A5035454601- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiac tumors and thrombi
- Long-Term Effects of COVID-19
- Anesthesia and Pain Management
- Shoulder Injury and Treatment
- Cardiac and Coronary Surgery Techniques
- Radiomics and Machine Learning in Medical Imaging
- Intracranial Aneurysms: Treatment and Complications
- Respiratory Support and Mechanisms
- Machine Learning in Healthcare
- COVID-19 Clinical Research Studies
- Statistical Methods in Clinical Trials
- Pediatric Pain Management Techniques
- Cardiac Arrest and Resuscitation
- Ultrasound in Clinical Applications
- Non-Invasive Vital Sign Monitoring
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
V.A. Negovsky Scientific Research Institute of General Reanimatology
2021-2025
Vita-Salute San Raffaele University
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2023
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2023
Regional Clinical Research
2020-2022
Moscow Regional Research Institute of Obstetrics and Gynecology
2021
INTRODUCTION: Central venous pressure (CVP) has long been considered one of the most reliable methods for assessing volemic status and responsiveness to infusion therapy in patients intensive care. In recent years, attitudes toward CVP have shifted dramatically, but neither published data nor emergence with proven efficacy significantly changed practicing anesthesiologists' reliance on measurement diagnostic accuracy. OBJECTIVE: The aim this study is assess existing accuracy predicting...
Aim: to study the correlation of immune parameters in breast cancer patients undergoing general anesthesia and evaluate 1-year overall recurrence-free survival after surgery depending on technique. Materials Methods . A post hoc analysis data from a double-blind, randomized, controlled clinical trial involving 98 with operable was performed. Patients were divided into two groups: 48 received inhalational (IA) 50 total intravenous (TIVA). Immune (CRP, IgA, IgM, IgG, C3, C4, MMP-9, neutrophil...
Background/Objectives: Surgical procedures in chronic obstructive pulmonary disease (COPD) patients carry a high risk of postoperative respiratory failure, often causing the need for mechanical ventilation and prolonged intensive care unit (ICU) stays. Accompanying COPD with heart failure further increases complications. This study aimed to identify predictors mortality, ICU hospital stays, ventilation, vasoactive drug usage moderate severe undergoing elective non-cardiac surgery. Methods:...
Breast cancer (BC) mortality primarily stems from metastases rather than the primary tumor itself. Perioperative stress, encompassing both surgical and anesthetic factors, profoundly impacts immune system, leading to alterations in neuroendocrine pathways functions, potentially facilitating progression metastasis. Understanding immunomodulatory effects of different anesthesia techniques is crucial for optimizing perioperative care patients with BC. The neutrophil-to-lymphocyte ratio (NLR)...
<h3></h3> Для того чтобы оценить статистическую значимость полученных результатов и правильно сформулировать заключение выводы исследования, необходимо выбрать адекватные методы статистического анализа, корректно их применить интерпретировать результаты. Описанию основных правил работы с данными посвящена настоящая статья. Информация предназначена врачам научным сотрудникам, делающим первые шаги на научном поприще.
The history of the study postoperative neurocognitive disorders (PND) looks as a long and thorny path more than 400 years. Despite all accumulated data on PND risk factors outcomes, there’s still no complete understanding etiology pathogenesis this complication. Moreover, current anesthesiologyresuscitation practice faces challenges has pending questions in diagnosis classification disorders. purpose review. To contemplate evolution perceptions international medical community (IMC) regarding...
In the era of healthcare digital transformation, scientific community faces need for structured and available datasets research technological projects in field artificial intelligence, related to development new diagnostic treatment methods. Objective: develop a dataset containing anonymized medical data all patients treated at Federal Research Clinical Center Intensive Care Medicine Rehabilitology (FRCCR), provide access doctors scientists FRCCR other centers patient subsequent analysis...
Background: The prevailing model for understanding chronic critical illness is a biphasic model, suggesting phases of acute and conditions. A major challenge within this the difficulty in determining timing process chronicity. It likely that triad symptoms (inflammation, catabolism, immunosuppression [ICIS]) could be associated with particular point. We aimed to explore impact symptom immunosuppression) on outcomes patients hospitalized intensive care units (ICUs). Methods: eICU-CRD database...
The objective: to develop a predictive model for assessing the risk of death in patients with COVID-19 admitted intensive care unit (ICU). Subjects and Methods. This was single-center retrospective cohort study hospital mortality ICU V.P. Demikhov City Clinical Hospital from March 6 June 3, 2020. Results. Case histories 403 were analyzed. In-hospital 30-day among treated 44.9% (181/403 patients). A multivariate analysis showed that significant predictors age 60 years or more (adj. OR 3.84;...
Septic shock, as the most severe form of sepsis, is characterized by high mortality reaching 40% despite use modern standards diagnosis and treatment. In thanatogenesis septic vasoplegia plays a leading role, respectively, therapy condition under discussion involves vasoconstrictors, along with standard prescription infusion therapy, antibiotics symptomatic The choice specific vasoactive drug difficult task for practicing anesthetist, undoubtedly positive properties, vasoconstrictors each...
Many patients undergo surgery under general anaesthesia each day. One of the high-priority tasks for an anesthesiologist is to protect tissues from a systemic inflammatory reaction or oxidative distress (including ischaemia/reperfusion). This review aims demonstrate anti-inflammatory and antioxidant properties in experimental clinical studies.Halogenated anaesthetics lead inactivation glycogen synthase kinase-3β (GSK-3β), key enzyme implementation cellular damage mechanisms response syndrome...
<h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Оценить влияние протоколизированно-персонифицированного подхода к управлению гемодинамикой (ППУГ) на 30-дневную летальность и продолжительность пребывания в палате интенсивной терапии (ПИТ) стационаре пациентов пожилого старческого возраста, перенесших обширную операцию органах брюшной полости, определить предикторы летального исхода. <h3>МАТЕРИАЛ И МЕТОДЫ</h3> Проведено ретроспективно-проспективное клиническое исследование эффективности применения ППУГ...
<h3></h3> Имеются многочисленные свидетельства негативного влияния коморбидности на результаты лечения пациентов с новой коронавирусной инфекцией (COVID-19). Однако недостаточно изучена роль заболеваний сердечно-сосудистой системы и особенно вида медикаментозного этой патологии течение основного инфекционного процесса развитие неблагоприятного исхода у данной категории пациентов. <h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Оценить влияние сопутствующих сердечно-сосудистых хронического применения ряда...
Introduction and aim. Recent evidence suggests that inhalation anesthesia (IA) is associated with higher cancer mortality than total intravenous (TIVA), possibly due to a modulation of the immune response. The aim this study was determine impact techniques on selected parameters patient immunity considering relationship between methods status and, consequently, incidence recurrence. Methods. We performed meta-analysis clinical studies published in PubMed, Google Scholar, Cochrane databases,...