- Circadian rhythm and melatonin
- Light effects on plants
- Photoreceptor and optogenetics research
- Advanced Memory and Neural Computing
- Electron Spin Resonance Studies
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Neuroscience and Neural Engineering
- X-ray Diffraction in Crystallography
- Cellular Mechanics and Interactions
- Phase-change materials and chalcogenides
- Nonlinear Optical Materials Studies
- Advanced Battery Materials and Technologies
- Advanced battery technologies research
- Gene expression and cancer classification
- Carbohydrate Chemistry and Synthesis
- Stress Responses and Cortisol
- Health, psychology, and well-being
- Microfluidic and Bio-sensing Technologies
- Metal-Catalyzed Oxygenation Mechanisms
- Bioinformatics and Genomic Networks
- Advancements in Battery Materials
- Photochromic and Fluorescence Chemistry
- Orbital Angular Momentum in Optics
- Tryptophan and brain disorders
University of California, Davis
2017-2024
University of California System
2017
Chinese University of Hong Kong
2006-2013
California Institute of Technology
2006-2008
The peroxide dianion reacts with CO<sub>2</sub> in polar aprotic organic media to afford the hydroperoxycarbonate and carbonate radical anions. These highly reactive species, if formed lithium–O<sub>2</sub> cells, can lead cell degradation <italic>via</italic> oxidation of electrolyte electrode.
Abstract Circadian clocks respond to temperature changes over the calendar year, allowing organisms adjust their daily biological rhythms optimize health and fitness. In Drosophila , seasonal adaptations compensation are regulated by temperature-sensitive alternative splicing (AS) of period ( per ) timeless tim genes that encode key transcriptional repressors clock gene expression. Although clk encodes critical activator expression, AS its transcripts potential role in regulation function...
As the only circadian oscillator that can be reconstituted in vitro with its constituent proteins KaiA, KaiB, and KaiC using ATP as an energy source, cyanobacterial serves a model system for detailed mechanistic studies of day–night transitions clocks general. The day-to-night transition occurs when KaiB forms night-time complex to sequester latter which interacts during day promote autophosphorylation. However, how remains poorly understood, despite available structures bound hexameric...
The use of an optical tweezer for moving dissociated neurons was studied. main features the tweezers are outlined as well general principles its operation. Infrared beams at 980 and 1064 nm were used, focused so to make a trap holding them. Absorption by cells those wavelengths is very small. Experiments done evaluate nonsticky substrate coatings, from which could be easily lifted with tweezers. maximum speed cell movement function laser power determined. Detailed studies damage beam...
The cyanobacterial circadian clock in Synechococcus elongatus consists of three proteins, KaiA, KaiB, and KaiC. KaiA KaiB rhythmically interact with KaiC to generate stable oscillations phosphorylation a period 24 h. observation when the proteins are reconstituted combined vitro makes it an ideal system for understanding its underlying molecular mechanisms clocks general. These were historically monitored by gel electrophoresis reaction mixtures based on differing electrophoretic mobilities...
A homologous series of oligo(amide-triazole)s (OAT) [OAT-CO2H-2 n and OAT-COPrg-(2 n+1)] with an increasing number primary amide (CONH) triazole hydrogen-bonding functionalities was prepared by iterative synthetic procedure. It found that their self-assembly thermoreversible gelation strength had a strong correlation to the moieties in oligomers. There also existed threshold value CONH units, above which all oligomers became organogelators. Hence, ≤4 units are devoid intermolecular hydrogen...
We present a refined method and design for building parylene neurocages in vitro studies of live neural networks. Parylene are biocompatible very robust, making them ideally suited studying the synaptic connections between individual neurons to gain insight into learning memory. The neurocage fabrication process incorporates electrodes allow stimulation recording action potentials. These can be fabricated on either silicon or glass substrates. resulting have long term cell survival rate...
Development and preliminary characterization on the performance of a micro-bubble generator using carbon nanotubes (CNTs) as heating elements are presented. Dielectrophoretic force was used to align CNTs between fabricated micro-electrodes. The contacts electrodes were fixed by patterned SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> thin film. Localized high temperature due Joule-heating generated an AC current few hundred muA (in...
Background: Psychoneuroimmunology is the study of interactive relationships between mind and immune system. This article looks at psychological factors influencing infection susceptibility. A thorough review research evidence on this topic beyond scope article. Recent infection-specific psychoneuroimmunology literature therefore highlighted possible underlying mechanisms are summarized. Content: Current shows that susceptibility to infections allergies can be increased by chronic stress...
Circadian clocks respond to temperature changes over the calendar year, allowing organisms adjust their daily biological rhythms optimize health and fitness. In Drosophila , seasonal adaptations are regulated by temperature-sensitive alternative splicing (AS) of period ( per ) timeless tim genes that encode key transcriptional repressors clock gene expression. Although Clock Clk encodes critical activator circadian expression, AS its transcripts potential role in regulation function have not...
We present a refined method and design for building parylene neurocages in vitro studies of live neural networks. Parylene are biocompatible very robust, making them ideally suited studying the synaptic connections between individual neurons to gain insight into learning memory. The neurocage fabrication process incorporates electrodes allow stimulation recording action potentials. These can be fabricated on either silicon or glass substrates. resulting have long term cell survival rate...
A newly developed device using organic dye-polymer systems (DPS) has been shown to be remarkable photosensitive media for volumetric data storage. Based on two-photon absorption, could 'bit-by-bit' written in and florescent 'page-by-page' read out both by single beams at different wavelengths. Key technologies industrial application are discussed.