A5040384996- Lipid Membrane Structure and Behavior
- Microwave Engineering and Waveguides
- Epigenetics and DNA Methylation
- Nanopore and Nanochannel Transport Studies
- Origins and Evolution of Life
- Radio Frequency Integrated Circuit Design
- Supramolecular Self-Assembly in Materials
- Acoustic Wave Resonator Technologies
- Photoreceptor and optogenetics research
- Antenna Design and Analysis
- Block Copolymer Self-Assembly
- Natural Language Processing Techniques
- Smart Grid and Power Systems
- Topic Modeling
- Inflammatory Biomarkers in Disease Prognosis
- Advanced Polymer Synthesis and Characterization
- Supramolecular Chemistry and Complexes
- Conducting polymers and applications
- RNA modifications and cancer
- Advanced Text Analysis Techniques
- Organic Electronics and Photovoltaics
- Intensive Care Unit Cognitive Disorders
- Surfactants and Colloidal Systems
- Sepsis Diagnosis and Treatment
- Security in Wireless Sensor Networks
Beijing National Laboratory for Molecular Sciences
2021-2023
Chinese Academy of Sciences
2012-2023
University of Chinese Academy of Sciences
2018-2023
Molecular Sciences Institute
2023
Hefei University of Technology
2022
Harbin Medical University
2022
Third Affiliated Hospital of Harbin Medical University
2022
Center for Excellence in Molecular Cell Science
2012-2015
Shanghai Institutes for Biological Sciences
2015
Shanghai Electric (China)
2015
A synthetic protocell with subcompartments was designed to mimic cellular signal processing.
Liver and kidney cancers are notorious for drug resistance. Due to the complexity, redundancy interpatient heterogeneity of resistance mechanisms, most efforts targeting a single pathway were unsuccessful. Novel personalized therapies multiple essential pathways in parallel hold promise future cancer treatment. Exploiting multitarget characteristic microRNAs (miRNAs), we developed new therapeutic strategy by combinational use miRNA anticancer drugs increase response. By systems approach,...
Living systems create complex structures and functions by mastering self-organization in a variety of equilibrium non-equilibrium states. Mimicking the dynamical phenomena with synthetic cell-like entities (protocells) under conditions offers an important step toward representation minimum life. Here, cell-sized coacervate microdroplets assembled from associative metallosurfactant coacervation via liquid-liquid phase separation (LLPS) that exhibits behaviors are reported. The...
Abstract As the preliminary synthetic analogs of living cells, protocells with life‐like features serve as a versatile platform to explore origin life. Although constructed from multiple components have been developed, transition primitive cellular compartments toward structural complexity and advanced function remains scientific challenge. Herein, programmable pathway is established exploit simple chemistry construct protocell models emulsion droplets, nanocapsules molecularly crowded...
Dual-specificity phosphatases (DUSPs) are a family of protein that dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues. DUSPs de-regulated in many human diseases, including cancers. However, the function tumorigenesis remains largely unknown. Here, using short hairpin RNA-based gene knockdown, we found several members DUSP play critical roles regulating cell proliferation. In particular, showed DUSP16 ablation leads to G1/S transition arrest, reduced...
Cooperative coacervation of a porphyrin and polycation electrolyte gives birth to photoactive membraneless protocells via liquid-liquid phase separation, where J-aggregates are formed offer energy transduction pathways, rendering an adaptive platform for confining photocatalytic reactions within protocell compartments.
A substrate-integrated waveguide (SIW) miniaturization filter is proposed, which features high attenuation characteristics, effectively reduces loss and size, improves frequency selectivity.The miniaturized using the evanescent-mode theory embeds a nested U-shaped resonator in upper metal surface of SIW.The proposed filter's equivalent circuit structure incorporates two LC parallel resonant loops with resistance characteristics that can, turn, create transmission zeros stopband to enhance...
Generating factual-consistent summaries is a challenging task for abstractive summarization. Previous works mainly encode factual information or perform post-correct/rank after decoding. In this paper, we provide solution from the perspective of contrastive learning, which natural extension previous works. We propose CO2Sum (Contrastive Consistency), learning scheme that can be easily applied on sequence-to-sequence models summarization, proving model fact-aware without modifying...
This paper proposes a hybrid cross-coupled filter that utilizes coplanar waveguide (CPW) resonator and electromagnetic coupling structure.The features flexible controllable position of transmission zeros quasi-elliptical response.It is composed two CPW structures etched within the upper metal surface second-order substrate-integrated (SIW) resonant cavity.By adjusting dimensions between SIW cavities width inductive window, strengths electric magnetic couplings can be easily controlled to...
In order to achieve miniaturization and high performance in microwave filters, this paper proposes two double-layer bandpass filters with different structures, both equivalent square-coupled topologies.These employ dual-cavity single-mode singlecavity dual-mode substrate-integrated waveguide resonators.In configuration, the upper layer comprises resonators connected input output feed lines, while lower contains coupled layer's through slots on middle metal layer.A comprehensive analysis is...
in recent two years, electrical load Fushun District increases continuously, and the impact harmonic pollution on power grid rises voltage quality problem becomes aggravated.Through multi-disciplinary analysis demonstration, Power Supply Company installed SVC/SVG 220kV center substation 66kV terminal 2010 2011 respectively to regulate reactive of system for purpose stabilized less line loss.This paper introduces actual operation situation these sets substations, provides helpful reference...
A novel substrate-integrated waveguide (SIW) dual-mode cavity bandpass filter with a loaded defected ground structure (DGS) is proposed.The SIW operates in two modes, TE 110 and 120 , the field distribution of mode altered by installing metal perturbation aperture middle to bring its resonance frequency close that mode, forming points passband.A DGS embedded at level introduce transmission zero high-frequency rejection band, thus improving performance for band.The simulated measured results...
With the advent of era big data, relevant technical standards wireless sensor networks are becoming more and perfect, so information security will also attract increasing attention. Because once secret network is leaked, it bring huge damage to entire Internet environment, even cause collapse. As a result, privacy problem in has become an urgent be solved. This paper aims study protection from perspective data. Taking data as example, proposes based on analysis characteristics networks,...