A5090468105- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
- Pharmaceutical industry and healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Urinary Bladder and Prostate Research
- Prostate Cancer Treatment and Research
- Healthcare Policy and Management
- Pharmaceutical Economics and Policy
- Urological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Opioid Use Disorder Treatment
- Health and Medical Research Impacts
- Radiation Dose and Imaging
- Urinary Tract Infections Management
- Sarcoma Diagnosis and Treatment
- Pelvic floor disorders treatments
- Ureteral procedures and complications
- Healthcare cost, quality, practices
- Testicular diseases and treatments
- Pain Management and Opioid Use
- Pharmaceutical studies and practices
- Radiomics and Machine Learning in Medical Imaging
- Global Cancer Incidence and Screening
- Anesthesia and Pain Management
University of Rochester Medical Center
2021-2025
Urology Associates
2024
UPMC Health System
2022
University of Rochester
2021-2022
University of Pittsburgh Medical Center
2015-2021
University of Pittsburgh
2015-2021
SRI International
2021
Shadyside Hospital
2020
Seattle University
2020
Memorial Sloan Kettering Cancer Center
2019
Clinical trials of drugs, procedures, and other therapies play a crucial role in advancing medical science by evaluating the safety, efficacy, optimal use interventions. The design implementation these have evolved significantly over time, reflecting advancements medicine, ethics, methodology. Early historical examples, such as King Nebuchadnezzar II’s his captives’ dietary experiment Ambroise Paré’s treatment gunshot wounds, laid some foundational principles trial design. momentum clinical...
379 Background: Hematological toxicities are common with radiation therapy (RT), particularly pelvic RT, which affects nearly 50% of total body hematopoiesis. This study evaluates the impact RT on hematological in pediatric patients genitourinary rhabdomyosarcoma (GU-RMS). Methods: Following permission, a secondary analysis was conducted 488 subjects intermediate-risk RMS from ARST0531 (NCT00354835) trial. trial compared Vincristine, Dactinomycin, and Cyclophosphamide (VAC) to VAC...
ABSTRACT Background Multiparametric MRI (mpMRI) and fusion‐targeted biopsy (TB) have improved the detection of clinically significant prostate cancer (csPCa); however, it remains unclear whether secondary lesions (SLs) identified on mpMRI must also be biopsied in addition to index lesion (IL). Currently, American Urological Association European Urology guidelines suggest biopsying all lesions, but supporting data are sparse. This study examines including SL biopsies provides additional value...
Background Surgeons play a pivotal role in combating the opioid crisis that currently grips United States. Changing surgeon behavior is difficult, and degree to which behavioral science can steer surgeons toward decreased prescribing unclear. Methods This was single‐institution, single‐arm, pre‐ postintervention study examining of opioids by urologists for adult patients undergoing prostatectomy or nephrectomy. The primary outcome quantity prescribed oral morphine equivalents (OMEs) after...
In <i>α</i>-chloralose–anesthetized cats, we examined the role of GABA<sub>A</sub>, glycine, and opioid receptors in sacral neuromodulation-induced inhibition bladder overactivity elicited by intravesical infusion 0.5% acetic acid (AA). AA irritation significantly (<i>P</i> < 0.01) reduced capacity to 59.5 ± 4.8% saline control. S1 or S2 dorsal root stimulation at threshold intensity for inducing reflex twitching anal sphincter toe increased 105.3 9.0% 134.8 8.9% control, respectively....
No AccessJournal of UrologyPediatric Urology1 Aug 201624-Hour Urinary Parameters in Overweight and Obese Children with Urolithiasis Jathin Bandari, Pankaj P. Dangle, Timothy D. Lyon, Andy Lee, Francis X. Schneck, Glenn M. Cannon, Heidi A. Stephany, Michael C. Ost BandariJathin Bandari Department Urology, University Pittsburgh, Pennsylvania , DanglePankaj Dangle Division Children's Hospital LyonTimothy Lyon LeeAndy Lee Pittsburgh School Medicine, SchneckFrancis Schneck CannonGlenn Cannon...
Clinical trials serve as a critical source of information to guide evidence-based practices in urology. Conversely, that are abandoned consume significant resources and results underreported the literature.
Aims To investigate the effects of electrical stimulation sacral dorsal/ventral roots on irritation‐induced bladder overactivity, reveal possible different mechanisms under nociceptive conditions, and establish a large animal model neuromodulation. Methods Intravesical infusion 0.5% acetic acid (AA) was used to irritate induce overactivity in cats α ‐chloralose anesthesia. Electrical (5, 15, or 30 Hz) applied individual S1–S3 dorsal ventral at below motor threshold intensity. Repeated...
BACKGROUND Interactions between industry and prescribers have raised concerns regarding conflicts of interest. To the best authors' knowledge, quantitative data measuring these interactions been limited until recently. In current study, authors sought to determine whether an association exists payments prescriber behavior with regard abiraterone enzalutamide. METHODS Two Centers for Medicare Medicaid Services databases were combined analyze oncologists urologists who received and/or...
The influence of financial ties to pharmaceutical companies remains controversial. We aimed assess a potential relationship between payments and prescription patterns for degarelix denosumab.Medicare Provider Utilization Payment Data: Physician Other Supplier Public Use File (Medicare B) data containing 2012 claims compared OpenPayments (Sunshine Act) the second half 2013. Urologists medical oncologists who billed Medicare or denosumab were cross referenced in both databases aggregated into...
Under the Sunshine Act, pharmaceutical and product industry payments to physicians are reported in a public database. We sought characterize received by pediatricians first full year of disclosures 2014. used National Centers for Medicare Medicaid Services Open Payment files identify who payments. characteristics were stratified, descriptive statistical analysis was performed, including mean, median, ranges Between January 1, 2014, December 31, 35 697 amounting $30 031 960. General majority...