A5072140760- Synthesis and biological activity
- Natural product bioactivities and synthesis
- Bioactive Compounds and Antitumor Agents
- Synthesis and Biological Evaluation
- Synthesis of Organic Compounds
- Click Chemistry and Applications
- Cancer therapeutics and mechanisms
- Phytochemistry and Biological Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Phytochemical compounds biological activities
- Pharmacological Effects of Medicinal Plants
- Drug-Induced Hepatotoxicity and Protection
- Hormonal and reproductive studies
- SARS-CoV-2 and COVID-19 Research
- Sperm and Testicular Function
- Essential Oils and Antimicrobial Activity
- Sesquiterpenes and Asteraceae Studies
- Sexual function and dysfunction studies
- Natural Antidiabetic Agents Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Toxin Mechanisms and Immunotoxins
- Medicinal Plants and Neuroprotection
- Folate and B Vitamins Research
- Plant-derived Lignans Synthesis and Bioactivity
- Prenatal Screening and Diagnostics
Indraprastha Apollo Hospitals
2005-2025
All India Institute of Medical Sciences
2002-2024
Weill Cornell Medicine
2020-2024
Cornell University
2020-2024
Central Institute of Medicinal and Aromatic Plants
2023
Indian Institute of Integrative Medicine
2010-2020
Academy of Scientific and Innovative Research
2014-2015
Council of Scientific and Industrial Research
2003-2015
University of Jammu
2015
University of Maroua
2014
The present study reports the phytochemical profiling, antimicrobial, antioxidant, and anticancer activities of Bauhinia variegata leaf extracts. reducing sugar, anthraquinone, saponins were observed in polar extracts, while terpenoids alkaloids nonpolar ethanol Total flavonoid contents various extracts found range 11-222.67 mg QE/g. In disc diffusion assays, petroleum ether chloroform fractions exhibited considerable inhibition against Klebsiella pneumoniae. Several other also showed...
Annona muricata (A. muricata) is widely distributed in Asia, Africa and South America. Different parts of this plant are used to treat several diseases Cameroon. The aim study determine the vitro anti-proliferative effects apoptotic events A. extracts on HL-60 cells as well quantify its phenols content. cell viability was measured by using 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay while changes morphology cells, membrane mitochondrial potential (MMP) cycle...
A Japan Society of Clinical Oncology (JSCO)-hosted expert meeting was held in on 27 October 2019, which comprised experts from the JSCO, Japanese Medical (JSMO), European for (ESMO), American (ASCO), and Taiwan (TOS). The purpose to focus what we have learnt both microsatellite instability (MSI)/deficient mismatch repair (dMMR) biomarkers predicting efficacy anti-programmed death-1 (PD-1)/programmed death ligand-1 (PD-L1) immunotherapy, neurotrophic tyrosine receptor kinase (NTRK) gene...
Abstract In the Indian traditional system of medicine Withania somnifera Dun. is widely regarded as Ginseng. A new withanolide‐free hydrosoluble fraction was isolated from roots and evaluated for putative antistress activity against a battery tests to delineate this fraction. The latter exhibited significant in dose‐related manner (Singh et al. , 2001) further studied chemical physical induced stress rats mice. extract root (a commercial preparation available locally) also used compare...
Tumor angiogenesis is a validated target for therapeutic intervention, but agents that are more disease selective needed. Here, we report the isolation of secalonic acid-D (SAD), mycotoxin from novel source exhibits potent antiangiogenic antitumor activity. SAD inhibited multiple HIF1α/VEGF-arbitrated dynamics as scored in human umbilical vascular endothelial cells and MCF-7 breast tumor xenografts. Similarly, suppressed VEGF-induced microvessel sprouting rat aortic ring blood vessel...
Endophytes, which reside in plant tissues, have the potential to produce novel metabolites with immense benefits for health industry. Cytotoxic and antimicrobial activities of endophytic fungi isolated from Bacopa monnieri (L.) Pennell were investigated. Endophytic monnieri. Extracts liquid cultures tested cytotoxicity against a number cancer cell lines using MTT assay. Antimicrobial activity was determined micro dilution method. 22% examined extracts showed potent (IC50 <20 μg/ml) cytotoxic...