Xin Y. Mei

ORCID: 0000-0001-9251-4583
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About
Contact & Profiles
Research Areas
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Hip disorders and treatments
  • Osteoarthritis Treatment and Mechanisms
  • Hip and Femur Fractures
  • Blood transfusion and management
  • Drug Transport and Resistance Mechanisms
  • Knee injuries and reconstruction techniques
  • Nanocomposite Films for Food Packaging
  • Antifungal resistance and susceptibility
  • Bone and Joint Diseases
  • Esophageal Cancer Research and Treatment
  • Shoulder and Clavicle Injuries
  • Polysaccharides Composition and Applications
  • Pharmacogenetics and Drug Metabolism
  • Optical Imaging and Spectroscopy Techniques
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Radiomics and Machine Learning in Medical Imaging
  • Fungal Infections and Studies
  • Renal cell carcinoma treatment
  • Skin Protection and Aging
  • Glycosylation and Glycoproteins Research
  • Dyeing and Modifying Textile Fibers
  • Opioid Use Disorder Treatment

Zhejiang A & F University
2025

University of Toronto
2019-2023

Anhui Provincial Hospital
2023

University of Science and Technology of China
2023

Shanghai Medical Information Center
2022

Mount Sinai Hospital
2018-2021

Sinai Hospital
2019-2021

Toronto East General Hospital
2021

China Resources (China)
2020

Wuhan University of Science and Technology
2020

Aims The aim of this study was to report the outcome femoral condylar fresh osteochondral allografts (FOCA) with concomitant realignment osteotomy a focus on graft survivorship, complications, reoperation, and function. Patients Methods We identified 60 patients (16 women, 44 men) who underwent unipolar FOCA between 1972 2012. mean age 28.9 years (10 62) follow-up 11.4 (2 35). Failure defined as conversion total knee arthroplasty, revision allograft, or removal. Clinical evaluated using...

10.1302/0301-620x.101b1.bjj-2018-0407.r1 article EN The Bone & Joint Journal 2019-01-01

Background: Revision hip arthroplasty poses several challenges, including the management of perioperative blood loss. Recent studies have validated use tranexamic acid in primary total arthroplasty, showing reduced loss and decreased number allogenic transfusions. The effectiveness has not been well studied revision setting. Methods: We performed a retrospective review 1,072 patients who underwent at our institution from 2008 to 2016. A 634 met inclusion criteria, comparisons were made...

10.2106/jbjs.17.01212 article EN Journal of Bone and Joint Surgery 2018-09-05

GM1 gangliosidosis is a rare, inherited neurodegenerative disorder caused by mutations in the GLB1 gene, which encodes lysosomal hydrolase acid β-galactosidase (β-gal). β-gal deficiency leads to toxic accumulation of ganglioside, predominantly central nervous system (CNS), resulting progressive neurodegeneration. LYS-GM101 an AAVrh.10-based gene therapy vector carrying human cDNA. The efficacy intra-cerebrospinal fluid injection analogs was demonstrated mouse and cat models with widespread...

10.1016/j.omtm.2022.10.004 article EN cc-by-nc-nd Molecular Therapy — Methods & Clinical Development 2022-10-07

Objective: To investigate the role of prediction microvascular invasion (mVI) in hepatocellular carcinoma (HCC) by 18F-FDG PET image texture analysis and hybrid criteria combining PET/CT multi-parameter MRI. Materials methods: Ninety-seven patients with HCC who received examinations MRI were retrospectively included this study randomized into training testing cohorts. The lesion features extracted using MaZda software. optimal predictive mVI selected, classification procedure was conducted....

10.3389/fphys.2022.928969 article EN cc-by Frontiers in Physiology 2022-08-12

Surgeon clinical practice variation and patient preferences during the informed consent discussion: a mixed-methods analysis in lumbar spine surgery Background: Patients with disc herniation may greatly benefit from microdiscectomy.Although surgeons performing microdiscectomy routinely obtain consent, potential adverse events they disclose often vary.Moreover, little is known about what disclosures are deemed most valuable by patients.The aim of this study was to determine variations among...

10.1503/cjs.005619 article EN Canadian Journal of Surgery 2020-05-21

<h3>Background:</h3> Acetabular component malposition is a major cause of dislocation following total hip arthroplasty (THA). Intellijoint HIP an imageless navigation tool that has been shown to provide accurate intraoperative measurement cup position during primary THA without substantially increasing operative time. However, its accuracy in revision not evaluated. This study therefore aims assess the measuring inclination and anteversion comparison with computed tomography (CT) THA....

10.1503/cjs.012420 article EN Canadian Journal of Surgery 2021-08-01

Summary We report a case of chromoblastomycosis due to the presence large plaque and verrucous hyperplasia lesions on left upper limb, with elbow abnormal activities, in 56‐year‐old male. The diagnosis was based gross microscopic morphologies, histopathological examination clinical manifestation. Molecular tools were applied identifying causative agent Fonsecaea nubica , which is rarely reported be associated chromoblastomycosis. patient initially treated orally terbinafine (250 mg/day)...

10.1111/myc.12732 article EN Mycoses 2017-11-25

Objective: To compare the clinical efficacy of artificial femoral head replacement and Proximal nail antirotation (PFNA) in treatment unstable intertrochanteric fractures elderly. Methods: This study retrospectively analyzed 60 elderly patients with treated PFNA from 2015.06 to 2018.06, which 34 were group (Group A) 26 B). Statistical analysis relevant surgical indicators such as time, intraoperative blood loss, postoperative transfusion, time landing, infection rate, hospital stay, number...

10.4236/ijcm.2020.114014 article EN International Journal of Clinical Medicine 2020-01-01

The past two decades have seen a significant increase in consequences associated with nonmedical misuse of prescription opioids, such as addiction and unintentional overdose deaths. This study aimed to use an electronic survey assess attitudes opioid-prescribing practices Canadian orthopaedic surgeons trainees following open reduction internal fixation (ORIF) distal radius ankle fractures. was the first these factors ORIF fractures using design.A 40-item developed focusing on four themes:...

10.1155/2023/9968219 article EN cc-by Advances in Orthopedics 2023-09-07
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