A5058875026- Hydrology and Watershed Management Studies
- Immunotherapy and Immune Responses
- Hydrology and Sediment Transport Processes
- Cryospheric studies and observations
- Marine and coastal ecosystems
- Dermatology and Skin Diseases
- Climate variability and models
- Atmospheric and Environmental Gas Dynamics
- Psoriasis: Treatment and Pathogenesis
- Methane Hydrates and Related Phenomena
- RNA Interference and Gene Delivery
- Remote Sensing in Agriculture
- Rheumatoid Arthritis Research and Therapies
- Soil Geostatistics and Mapping
- Regional Development and Environment
- Fish Ecology and Management Studies
- Aquatic Ecosystems and Phytoplankton Dynamics
- Wound Healing and Treatments
- Geological and Geophysical Studies
- Soil erosion and sediment transport
- Computer Graphics and Visualization Techniques
- Climate change and permafrost
- Advanced Polymer Synthesis and Characterization
- interferon and immune responses
- Ecology and Vegetation Dynamics Studies
Swedish University of Agricultural Sciences
2024-2025
Peking University
2023-2024
Lund University
2018-2024
Sun Yat-sen University
2020-2022
Cell-free DNA (cfDNA) released from damaged or dead cells combines with LL37 and is converted into an immune response activator to exacerbate psoriasis. Here, we show that cationic nanoparticles (cNPs) efficiently compete for the DNA-LL37 immunocomplex inhibit DNA-LL37-induced cell activation. Using phenotypical images, psoriasis area severity index scoring, histology, immunohistochemical analysis, demonstrate topical application of cNPs on psoriasiform skin a mouse model relieves psoriatic...
Extended growing season lengths under climatic warming suggest increased time for plant growth. However, research has focused on impacts to the timing or duration of distinct phenological events. Comparatively little is known about relative allocation events, example, proportion dedicated leaf growth versus senescence. We use multiple satellite and ground-based observations show that, despite recent climate change during 2001 2020, ratio allocated vegetation green-up over senescence remained...
Abstract East Asia (China, Japan, Koreas, and Mongolia) has been the world's economic engine over at least past two decades, exhibiting a rapid increase in fossil fuel emissions of greenhouse gases (GHGs) expressed recent ambition to achieve climate neutrality by mid‐century. However, GHG balance its terrestrial ecosystems remains poorly constrained. Here, we present synthesis three most important long‐lived (CO 2 , CH 4 N O) budgets during decades 2000s 2010s, following dual constraint...
River transport of dissolved organic carbon (DOC) to the ocean is a crucial but poorly quantified regional cycle component. Large uncertainties remaining on riverine DOC export from China, as well its trend and drivers change, have challenged reconciliation between atmosphere-based land-based estimates China's land sink. Here, we harmonized large database in-situ measurements applied random forest model, quantify fluxes (FDOC ) concentrations (CDOC in rivers across China. This study proposes...
Rivers play a critical role in the global carbon cycle, transporting from land to ocean while emitting significant amounts of CO2 atmosphere. Yet, processes controlling partitioning fluvial inorganic (IC) between atmospheric release and downstream transport remain poorly understood due complex hydrodynamic biogeochemical interactions.Building on Budyko’s hydrological framework, we propose dimensionless approach uncover primary controls IC partitioning. Two key parameters are...
Dissolved inorganic carbon (DIC) transport along the land-ocean continuum, accounts for ~50% of lateral fluxes at global scale. One major source riverine DIC comes from atmospheric dioxide (CO2) uptake by chemical weathering process, which has currently been recognized as a potentially significant contributor climate mitigation in addition to photosynthesis. However, we still have no clue how much this sink would end up regional scale and how/whether export changed over space time. China...
Chronic inflammation is a typical feature and major impediment in refractory diabetic foot ulcer (DFU). High levels of extracellular cell-free nucleic acid (cfDNA) have recently been known to play critical role the cause inflammation. Herein, we fabricated polyacrylamide-based cationic hydrogels topically applied them rat model. The cfDNA level wound area was significantly reduced after hydrogel adsorption, eliminated. In turn, closure promoted without introducing systemic toxicity. Cationic...
