- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Ultrasound in Clinical Applications
- Cardiac Arrhythmias and Treatments
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Cardiovascular Health and Disease Prevention
- Antiplatelet Therapy and Cardiovascular Diseases
- Peripheral Artery Disease Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cerebrovascular and Carotid Artery Diseases
- Cardiomyopathy and Myosin Studies
- Cardiac pacing and defibrillation studies
- Labor Movements and Unions
- Cardiac, Anesthesia and Surgical Outcomes
- Occupational and Professional Licensing Regulation
- Atrial Fibrillation Management and Outcomes
Tufts University
1994-2023
Tufts Medical Center
2014-2023
Beth Israel Deaconess Medical Center
2016
Icahn School of Medicine at Mount Sinai
2016
Doctors Company (United States)
2016
Michigan CardioVascular Institute
2016
The Cardiac and Vascular Institute
2016
Soroka Medical Center
2016
Bayfront Medical Center
2013
Signature Research (United States)
2013
Right ventricular dysfunction (RVD) is a major cause of morbidity and mortality in the setting acute inferior wall myocardial infarction (IWMI), early detection may improve clinical outcomes. We defined novel hemodynamic index, pulmonary artery pulsatility index (PAPi), explored whether PAPi correlates with severe RVD IWMI.From 2008 to 2010, we identified 20 patients presenting angiographically confirmed proximal right coronary occlusion suspected (sRVD) as by instability, profound...
We evaluated the clinical applicability of a prototype tomographic transesophageal echocardiographic (TEE) system, which not only provides conventional TEE images but also three‐dimensional tissue reconstruction and four‐dimensional display capabilities. The probe was used in 16 patients laboratory, intensive care unit, operating room. instrument is 5‐MHz, 64‐element, phased array unit mounted on sliding carriage within casing. After appropriate placement esophagus, straightened, balloon...
Background: The outcome of medically refractory patients with obstructive hypertrophic cardiomyopathy treated according to the American College Cardiology/American Heart Association consensus guideline recommendations is not known. objectives this study were define short- and long-term outcomes undergoing alcohol septal ablation (ASA) surgical myectomy (SM) patient management in accordance these guidelines, as well quantify procedural risk burden comorbid conditions at time treatment....
Bivalirudin, a direct thrombin inhibitor, is widely used adjunctive therapy in patients undergoing percutaneous intervention (PCI). Thrombin highly potent agonist of platelets and activates the protease-activated receptors, PAR1 PAR4, but it not known whether bivalirudin exerts antiplatelet effects PCI patients. We tested hypothesis that acts as an agent by preventing activation PARs on platelet surface.The effect function systemic levels was assessed elective PCI. Mean plasma were 2.7±0.5...
Multiplane transesophageal echocardiography is a new exciting development in echocardiography. We examined the methodology and echo‐anatomic correlations of multiplane its clinical applications 100 patients. used 5‐MHz phased array (OmniPlane) probe. In this instrument, transducer can be steered through 180° from any location. This provides vast assembly imaging planes, allowing for detailed visualization all dimensions cardiac anatomy. report presents our observations on echocardiographic...
Intravascular ultrasound imaging is a promising new method for assessing vascular morphology. We evaluated the capability of intravascular to quantify pulmonary artery (PA) morphology in vitro and explored feasibility vivo PA animals humans. In study 15 segments, we used 20-MHz prototype catheter. (y) provided crisp images segments demonstrated excellent correlations with anatomic measurements (x) estimation luminal area (y = 0.89x + 2.95, r 0.99, p less than 0.001), diameter (n 30, y 0.79x...
Epidemiology data for lower-extremity arterial thromboembolism (LET) are limited and may result from either acute limb ischemia or an exacerbation of critical ischemia. Given marked changes in both diagnosis therapy over the last 2 decades, we hypothesized that this time period would have witnessed reductions incidence in-hospital mortality LET.Data 1988 through 2007 National Hospital Discharge Survey were analyzed. All admissions patients with LET extracted, respective International...
Discusses the correlation between business cycle and strike activity of trade unions. Background study by Albert Rees which revealed a positive strikes cycle; Analysis theory Theodore Levitt regarding activities. (Abstract copyright EBSCO.)
The traditional transthoracic and transesophageal echocardiographic examination have proven to be useful imaging tools for studying cardiac morphology, pathology, function. Recently, catheter‐based ultrasound transducers been available intravascular ultrasonic imaging. We supposed that performed from within the heart itself can provide information about structure function, especially in settings where or echocardiography may technically difficult perform poorly tolerated by patient. To...
Analysis of the licensing requirements in barbering profession United States. Economic impacts effective occupational licensing; Effects barber on supply barbers; Changes provision. (Abstract copyright EBSCO.)
Early recognition of an acute coronary occlusion (ACO) improves clinical outcomes. Soluble fms-like tyrosine kinase-1 (sFLT1) is endothelium-derived protein induced by hypoxia. We tested whether sFLT1 levels are elevated in ACO.Serum were measured enzyme-linked immunosorbent assay patients with ST-segment elevations and angiographically confirmed ACO, unstable angina/non elevation myocardial infarction, 2 control groups. To further explore release, a mouse model ACO vitro human artery...
Background— Peripheral vascular interventions are increasingly preferred for the treatment of patients with symptomatic peripheral arterial disease because they associated similar clinical outcomes and lower morbidity than open surgical procedures. The objective this study was to assess comparative effectiveness procedural anticoagulation bivalirudin compared unfractionated heparin in undergoing interventions. Methods Results— This a retrospective, observational using Premier Hospital...