- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Advanced X-ray and CT Imaging
- Radiopharmaceutical Chemistry and Applications
- Management of metastatic bone disease
- Meningioma and schwannoma management
- Radiomics and Machine Learning in Medical Imaging
- Nuclear Engineering Thermal-Hydraulics
- Nuclear Physics and Applications
- Quality and Safety in Healthcare
- Risk and Safety Analysis
- Radiation Therapy and Dosimetry
- Neurofibromatosis and Schwannoma Cases
- Soft tissue tumors and treatment
- Vascular Malformations Diagnosis and Treatment
Northwell Health
2020-2024
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2022-2023
Hofstra University
2022
Rhode Island Hospital
2022
Brown University
2022
Memorial Sloan Kettering Cancer Center
2001-2007
Mercy Medical Center
2005-2007
South Nassau Communities Hospital
2006
Mercy Medical Center
2001-2003
Currently the Gamma Knife system is accompanied with a treatment planning system, Leksell GammaPlan (LGP) which standard, computer-based for radiosurgery. In LGP, dose calculation algorithm does not consider scatter contributions and inhomogeneity effect due to skull air cavities. To improve accuracy, Monte Carlo simulations have been implemented system. this work, 201 Cobalt-60 sources in unit are considered same activity. Each source contained cylindric stainless steel capsule. The...
Abstract The objective of this work was to identify the exact location effective point measurement (EPM) four different active detectors compare relative collimator output factors (ROF) Leksell Gamma Knife (LGK) according IAEA TRS‐483 recommendations. ROF measured at center spherical LGK‐Solid Water (LGK‐SW) Phantom for three (4‐, 8‐, and 16‐mm in diameter) collimators using (PTW‐TN60008, PTW‐TN60016, PTW‐TN60017, PTW‐60019 diode/diamond) detectors. Since diode have a much smaller sensitive...
Plan checks are important components of a robust quality assurance (QA) program. Recently, the American Association Physicists in Medicine (AAPM) published two reports concerning plan and chart checking, Task Group (TG) 275 Medical Physics Practice Guideline (MPPG) 11.A. The purpose current study was to crosswalk initial check failure modes revealed TG against our institutional QA program local incident reporting data. Ten physicists reviewed 46 high-risk reported Table S1.A.i report....
INTRODUCTION: Stereotactic radiosurgery is established as the optimal treatment modality for metastatic disease of brain, but there ongoing debate about larger brain metastases. There have been few studies identifying and quantifying lesion characteristics where efficacy local control these lesions suffer. METHODS: We retrospectively identified patients who received surgical resection and/or hypofractionated Gamma Knife (HF-GKRS) between 2017 2022 tumors greater than 10cc. Clinical,...
Abstract In 2022, we incorporated the Lightening optimizer software into our Gamma Knife treatment planning workflow. This allows for rapid generation of plans based on user selected parameters. We aimed to compare used before and after incorporation patients with intact breast lung metastases identify dosimetric differences (gradient index, selectivity coverage) clinical outcomes (radionecrosis local control). also subdivided lesions by size, defining small as <1cc, medium 1 4 cc,...
Abstract Paragangliomas present a challenge for stereotactic radiosurgery (SRS) treatment planning, particularly regarding the delineation of tumor boundaries. We propose that integrating 68Ga-DOTATATE PET scans alongside MRI in SRS planning will facilitate superior target identification and coverage compared to reliance on alone. A retrospective analysis 9 patients diagnosed with paraganglioma who underwent imaging over 20-month period was conducted. Images were imported into GammaPlan...
Abstract Stereotactic radiosurgery (SRS) is being increasingly employed in the treatment of brain metastases. The evidence radiological response metastatic lesions from gynecological primary lacking literature. To assess rate to gamma knife SRS over a longitudinal follow-up period, single centre prospectively maintained database was analysed retrospectively 2014 2024. Lesion volumes were contoured at each follow up scan using Leksell Gammaplan software. Response assessment neuro-oncology...
Purpose: To investigate the possible dose perturbation from head frame which is attached to patient skull provide precise location of target in brain and not considered during calculation Gamma Knife SRS. Method Materials: An EGS4 based Monte Carlo simulation was applied In simulation, geometries stationary collimator helmet were reconstructed exactly according Model C. The materials collimators selected as close original possible. All particles traced through until they pass inner surface...
Purpose: To verify the dosimetry accuracy for MRI‐based planning of Gamma Knife Stereotactic Radiosurgery. Method and Materials: In Monte Carlo simulation, unit geometry was reconstructed exactly as original unit. Materials were selected close to actual one possible. Patients scanned on both a CT 1.5 T MRI scanner. Simulations performed these patients using homogeneous based MRI, heterogeneous built numbers or different densities MR contoured skull structures. The homogenous density chosen...
Purpose: To study the inhomogeneity effect from skull and air cavity on Gamma Knife Stereotactic Radiosurgery. Method Materials: Patient CT data procedure was used in a Monte Carlo simulation. In simulation, 201 Cobalt‐60 sources were considered to have same activity. Each source contained cylindric stainless steel capsule. The beam stored four phase‐space files which generated inner side for each of 4 treatment helmets, after Cobalt passed through primary collimator secondary collimator....
Objective To improve the efficiency of frame-based and frameless Gamma Knife® Icon™ (GKI) treatments by analyzing workflows both treatment approaches identifying steps that lead to prolonged patient in-clinic or time. Methods The processes 57 GKI patients, 16 41 cases were recorded analyzed. For treatments, time points for various in process, including check-in, magnetic resonance imaging (MRI) completion, plan approval, start/end times. required completing each step was calculated...