To determine the serum thiol/disulphide homeostasis in preeclampsia and to investigate association with clinical parameters.Forty-three pregnant women 43 healthy, uncomplicated pregnancies were included study. Native thiol, disulphide, total thiol concentrations measured by a novel automated method.The native levels significantly lower when compared healthy group (p < 0.001). There significant correlations among homeostatic parameters preeclampsia.Serum may have role pathogenesis can be...

To assess thiol/disulphide homeostasis and lipid accumulation product index, to determine whether they are associated with increased cardiovascular disease (CVD) risk or not in overweight adolescents polycystic ovary syndrome (PCOS).Case-control study.Education Research Hospital.Group 1: 43 overweight+PCOS, Group 2: 45 normal weight+PCOS, 3: 27 4: 96 age-matched, weight healthy controls.Serum profiles, hormonal parameters were measured. Lipid index (LAP index) model assessment (HOMA-IR)...

Abstract Our aim was to investigate whether any hematological changes readily detectable by simple complete blood count (CBC), as well fasting and postprandial total serum bile acid (SBA) levels, have diagnostic values for the prediction of adverse pregnancy outcomes in intrahepatic cholestasis (ICP). A prospective, case control study carried out including 217 pregnant women (117 with ICP 100 healthy controls). The main outcome measures investigated were preterm delivery, APGAR scores,...

Objective: The main aim of this study was to investigate thiol/disulfide homeostasis at 24–28 weeks pregnancy and evaluate whether it is predictive for adverse perinatal outcomes or not in gestational diabetes mellitus (GDM).Methods: A total 110 pregnant women (74 GDM patients 36 age- BMI-matched healthy women) were enrolled prospective case–control study. Thiol/disulfide evaluated with a novel spectrophotometric method determine if there an association GDM, by using logistic regression...

Placenta previa (PP) is a potential life-threatening pregnancy complication. Pro-brain natriuretic peptide (ProBNP), creatine kinase (CK), cardiac form of CK (CK-MB) and Troponin I are circulatory biomarkers related to functions. We aimed determine whether these PP placenta accreta.In this case-control study, fifty-four pregnant women who attended our tertiary care center for perinatology with the diagnosis totalis, them, 14 patients accreta were recruited as study groups. Forty-six...

Abstract Morbidly adherent placenta (MAP) is a growing concern currently and still diagnostic challenge for obstetricians. As emergency hysterectomy due to unscheduled delivery in MAP carries significant risks, we aimed evaluate whether first second trimester serum analytes may be used the prediction of requiring hysterectomy. A retrospective chart review all identified cases previa totalis with without was performed. total 316 pregnant women diagnosed as were included analysis. Cases...

Fetal lymphangioma is a hamartomatous congenital anomaly of the lymphatic system, which embracing fetal skin (sometimes mucous membranes) and subcutaneous tissue. The general consensus that it occurs as result failure in drainage. A 36-year-old pregnant woman was referred to our perinatology clinic at 22 weeks' gestation, because right-sided axillary mass revealed by ultrasonography. measuring 5x7x7cm three dimensions had multilocular structure without colour Doppler flow well-circumscribed...

Our aim was to investigate serum clusterin levels in preeclampsia and determine whether any changes are useful distinguishing the presence of concomitant intrauterine growth restriction (IUGR) predicting adverse pregnancy outcomes.A prospective case-control study carried out which included 86 pregnant women (47 patients with 39 healthy controls). Maternal samples obtained from all participants were determined by enzyme-linked immunosorbent assay (ELISA).Compared controls, had significantly...

The main aim of this study was to investigate the first trimester maternal serum secreted frizzle-related protein-5 (Sfrp-5) levels and evaluate predictive value on subsequently developed gestational diabetes mellitus (GDM).A total 40 pregnant women who GDM 44 age- pre-pregnancy BMI-matched healthy were enrolled in prospective case-control study. First Sfrp-5 evaluated determine if there is an association with onset GDM, by using logistic regression analysis.Decreased (OR = 14.332, 95%CI:...

Background/aim: The main aim of this study was to investigate serum total oxidant status (TOS), antioxidant (TAS), oxidative stress index (OSI), and arylesterase levels in pregnant women with placenta accreta compare those age-matched healthy women. Materials methods: A 27 who had clinically pathologically proven 30 age- BMI- matched were enrolled case control study. Maternal TOS, TAS, OSI, evaluated using logistic regression analysis determine if there an association abnormal placental...

Abstract Aim: The aim of this study was to investigate the serum oxidative stress markers, antioxidant enzyme and tumor necrosis factor-α (TNF-α) levels at 24–28 weeks gestation evaluate predictive value them on subsequent treatment protocol in gestational diabetes mellitus (GDM). Methods: A total 58 GDM patients (30 treated with only conventional healthy dietary recommendation (CHDR), 28 insulin) 30 pregnant women gestation, were enrolled prospective case-control study. status, TNF-α...

ADAMTS-1 is a matrix metalloproteinase which cleaves versican in the cumulus oocyte complex under effect of luteinizing hormone surge periovulatory period. Altered levels may have role pathogenesis polycystic ovary syndrome (PCOS). We aimed to determine serum and (a disintegrin with thrombospondin motif-1) PCOS patients compare results healthy controls.Thirty-eight forty controls aged between 15 22 years were included study. They sampled according their basal hormone, versican, levels. Serum...

Our aim in this study was to investigate the effect of maternal obesity and gestational diabetes mellitus (GDM) on cord blood dynamic thiol/disulfide homeostasis.A prospective case-control carried out 125 pregnant women (27 GDM, 30 obese, 68 controls). Cord samples were collected from all participants native thiol-disulfide exchanges examined with automated method enabling measurement both sides balance.Disulfide amounts, disulfide/native thiol disulfide/total ratios increased (p < 0.001),...

Women with polycystic ovary syndrome (PCOS) have an increased cardiometabolic risk. Similarly, it was previously shown that atherosclerotic and cardiovascular risk is in the general population lower serum Klotho levels. The aim of this study to investigate lotho thiol/disulfide levels women non-obese PCOS compared healthy controls also relationship homeostasis factors.In prospective case control study, human alpha aged between 19-33 were their age BMI matched non - controls. In addition,...

Despite medical advances, rising awareness, and satisfactory care facilities, placenta previa (PP) remains a challenging clinical entity due to the risk of excessive obstetric hemorrhage. Etiological concerns gave way life-saving about prediction maternal outcomes Our study aimed detect an early predictive marker previa.Ninety-three pregnant patients diagnosed with PP 247 controls were recruited for this retro-spective study. Platelet leukocyte indices compared between two groups.The groups...

Objectives: The aim of the study was to determine maternal serum total antioxidant status (TAS), oxidant (TOS), oxidative stress index (OSI), paraoxonase (PON) and arylesterase levels in severe preeclamptic pregnants also investigate whether these parameters are implicated occurence perinatal morbidity or not. Material methods: A case-control carried out including 60 pregnant women (30 with preeclampsia 30 healthy controls). optimal cut off points markers for diagnosis prediction adverse...

The aim of the present study is to compare pregnancy outcomes among patients with and without thyroid antibodies and/or subclinical hypothyroidism investigate whether there an association between first trimester maternal plasma interleukin-6 (IL-6) levels adverse outcomes.A case-control was carried out including 83 pregnant women (40 antibody positive 43 healthy controls). predictive value IL-6 on were investigated. optimal cut-off points for determining fetal evaluated by receiver operating...