metalloproteinase with ThromboSpondin repeats) proteinases, which are released outside the cell (soluble) have very critical roles in damage and repair of extracellular matrix (ECM) processes. Our aim was to analyse ADAMTS-1 ADAMTS-9 were member gene family metalloproteinases that might had been involved cytokines-mediated etiopathogenesis endometriosis. Methods: A case-control study performed an university hospital. Thirty-four patient endometriosis...

Screening Cytomegalovirus Infections in First Trimester of Gestation among High Prevalence Population

The chronic course of endometriosis suggests that the immune system may play a role in its aetiology. There be resistance to cell lysis, as well an defect underlying endometriosis. Granzyme B is serine protease secreted by Natural Killer (NK) cells and cytotoxic T lymphocytes during cellular response can induce apoptosis. aim this study was evaluate relationship between both levels gene polymorphisms patients. Women ages 20 – 45 were included study. patients divided into two groups: those...

Russell bodies are prominent eosinophilic inclusions seen in the cytoplasm of plasma cells and sometimes outside cell. There very few publications available English literature on Body Cervicitis. Our case is a 40 year old female patient with positive screening test for HPV DNA. The cervical surface epithelium biopsy specimens obtained from cervix completely have eroded intense vesicular eccentric nuclei large containing focal Body. infiltration dense were observed. fourth literature. rare...