Afshin Borhani‐Haghighi

ORCID: 0000-0002-4131-7990
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About
Contact & Profiles
Research Areas
  • Cerebral Venous Sinus Thrombosis
  • Acute Ischemic Stroke Management
  • Ocular Diseases and Behçet’s Syndrome
  • Cerebrovascular and Carotid Artery Diseases
  • Retinal and Optic Conditions
  • Venous Thromboembolism Diagnosis and Management
  • Long-Term Effects of COVID-19
  • Intracranial Aneurysms: Treatment and Complications
  • Neurological Disease Mechanisms and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Intracerebral and Subarachnoid Hemorrhage Research
  • COVID-19 Clinical Research Studies
  • Neurogenesis and neuroplasticity mechanisms
  • Pharmacological Effects and Toxicity Studies
  • Mesenchymal stem cell research
  • Migraine and Headache Studies
  • Multiple Sclerosis Research Studies
  • History of Medicine Studies
  • Stroke Rehabilitation and Recovery
  • Neurological Disorders and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Vasculitis and related conditions
  • Peripheral Neuropathies and Disorders
  • Neuroscience and Neuropharmacology Research
  • Epilepsy research and treatment

Shiraz University of Medical Sciences
2016-2025

John Hunter Hospital
2022-2023

Hunter Medical Research Institute
2022-2023

Faghihi Hospital
2005-2021

Namazi Hospital
2007-2014

Stem Cell Technology Research Center
2010-2013

Saint Louis University
2010-2012

Shiraz University
2006-2011

Neurology, Inc
2006-2011

Khalili Hospital
2009

On 11 March 2020, World Health Organization (WHO) declared the COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients with similar to those other respiratory tract infections. We present comprehensive set practice implications single document for clinicians caring adult acute confirmed or suspected infection.The were prepared after review data reach consensus among experts from 18 countries. writers used systematic literature reviews, reference previously...

10.1177/1747493020923234 article EN other-oa International Journal of Stroke 2020-05-03

The purpose of this study was to evaluate the mortality rates associated with cerebral venous-sinus thrombosis in a large national sample.A cohort patients identified from National Inpatient Sample database for years 2000 2007. According International Classification Diseases, 9th Revision, Clinical Modification codes, is categorized into pyogenic and nonpyogenic groups. Multivariate logistic regression analysis used assess covariates hospital mortality.Among 3488 patients, overall rate...

10.1161/strokeaha.111.635664 article EN Stroke 2011-10-14

SARS-CoV-2 induced coagulopathy can lead to thrombotic complications such as stroke. Cerebral venous sinus thrombosis (CVST) is a less common type of stroke which might be triggered by COVID-19. We present series CVST cases with infection.

10.1016/j.jns.2020.117183 article EN other-oa Journal of the Neurological Sciences 2020-10-14

Recent studies suggest that cholinergic dysfunction does not provide a complete account of age-related cognitive deficits, and other neuronal systems like monoaminergic hypofunction are involved. In several studies, selective serotonin reuptake inhibitors demonstrated promotion in neurogenesis the hippocampus enhanced memory cognition. The aim this study is to survey effect augmentation on cognition activities daily living patients with Alzheimer's disease.The trial was designed as 12-week...

10.1097/jcp.0b013e31814b98c1 article EN Journal of Clinical Psychopharmacology 2007-09-12

Neurophysiological and computer modelling studies have shown that electrode montage is a critical parameter to determine the neuromodulatory effects of transcranial direct current stimulation (tDCS). We tested these results clinically by systematically investigating optimal tDCS in stroke. Ten patients received counterbalanced randomised order following conditions (i) anodal affected M1 (primary motor cortex) cathodal unaffected ('bilateral tDCS'); (ii) contralateral supraorbital area...

10.3109/09638288.2010.532283 article EN Disability and Rehabilitation 2010-11-26

To investigate the efficacy and safety of cutaneous application menthol 10% solution for abortive treatment migraine.Peppermint its active ingredient have long been used various pain conditions including headache.This is a randomised, triple-blind, placebo-controlled, crossed-over study conducted in neurology Clinic Nemazee Hospital, affiliated with Shiraz University Medical Sciences, Shiraz, southern Iran, from March 2007 to 2008. The patients were recruited via local newspaper...

10.1111/j.1742-1241.2009.02215.x article EN International Journal of Clinical Practice 2010-02-05

Abstract Introduction Cell‐based therapy is considered as promising strategy to cure stroke. However, employing appropriate type of stem cell fulfill many therapeutic needs cerebral ischemia still challenging. In this regard, the current study was designed elucidate potential epidermal neural crest cells (EPI‐NCSCs) compared bone marrow mesenchymal (BM‐MSCs) in rat model ischemic Methods Ischemic stroke induced by middle artery occlusion (MCAO) for 45 minutes. Immediately after reperfusion,...

10.1111/cns.13370 article EN cc-by CNS Neuroscience & Therapeutics 2020-04-12

The abnormal processing of amyloid-β peptide (Aβ) and resultant formation fibrillar Aβ (fAβ) are major events in the pathogenesis Alzheimer disease (AD). Microglia as phagocytic cells brain can engulf digest fAβ within their acidic lysosomes. lysosomes AD patients less therefore capable clearance fAβ. Vacuolar proton pumps (V-ATPases) which found abundantly microglia macrophages, acidify by pumping protons into these structures. Proton pump inhibitors (PPIs) inhibit V-ATPases These drugs...

10.1111/j.1365-2710.2009.01100.x article EN Journal of Clinical Pharmacy and Therapeutics 2009-09-10
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