A5102881497- Osteoarthritis Treatment and Mechanisms
- Cancer-related molecular mechanisms research
- Veterinary Orthopedics and Neurology
- Circular RNAs in diseases
- Peroxisome Proliferator-Activated Receptors
Zhangqiu City People's Hospital
2014-2019
Jining Medical University
2019
Purpose: Accumulating evidence suggests that microRNA-145 (miR-145) plays an important role in osteoarthritis (OA), which is a chronic progressive joint disease.Long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) promotes metastasis cancers and functions as sponge for miR-145.However, the of MALAT1/miR-145 OA pathogenesis has not yet been elucidated. Materials Methods:The expression MALAT1 miR-145 was examined by quantitative real-time PCR; interaction between...
Animal models played an important role in osteoarthritis studies. Here, the complete mitochondrial genome sequence of Guinea pig was reported for first time. The total length mitogenome 16,797 bp. It contained typical structure, including two ribosomal RNA genes, 13 protein-coding 22 transfer genes and one non-coding control region (D-loop region). overall composition estimated to be 34.9% A, 26.1% T, 26.0% C 13.0% G showing A-T (61.0%)-rich feature. This will provide new genetic resource...