- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Neurosurgical Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Cardiovascular Health and Disease Prevention
- Vascular Malformations Diagnosis and Treatment
- Neurological Disorders and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Moyamoya disease diagnosis and treatment
- Cerebral Venous Sinus Thrombosis
- Neurological Complications and Syndromes
- Atrial Fibrillation Management and Outcomes
- Long-Term Effects of COVID-19
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma and Emergency Care Studies
- Renal and Vascular Pathologies
- Neurological Disease Mechanisms and Treatments
- Vascular Procedures and Complications
- Medical Imaging and Analysis
- Cerebrospinal fluid and hydrocephalus
University of Missouri
2018-2025
CentraCare Health System
2016-2025
University of Missouri Health System
2018-2025
Rehabilitation Institute of Kansas City
2019-2025
Cleveland Clinic
2009-2025
Columbia University
2007-2025
Cornell University
2004-2025
Yale University
2014-2025
Mount Sinai Hospital
2025
Icahn School of Medicine at Mount Sinai
2025
Background and Purpose— The authors present an overview of the current evidence management recommendations for evaluation treatment adults with acute ischemic stroke. intended audiences are prehospital care providers, physicians, allied health professionals, hospital administrators responsible stroke patients within first 48 hours from onset. These guidelines supersede prior 2007 2009 updates. Methods— Members writing committee were appointed by American Stroke Association Council’s...
Purpose— Our goal is to provide an overview of the current evidence about components evaluation and treatment adults with acute ischemic stroke. The intended audience physicians other emergency healthcare providers who treat patients within first 48 hours after In addition, information for policy makers included. Methods— Members panel were appointed by American Heart Association Stroke Council’s Scientific Statement Oversight Committee represented different areas expertise. reviewed...
Limited data are available to guide the choice of a target for systolic blood-pressure level when treating acute hypertensive response in patients with intracerebral hemorrhage.We randomly assigned eligible participants hemorrhage (volume, <60 cm(3)) and Glasgow Coma Scale (GCS) score 5 or more (on scale from 3 15, lower scores indicating worse condition) 110 139 mm Hg (intensive treatment) 140 179 (standard order test superiority intensive reduction blood pressure standard reduction;...
Purpose— Our goal is to provide an overview of the current evidence about components evaluation and treatment adults with acute ischemic stroke. The intended audience physicians other emergency healthcare providers who treat patients within first 48 hours after In addition, information for policy makers included. Methods— Members panel were appointed by American Heart Association Stroke Council’s Scientific Statement Oversight Committee represented different areas expertise. reviewed...
Data from trials investigating the effects and risks of endovascular thrombectomy for treatment stroke due to basilar-artery occlusion are limited.
Background and Purpose: Acute ischemic stroke may occur in patients with coronavirus disease 2019 (COVID-19), but risk factors, in-hospital events, outcomes are not well studied large cohorts. We identified comorbidities, COVID-19 or without acute compared stroke. Methods: analyzed the data from 54 health care facilities using Cerner deidentified dataset. The dataset included an emergency department inpatient encounter discharge diagnoses codes that could be associated to suspicion of...
On 11 March 2020, World Health Organization (WHO) declared the COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients with similar to those other respiratory tract infections. We present comprehensive set practice implications single document for clinicians caring adult acute confirmed or suspected infection.The were prepared after review data reach consensus among experts from 18 countries. writers used systematic literature reviews, reference previously...
Background: The authors compare the effectiveness and safety of endovascular treatment (EVT) versus best medical management (BMM) in strokes attributable to acute basilar artery occlusion (BAO). Methods: present analysis was based on ongoing, prospective, multicenter ATTENTION (Endovascular Treatment for Acute Basilar Artery Occlusion) trial registry China. Our analytic sample comprised 2134 patients recruited at 48 sites between 2017 2021 included 462 who received BMM 1672 EVT. We performed...
Abstract Objective To assess whether intra-arterial tenecteplase administered after successful endovascular recanalisation improves outcomes in patients with acute arterial occlusion of the posterior circulation. Design Multicentre randomised controlled trial. Setting 31 hospitals China, 24 January 2023 to August 2023. Participants 208 (grade 2b50-3 on extended thrombolysis cerebral infarction scale) an V4 segment vertebral artery; proximal, middle, or distal basilar P1 artery: 104 were...
Habitual sleep patterns may independently affect morbidity and mortality. However, the effect of habitual on risk for stroke coronary heart disease is unclear.We evaluated association between duration daytime somnolence (often or almost always taking naps) with incidence in a national cohort 7,844 adults who participated First National Health Nutrition Examination Survey Epidemiologic Follow-up Study. Cox proportional hazards analyses were used to examine these relationships during 10-year...
The Joint National Committee on High Blood Pressure identified a new category of blood pressure in adults termed prehypertension. Our objective was to determine the long-term risk cardiovascular diseases associated with this well-defined cohort adults.We evaluated association prehypertension (120 139/80 89 mm Hg) and hypertension (>140/90 incidence atherothrombotic brain infarction (ABI), all strokes, myocardial (MI), coronary artery disease (CAD) using pooled repeated measures Cox...
To determine the effect of continuous hypertonic (3%) saline/acetate infusion on intracranial pressure (ICP) and lateral displacement brain in patients with cerebral edema.Retrospective chart review.Neurocritical care unit a university hospital.Twenty-seven consecutive edema (30 episodes), including head trauma (n = 8), postoperative 5), nontraumatic hemorrhage infarction 6).Intravenous 3% to increase serum sodium concentrations 145 155 mmol/L.A reduction mean ICP within first 12 hrs...
Objective To evaluate the effect of intravenous bolus administration 23.4% saline (8008 mOsm/L) on refractory intracranial hypertension (RIH) in patients with diverse diseases. Design Retrospective chart review. Setting A neurosciences intensive care unit a university hospital. Patients We present eight and total 20 episodes increased pressure (ICP) resistant to standard modes therapy. Five had subarachnoid hemorrhage, one patient traumatic brain injury, tumor, another spontaneous basal...
Hemodynamic instability can occur acutely after carotid angioplasty and stent placement (CAS). We performed this study to determine the frequency of hemodynamic in a series patients who underwent CAS analyze factors associated with development postprocedural events.We reviewed medical records angiograms 51 (mean age 68.3+/-8.9 years) for symptomatic (n=29) or asymptomatic (n=22) artery stenosis. Any episodes hypotension (systolic blood pressure <90 mm Hg), hypertension >160 bradycardia...
Numerous case series have implicated cocaine use as a cause of both myocardial infarction (MI) and stroke on the basis temporal relationship between drug event onset. Increasing in US population, especially younger individuals, mandates more extensive investigation this relationship.We determined association with self-reported physician diagnosis MI or nationally representative sample 10 085 adults aged 18 to 45 years who participated Third National Health Nutrition Examination Survey. A...