A central paradigm in nanomedicine is that when synthetic nanoparticles (NPs) enter the body, they are immediately cloaked by a corona of macromolecules (mostly proteins) mediates role physico-chemical properties NP biological functions (the "coronation paradigm"). In this work, we focused on assessment paradigm" for cationic NPs (cNPs) used as rheumatoid arthritis (RA) drugs due to their ability scavenge cell-free DNA (cfDNA). We fabricated series cNPs uniformly coated with single or...
Abstract Climate change has the potential to alter hydrological regimes and expand saturated areas in permafrost environments, which are important sources of organic carbon. The sources, transfer zones, delivery mechanisms carbon into stream network controlled by morphometric properties catchment; however, utility limitations these as predictors dissolved concentrations have rarely been systematically evaluated. This study tested relationships between 18 indicators observed (DOC) Stordalen...
Abstract Lake surface water temperature (LSWT) is a key parameter in lake energy budget and highly vulnerable to climate change. However, the long‐term trends LSWT across China their driving factors remain uncertain. Here, we used calibrated model simulate over 1979–2018 for 91 large lakes (>100 km 2 ) China. Simulations reveal an overall warming trend (0.040°C yr −1 , p < 0.05), but with spatial variations. The majority of these show significant (84%, 0.053°C ), while cooling found...
Abstract Terracing is an important measure to conserve water and soil on the Loess Plateau. Previous studies have showed that due extreme rainstorms a lack of maintenance, loess terraces experienced degradation predominantly as collapses sinkholes. Investigating hydrological processes associated with terrace vital understand mechanisms maintain terraced landscape sustainability. Using high‐resolution digital elevation model (DEM) based unmanned aerial vehicle (UAV)remote sensing, well...
Abstract Drainage networks are the basis for segmentation of watersheds, an essential component in hydrological modelling, biogeochemical applications, and resource management plans. With rapidly increasing availability topographic information as digital elevation models (DEMs), there have been many studies on DEM‐based drainage network extraction algorithms. Most traditional methods require preprocessing DEM order to remove “spurious” sink, which can cause unrealistic results due removal...
Abstract Rivers are pivotal in the global carbon cycle, transporting terrestrial to ocean while emitting significant amount of atmosphere. However, partitioning fluvial inorganic (IC) between downstream transport and atmospheric evasion remains uncertain due intricate hydrodynamic biogeochemical processes. Inspired by Budyko's hydrological work, this study introduces a dimensionless framework identify critical factors IC partitioning: fraction equilibrium with atmosphere ratio advection...
Abstract Drainage networks delineated from Digital Elevation Models (DEMs), are the basis for modelling of geomorphological and hydrological processes, biogeochemical cycling, water resources management. Besides providing effective models flows, automatically extracted drainage based on topography can diverge reality to varying degrees. The variability such disagreement within catchments has rarely been examined as a function heterogeneity land cover, soil type, slope in catchment interest....
These hydrogels generated by macromolecular micelles cross-linking have been attracting a lot of attention due to their excellent mechanical properties. In this paper, Pluronic F127 diacrylate (F127DA) macromolecule were prepared and used as cross-linkers prepare polyacrylamide (PAM) hydrogels. The effects the concentration F127DA on morphology, swelling behavior property investigated. results show that high strength extensibility with elongation at break 1320%, fracture stress 528 kPa...
Abstract Spatial pattern of phenology reflects long-term plant adaptation to local environments, yet the drivers these patterns remain understudied. Using satellite data from 2001-2018, this study employed Normalized Difference Vegetation Index (NDVI) for vegetation structural greenness and Solar-Induced Chlorophyll Fluorescence (SIF) functional photosynthesis analyze spring on Qinghai-Tibetan Plateau (hereafter, QTP). A machine learning method, Boosted Regression Trees (BRT), was applied...
East Asia (China, Japan, Koreas and Mongolia) has been the world’s economic engine over at least past two decades, exhibiting a rapid increase in fossil fuel emissions of greenhouse gases (GHGs) expressed recent ambition to achieve climate neutrality by mid-century. However, GHG balance its terrestrial ecosystems remains poorly constrained. Here, we present synthesis three most important long-lived (CO2, CH4 N2O) budgets during decades 2000s 2010s, following dual constraint bottom-up...