A5005822510- Parasitic Infections and Diagnostics
- Ion channel regulation and function
- Humic Substances and Bio-Organic Studies
- Toxoplasma gondii Research Studies
- Garlic and Onion Studies
- Insect Pest Control Strategies
- Plant-derived Lignans Synthesis and Bioactivity
- Parasites and Host Interactions
- Probiotics and Fermented Foods
- Insect and Pesticide Research
- Plant Disease Management Techniques
- Cytomegalovirus and herpesvirus research
- Viral gastroenteritis research and epidemiology
- Flame retardant materials and properties
- Amoebic Infections and Treatments
- Synthesis and Biological Evaluation
- Magnesium Oxide Properties and Applications
- Layered Double Hydroxides Synthesis and Applications
- Helminth infection and control
- Antimicrobial Peptides and Activities
- Escherichia coli research studies
- Parasite Biology and Host Interactions
- Advanced ceramic materials synthesis
Universidad de Guadalajara
2017-2023
Abstract Wood is one of the most versatile materials, including religious symbols and carved works art. However, it a material that vulnerable to biodeterioration by insects, fungi, other organisms. Biodeterioration xylophagous insects main problems for conservation wooden objects; however, control methods are focused on insecticides which can be harmful toxic humans environment. In this work, use zinc oxide nanoparticles obtained green synthesis with an aqueous extract agro-industrial waste...
Giardia lamblia is a worldwide protozoan responsible for significant number of intestinal infections. There are several drugs the treatment giardiasis, but they often cause side effects. Curcumin, component turmeric, has antigiardial activity; however, molecular target and mechanism antiproliferative activity not clear. The effects curcumin on cellular microtubules have been widely investigated. Since tubulin most abundant protein in cytoskeleton Giardia, to elucidate whether against this...
Abstract Objectives Curcumin (CUR) has well-known activity against cancer cells and parasites; however, its applications are limited since this is an unstable molecule, which may suffer degradation by light temperature, also, the low water solubility reduce bioavailability. Layered double hydroxides (LDH) materials owing to excellent anion exchange capacity, good biocompatibility toxicity. Methods nanoparticles prepared with zinc magnesium cations were used as a vehicle for CUR in Caco-2,...
Giardiasis, a diarrheal disease, is highly prevalent in developing countries. Several drugs are available for the treatment of this parasitosis; unfortunately, all them have variable efficacies and adverse effects. Bursera fagaroides has been known its anti-inflammatory antidiarrheal properties Mexican traditional medicine. We investigated vitro anti-giardial activities four podophyllotoxin-type lignans from var. fagaroides, namely, 5′-desmethoxy-β-peltatin-A-methylether (5-DES),...
Pet and EspC are toxins secreted by enteroaggregative (EAEC) enteropathogenic (EPEC) diarrheagenic Escherichia coli pathotypes, respectively. Both members of the Serine Protease Autotransporters Enterobacteriaceae (SPATEs) family. important virulence factors that produce cytotoxic enterotoxic effects on enterocytes. Here, we evaluated effect curcumin, a polyphenolic compound obtained from rhizomes Curcuma longa L. (Zingiberaceae) secretion proteins. We found curcumin prevents without...
Background Diarrheal diseases caused by protozoa have a great impact on human health around the world. Giardia lamblia is one of most common flagellates in intestinal tract. Factors such as adverse effects to first-line drugs or appearance drug-resistant strains, make it necessary identify new treatment alternatives. Agroindustry waste, like pomegranate peel, are source phenolic compounds, which possess antiparasitic activities. In vivo studies demonstrated antigiardiasic potential reducing...
There are several drugs for the treatment of giardiasis; however, there is a tendency patients to abandon because drug-related adverse effects, resulting in relapses, acquired resistance, and higher rates failure. Recently, we reported some podophyllotoxin-type lignans from Bursera fagaroides var. showing antigiardial activity. In present work, demonstrated that 5'-desmethoxy-peltatin-A-methylether (5-DES), acetylpodophyllotoxin (APOD), podophyllotoxin (POD) affect distribution staining...
Background The protozoan Giardia lamblia is the causal agent of giardiasis, one main diarrheal infections worldwide. Drug resistance to common antigiardial agents and incidence treatment failures have increased in recent years. Therefore, search for new molecular targets drugs against infection essential. In protozoa, ionic channels roles their life cycle, growth, stress response. Thus, they are promising drug design. strategy ligand-protein docking has demonstrated a great potential...