- Cancer-related molecular mechanisms research
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Wound Healing and Treatments
- RNA Interference and Gene Delivery
- MRI in cancer diagnosis
- Bee Products Chemical Analysis
- Seaweed-derived Bioactive Compounds
- Growth Hormone and Insulin-like Growth Factors
- Ferroptosis and cancer prognosis
- Intraocular Surgery and Lenses
- RNA modifications and cancer
- Retinal Development and Disorders
- Cytomegalovirus and herpesvirus research
- Advanced Computational Techniques and Applications
- Renal Transplantation Outcomes and Treatments
- Cancer Research and Treatments
- Biological and pharmacological studies of plants
- Cancer, Hypoxia, and Metabolism
- Medicinal Plant Pharmacodynamics Research
Affiliated Eye Hospital of Wenzhou Medical College
2022-2023
Wenzhou Medical University
2022-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
University of Shanghai for Science and Technology
2022
Shanghai University of Medicine and Health Sciences
2022
175th Hospital of People's Liberation Army
2017
Xiamen University
2017
Tianjin University of Science and Technology
2007
Guangdong Medical College
2005
Dopamine is a key neurotransmitter in the signaling cascade controlling ocular refractive development, but exact role and site of action dopamine D1 receptors (D1Rs) involved myopia remains unclear. Here, we determine whether retinal D1Rs exclusively mediate effects endogenous systemically delivered D1R agonist or antagonist mouse form deprivation (FDM) model. Male C57BL/6 mice subjected to unilateral FDM unobstructed vision were divided into following four groups: one noninjected three...
To learn more about the locations of dopamine D2 receptors (D2Rs) that regulate form-deprivation myopia (FDM), using different transgenic mouse models.One eye D2R-knockout (KO) mice and wild-type littermates was subjected to four weeks monocular FDM, whereas fellow served as control. Mice in both groups received daily intraperitoneal injections either D2R antagonist sulpiride (8 µg/g) or vehicle alone. FDM also induced retina- (Six3creD2Rfl/fl) fibroblast-specific (S100a4creD2Rfl/fl) D2R-KO...
Recent studies have identified a role for ALKBH7 in the occurrence and progression of cancer, this protein is related to cellular immunity immune cell infiltration. However, prognostic immunotherapeutic value different cancers not been explored. In study, we observed high expression 17 low 5 compared paired normal tissues. Although did correlate relatively significantly with clinical parameters age (6/33), sex (3/33) stage (3/27) studied, results survival analysis reflect pan-cancer ALKBH7....
Currently, developing therapeutic strategies for chondrosarcoma (CS) remains important. Sennoside A (SA), a dianthrone glycoside from Senna and Rhubarb, is widely used as an irritant laxative, weight-loss agent, or dietary supplement, which possesses various bioactive properties such antiobesity, hypoglycemic activities. For the first time, our results suggested that cell proliferation metastasis were inhibited by SA in CS SW1353 cells. induced growth arrest inhibiting proliferation. The...
Oxytropis falcata has long been used to treat inflammation, sores, and bleeding in Tibet. However, the burn remedy underlying molecular mechanisms are not well understood. This study is aimed at assessing effect of falcate gel (OFG) on deep second-degree rats exploring its mechanism. Wistar with were treated OFG silver sulfadiazine. Immunohistochemical detections for EGF VEGF performed, ELISA EGF, VEGF, p38, IL-1β serum determined. Rats (25, 50 g/kg) consisted major...