A5029537861- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Galectins and Cancer Biology
- Gut microbiota and health
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
- Asthma and respiratory diseases
- Agricultural pest management studies
- COVID-19 Impact on Reproduction
- Barrier Structure and Function Studies
- Infant Nutrition and Health
- Bacteriophages and microbial interactions
- HIV/AIDS drug development and treatment
- Bacterial Infections and Vaccines
- Viral gastroenteritis research and epidemiology
- Infectious Diseases and Tuberculosis
- Plant Pathogenic Bacteria Studies
- Animal Virus Infections Studies
Universitat de Barcelona
2021-2024
Institut de Biomedicina de la Universitat de Barcelona
2021-2024
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2023-2024
Institut de Recerca Sant Joan de Déu
2023-2024
University of Cartagena
2023-2024
Universidad de San Buenaventura, Bogota
2023-2024
Inflammatory bowel disease (IBD) is a chronic inflammatory condition involving dysregulated immune responses and imbalances in the gut microbiota genetically susceptible individuals. Current therapies for IBD often have significant side-effects limited success, prompting search novel therapeutic strategies. Microbiome-based approaches aim to restore balance towards anti-inflammatory mucosa-healing profiles. Extracellular vesicles (EVs) from beneficial microbes are emerging as potential...
Trefoil factor 3 (TFF3) plays a key role in the maintenance and repair of intestinal mucosa. TFF3 expression is upregulated by microbiota through TLR2. At posttranscriptional level, downregulated miR-7-5p. Reduced levels have been detected damaged tissue IBD patients. Here, we investigate regulation extracellular vesicles (EVs) LS174T goblet cells using RT-qPCR inhibitors TLR2 or PI3K pathways. To evaluate subsequent impact on epithelial barrier function, conditioned media from control...
Rotavirus (RV) infection is a major cause of acute gastroenteritis in children under 5 years old, resulting elevated mortality rates low-income countries. The efficacy anti-RV vaccines limited underdeveloped countries, emphasizing the need for novel strategies to boost immunity and alleviate RV-induced diarrhea. This study explores effectiveness interventions involving extracellular vesicles (EVs) from probiotic commensal E. coli mitigating diarrhea enhancing preclinical model RV suckling...
Pseudomonas aeruginosa is a well-known pathogen for its rapid development of multi-drug antibiotic resistance. This responsible numerous human diseases, particularly affecting immunocompromised and elderly patients. Hence, discovering novel therapeutics has become necessary in the fight against antimicrobial study focused on evaluating potential inhibitory activity eleven phytocompounds from Azadirachta indica nucleotide-binding site FtsZ protein P. through cheminformatics approach. an...
PepT1, a proton-coupled oligopeptide transporter, is crucial for intestinal homeostasis. It mainly expressed in small intestine enterocytes, facilitating the absorption of di/tri-peptides from dietary proteins. In colon, PepT1 expression minimal to prevent excessive responses proinflammatory peptides gut microbiota. However, increased colonic linked chronic inflammatory diseases and colitis-associated cancer. Despite promising results animal studies on benefits extracellular vesicles (EVs)...
Introduction Pneumocystis jirovecii pneumonia (PJP) is a well-known and frequent opportunistic infection in HIV patients. However, there has been an increase the number of reports PJP other immunosuppressed patients with autoimmune inflammatory disorders or because chemotherapy high doses steroids, especially when used combination as part immunosuppressive therapy. Objective Despite increasing importance non-HIV patients, lack comprehensive updated information on epidemiology, pathogenesis,...
Abstract Introduction Pneumocystis jirovecii pneumonia (PJP) is a well-known and frequent opportunistic infection in HIV patients. However, there has been an increase the number of reports PJP other immunosuppressed patients with autoimmune inflammatory disorders or because chemotherapy high doses steroids, especially when used combination as part immunosuppressive therapy. Objective Despite increasing importance non-HIV patients, lack comprehensive updated information on epidemiology,...