A5048245328- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiac tumors and thrombi
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac Arrhythmias and Treatments
- Congenital Heart Disease Studies
- Pericarditis and Cardiac Tamponade
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Pectus Deformity Diagnosis and Treatment
- Takotsubo Cardiomyopathy and Associated Phenomena
- Aortic Thrombus and Embolism
- Pulmonary Hypertension Research and Treatments
- Trauma Management and Diagnosis
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Cardiovascular Syncope and Autonomic Disorders
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- Non-Invasive Vital Sign Monitoring
- Automotive and Human Injury Biomechanics
- Cardiovascular Disease and Adiposity
Mayo Clinic in Arizona
2014-2025
Mayo Clinic Hospital
2009-2024
Texas Tech University
2024
Texas Tech University Health Sciences Center
2024
Mayo Clinic in Florida
2002-2023
Kentucky Educational Television
2023
WinnMed
2022
Mayo Clinic
1997-2013
Boston University
2009
Harvard University
2009
Background— Left ventricular dysfunction is an indication for aortic valve replacement (AVR) in patients with severe regurgitation (AR). However, the postoperative outcome of AR and a markedly low ejection fraction (EF) not known. Methods Results— The study group consisted total 450 who had AVR isolated between 1980 1995. Patients reduced left function (EF <35%, LoEF, n=43) were compared those moderate reduction 35% to 50%, MedEF, n=134) normal ≥50%, Nl EF, n=273). operative mortality...
Four hundred eighty-four patients undergoing mammography and 498 visiting their obstetrician-gynecologist were asked whether they would take a breast cancer 1 (BRCA1) test to detect genetic susceptibility cancer. More than 90% in both groups said the test. Women more likely accept if regularly having examinations by physician, believed that effectively detects early cancer, is curable. If shown have inherited susceptibility, many reported be very anxious, want repeated, examine breasts often...
To compare and contrast 3 different echocardiographic methods used to measure left atrial (LA) volume: biplane area length (AL), modified Simpson (SIMP), prolate ellipse (PE) methods. A review of consecutive patients who presented our outpatient echocardiography laboratory for a resting transthoracic study between April 2006 May was performed. Echocardiograms were reexamined LA volume measured using the AL, SIMP, PE Of 102 evaluated, 97 had all significant difference in measurement mean ± SD...
Background and Aims: Atrial fibrillation (AF) may be a risk factor for severe functional tricuspid valve regurgitation (FTR). We aimed to determine the predictors of FTR in patients with AF. Methods Results: From our echocardiographic laboratory database, we searched reviewed medical records consecutive AF seen at Mayo Clinic Arizona from 2002 through 2009. Our search identified 42 who met all inclusion criteria. These (cases) were compared 38 (controls) had no greater than mild...
Background and Purpose— Detection of an intracardiac shunt is frequently sought during the evaluation patients with cryptogenic ischemic stroke agitated saline intravenous injection, or “bubble study” (BS), performed in most cases. We present first attempt to identify clinical features who had cerebral events BS. Methods— Using a list serve established by American Academy Neurology, member posted question regarding safety BS patent foramen ovale. A standardized questionnaire was used gather...
Background: The assessment of the severity aortic valve stenosis is done by either invasive catheterization or non-invasive Doppler Echocardiography in conjunction with simplified Bernoulli equation. catheter measurement generally considered more accurate, but procedure also likely to have dangerous complications. Objective: focus here on examining computational fluid dynamics as an alternative method for analyzing echo data and determining whether it can provide results similar measurement....
Objective To determine the association between serum vitamin D level and left ventricular (LV) diastolic dysfunction. Background Vitamin deficiency has been shown in observational prospective studies to be associated with cardiovascular diseases including coronary artery disease, LV hypertrophy systolic heart failure. Even though dysfunction is an early manifestation of cardiac there no study that examines whether a Method A retrospective review 1011 patients (679 women) was conducted...
Background/Objectives: The peak oxygen consumption (VO2) during cardiopulmonary exercise testing (CPET) is a strong predictor of all-cause mortality. cardiac output, key determinant VO2, can be assessed using resting echocardiographic parameters. heart rate recovery and ventilatory efficiency (VE/VCO2 slope) from CPET offer additional insights into cardiovascular fitness. Methods: This study aimed to identify parameters that predict the percentage predicted recovery, VE/VCO2 slope in general...
Anomalous insertion of the papillary muscle (PM)/chordae tendineae is a rare but important cause dynamic left ventricular outflow tract (LVOT) obstruction in patients with hypertrophic cardiomyopathy or cardiac amyloidosis. These anomalies are often challenging to diagnose 2-D Echo, yet accurate diagnosis critical determining whether proceed an extended septal myectomy instead standard for relief. We report two cases anomalous PM causing LVOT facilitated by real-time 3-D echocardiograms.
Pectus excavatum exists as varying anatomic deformities and compression of the right heart by chest wall can lead to patient symptoms including dyspnea pain with exertion. Echocardiography be difficult but is critical evaluation diagnosis this population. Modifying standard views such biplane transthoracic 3-D transesophageal may necessary in some patients due limitations from abnormal anatomy deformed anterior wall. Apical four-chamber when seen clearly usually visualize any extrinsic...
Abstract Because pulmonary venous pressure has never been measured, it is unclear whether wedge measures left atrial pressure, as commonly assumed, or more upstream in the capillary beds. Fluid‐filled mean artery and were compared with obtained high‐fidelity micromanometer catheters eight lightly sedated dogs over a physiologic range of filling pressures. In all conditions, was virtually identical (r = 0.99) to (slope 0.99; intercept −0.46 mm Hg). At same time, (17.1 ± 6.5 Hg) intermediate...
Background: Cellular transplantation has emerged as promising approach for treating cardiac diseases. However, a poor engraftment rate limits our understanding on how transplanted cardiomyocytes contribute to function in the recipient’s heart. Methods: The CRISPR/Cas9 technique was employed stable and constitutive gene expression human-induced pluripotent stem-cell-derived (hiPSC-CMs). Myocardial infarction induced adult immunodeficient mice, followed by intramyocardial injection of...
We studied left ventricular flow patterns for a range of rotational orientations bileaflet mechanical heart valve (MHV) implanted in the mitral position an elastic model beating ventricle (LV). The was rotated through 3 angular positions (0, 45, and 90 degrees) about LV long axis. Ultrasound scans were obtained four apical 2-dimensional (2D) imaging projections, each with 45 degrees separation. Particle velocimetry performed during diastolic period to quantify in-plane velocity field by...