- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Telemedicine and Telehealth Implementation
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Cardiovascular Health and Disease Prevention
- Neurological Disorders and Treatments
- Neurosurgical Procedures and Complications
- Retinal and Optic Conditions
- Meta-analysis and systematic reviews
- Dementia and Cognitive Impairment Research
- Cardiovascular and Diving-Related Complications
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- Migraine and Headache Studies
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
- Patient Satisfaction in Healthcare
- Mobile Health and mHealth Applications
- Clinical practice guidelines implementation
- Health Sciences Research and Education
Mayo Clinic in Arizona
2016-2025
Mayo Clinic in Florida
2015-2025
WinnMed
2015-2025
Neurology, Inc
2012-2025
Mayo Clinic
2011-2024
Digital Health Cooperative Research Centre
2024
Jacksonville College
2009-2023
Health and Education Research Management and Epidemiologic Services (United States)
2023
Mayo Clinic Hospital
2013-2022
Loyola University Chicago
2010-2020
Background and Purpose— The authors present an overview of the current evidence management recommendations for evaluation treatment adults with acute ischemic stroke. intended audiences are prehospital care providers, physicians, allied health professionals, hospital administrators responsible stroke patients within first 48 hours from onset. These guidelines supersede prior 2007 2009 updates. Methods— Members writing committee were appointed by American Stroke Association Council’s...
Endovascular therapy is increasingly used after the administration of intravenous tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic stroke, but whether a combined approach more effective than t-PA alone uncertain.
Rationale Trials conducted decades ago demonstrated that carotid endarterectomy by skilled surgeons reduced stroke risk in asymptomatic patients. Developments stenting and improvements medical prevention of caused atherothrombotic disease challenge understanding the benefits revascularization. Aim Carotid Revascularization Medical Management for Asymptomatic Stenosis Trial (CREST-2) will test whether or plus contemporary intensive therapy is superior to alone primary patients with high-grade...
The recent "Advanced Neuroimaging for Acute Stroke Treatment" meeting on September 7 and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, emergency physicians, neuroimaging research scientists, members of the National Institute Neurological Disorders (NINDS), Biomedical Imaging Bioengineering (NIBIB), industry representatives, US Food Drug Administration (FDA) to discuss role advanced acute treatment. goals were assess state-of-the-art practice terms imaging...
The present study of current telemedicine users is a unique attempt to understand the barriers and motivational factors related utilization telemedicine.A survey emergency critical care remote presence was conducted determine that motivate impede acceptance maintenance robotic (RTM) program.The majority were in Emergency Department or Intensive Care Unit.E-mail invitations sent 483 individuals representing 63 healthcare institutions groups North America Europe. Respondents directed Web-based...
To conduct a cost-effectiveness analysis of telestroke--a 2-way, audiovisual technology that links stroke specialists to remote emergency department physicians and their patients--compared usual care (i.e., departments without telestroke consultation or experts).A decision-analytic model was developed for both 90-day lifetime horizons. Model inputs were taken from published literature where available supplemented with western states' experiences. Costs gathered using societal perspective...
Background— A hub-and-spoke telestroke network is an effective way to extend quality acute stroke care remote hospitals and improve patient outcomes. This study assessed the cost-effectiveness of a in management ischemic from perspectives network, hub hospital, spoke hospital. Methods Results— model was developed compare costs effectiveness with without over 5-year time horizon. The considered differences rates teleconsultations, intravenous thrombolysis, endovascular therapies, spoke-to-hub...
Telemedicine can disseminate vascular neurology expertise and optimize recombinant tissue plasminogen activator (rt-PA) use for acute ischemic stroke in rural underserved communities. The purpose of this study was to prospectively assess whether telemedicine or telephone superior decision-making.
The following telestroke guidelines were developed to assist practitioners in providing assessment, diagnosis, management, and/or remote consultative support patients exhibiting symptoms and signs consistent with an acute stroke syndrome, using telemedicine communication technologies. Although practices may include the more broad utilization of across entire continuum care, some even consulting on all neurologic emergencies, this document focuses phase stroke, including both pre- in-hospital...
Telemedicine techniques can be used to address the rural-metropolitan disparity in acute stroke care. The Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) trial reported more accurate decision making for telemedicine consultations compared with telephone-only and that California-based research network facilitated high rate of thrombolysis use, improved data collection, low risk complications, technical favorable assessment times. main objective STRokE DOC Arizona...
Epidemiological studies have found strong correlations between elevated plasma fibrinogen levels and both ischemic stroke incidence mortality. Little is known about the influence of on functional outcome.Placebo data from Stroke Treatment with Ancrod Trial (STAT) European (ESTAT) were analyzed. Fibrinogen determined within 3 hours or 6 onset at preset intervals throughout 5 days intravenous infusions. Barthel Index scores 90 quantified outcomes. The association initial outcomes was evaluated...
Background and Purpose— Telestroke reduces acute stroke care disparities between urban centers rural hospitals. Current technologies used to conduct remote patient assessments have high start-up costs, yet they cannot consistently establish quality timely connections. Smartphones can be for high-quality video teleconferencing. They are inexpensive ubiquitous among health providers. We aimed study the reliability of teleconferencing using smartphones conducting National Institutes Health...
Previous studies of multiple-day dosing with the defibrinogenating agent, ancrod, in acute ischemic stroke yielded conflicting results but suggested that a brief regimen might improve efficacy and safety. The Ancrod Stroke Program was designed to test this concept subjects beginning ancrod or placebo within 6 hours onset stroke.Five hundred who could begin receiving study material symptom were infused intravenously either (0.167 IU/kg per hour) over 2 3 hours. primary outcome dichotomized,...
Background and Purpose— Detection of an intracardiac shunt is frequently sought during the evaluation patients with cryptogenic ischemic stroke agitated saline intravenous injection, or “bubble study” (BS), performed in most cases. We present first attempt to identify clinical features who had cerebral events BS. Methods— Using a list serve established by American Academy Neurology, member posted question regarding safety BS patent foramen ovale. A standardized questionnaire was used gather...