A5103255410- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- MRI in cancer diagnosis
- Pediatric Urology and Nephrology Studies
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Renal and related cancers
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Genetic and Kidney Cyst Diseases
- Testicular diseases and treatments
- Renal and Vascular Pathologies
- Prostate Cancer Diagnosis and Treatment
- Ureteral procedures and complications
- Bladder and Urothelial Cancer Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Infectious Disease Case Reports and Treatments
- Kidney Stones and Urolithiasis Treatments
- Organ Transplantation Techniques and Outcomes
- Prostate Cancer Treatment and Research
- Radiation Dose and Imaging
University of Pittsburgh Medical Center
2016-2025
Northwestern Memorial Hospital
2024
University of Pittsburgh
2015-2024
UPMC Health System
2024
University of Ottawa
2024
University Health Network
2023
University of Toronto
2023
The University of Texas Health Science Center at Houston
2023
Memorial Sloan Kettering Cancer Center
2023
UPMC Presbyterian
2007-2021
Obesity increases the risk of adverse outcomes during acute critical illnesses such as burns, severe trauma, and pancreatitis. Although individuals with more body fat higher serum cytokines lipase are likely to experience problems, roles that these characteristics play not clear. We used pancreatitis a representative disease investigate effects obesity on local organ function systemic processes. In obese humans, we found an increase in volume intrapancreatic adipocytes was associated...
“If you wish to converse with me,” said Voltaire, “define your terms.” How many a debate would have been deflated into paragraph if the disputants had dared define their terms! Will Durant: The Story of Philosophy
To assess the correlation between volumetric measurements of clot, semiquantitative clot burden indexes, and signs right heart dysfunction at computed tomographic (CT) pulmonary angiography in patients with acute embolism (PE) to determine whether are associated short-term mortality.This retrospective study was institutional review board approved HIPAA compliant. CT angiographic studies (January 2007 through December 2007) findings positive for PE were retrieved. Two readers evaluated...
Background & AimsIntraductal oncocytic papillary neoplasms (IOPNs) of the pancreas and bile duct contain epithelial cells with numerous, large mitochondria are cystic precursors to pancreatic ductal adenocarcinoma (PDAC) cholangiocarcinoma (CCA), respectively. However, IOPNs do not have genomic alterations found in other pancreatobiliary neoplasms. In fact, no recurrent been described IOPNs. PDACs without activating mutations KRAS gene rearrangements, so we investigated whether fusions...
Hepatocellular carcinoma (HCC) is one of the leading causes cancer-related death worldwide. The macroscopic growth pattern HCC subdivided into three categories: nodular, massive, and infiltrative. Infiltrative accounts for 7%-20% cases confirmed at pathologic analysis on basis spread minute tumor nodules throughout large regions liver. may represent a diagnostic challenge because it often difficult to distinguish from background changes in cirrhosis imaging. usually spreads over multiple...
OBJECTIVE. The aim of the present study was to compare diagnostic accuracy liver stiffness measurements (LSMs) obtained using MR elastography (MRE), transient (TE), and 2D shear wave (SWE) in patients with biopsy-proven nonalcoholic fatty disease (NAFLD). SUBJECTS AND METHODS. We prospectively enrolled 62 adult subjects (mean age [± SD], 50 ± 13 years; 58% women; body mass index [weight kilograms divided by square height meters], 35 7). Two-dimensional SWE, MRE, TE were performed at a mean...
To report the clinical profile and natural course in a large series of patients with hypertriglyceridemia (HTG) acute pancreatitis (AP).The history HTG-related is poorly defined.Medical records 121 serum triglycerides (TG) levels ≥500 mg/dL suffering 225 attacks AP between January 2001 to August 2013 treated at University Pittsburgh Medical Center were retrospectively studied. Structured data collected on initial presentation long-term outcomes (mean follow-up 64.7±42.8 mo). severity was...
Abstract Purpose To investigate the relevance of increasing b ‐values in evaluating liver fibrosis through agreement two diffusion‐weighted (DW) sequences. Materials and Methods A total 29 cirrhotic patients healthy volunteers were studied on a 1.5T system. Two single‐shot spin‐echo echo‐planar sequences acquired using sets ‐values: 0, 150, 250, 400 seconds/mm 2 (first sequence: DW1a) 400, 600, 800 (second DW2a). Apparent diffusion coefficients (ADCs) hepatic parenchyma calculated ADC maps....
The purposes of our study were to evaluate the surgical outcome cases radial scar without atypia diagnosed at imaging-guided percutaneous needle biopsy and determine whether mammographic sonographic features are able predict which lesions will be upgraded malignancy excision.The records 4,458 consecutive biopsies retrospectively reviewed. Surgical excision results available in 62 was highest-risk lesion stereotactically guided or sonographically biopsy. images findings underestimation rate...
The purpose of this study was to investigate whether breast MRI can be used rule out malignancy in patients with high-risk lesions diagnosed at imaging-guided core needle biopsy.The subjects were women consecutively registered between October 2004 and April 2010 who had mammographically or sonographically guided biopsy subsequently underwent surgical excision. MR images reviewed by two experienced radiologists. Lesions assessed as BI-RADS category 1-3 considered negative for malignancy, 4 5...
The Liver Imaging Reporting and Data System (LI-RADS) was created to standardize the diagnostic criteria for hepatocellular carcinoma (HCC) has undergone multiple revisions including a recent update in 2018 (v2018). primary aim of this study determine performance interrater reliability (IRR) LI-RADS v2018 distinguishing HCC from non-HCC hepatic malignancy patients 'at-risk' HCC. A secondary assess impact changes introduced algorithm.This retrospective combined 10-year experience...
Our aim was to compare retrospectively hepatic venous and delayed phase images for the detection of tumour washout during multiphasic multidetector row CT (MDCT) liver in patients with hepatocellular carcinoma (HCC).30 cirrhotic underwent MDCT 90 days before transplantation. performed contrast medium administration arterial phases, were obtained at 12, 55 120 s after trigger threshold. Two radiologists qualitatively evaluated lesion attenuation. Tumour subjectively objectively....