A5003423249- Advanced Measurement and Metrology Techniques
- Advanced X-ray Imaging Techniques
- Force Microscopy Techniques and Applications
- Health Systems, Economic Evaluations, Quality of Life
- Surface Roughness and Optical Measurements
- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Medication Adherence and Compliance
- Organ Transplantation Techniques and Outcomes
- Bone health and osteoporosis research
- Hip and Femur Fractures
- Statistical Methods in Clinical Trials
- Pharmaceutical Economics and Policy
- Pharmaceutical Practices and Patient Outcomes
- Peripheral Artery Disease Management
- Mechanical and Optical Resonators
- Statistical Methods and Inference
- Advanced Surface Polishing Techniques
- Particle Accelerators and Free-Electron Lasers
- Transplantation: Methods and Outcomes
- Palliative Care and End-of-Life Issues
- Hormonal Regulation and Hypertension
- Blood Pressure and Hypertension Studies
- Bipolar Disorder and Treatment
- Crystallography and Radiation Phenomena
Stanford University
2016-2025
Stanford Medicine
2017-2021
Stanford Health Care
2018
National Cancer Institute
2013-2014
National Institutes of Health
2014
Azienda Sanitaria di Firenze
2013
Istituti di Ricovero e Cura a Carattere Scientifico
2013
Institute for Research on Population and Social Policies
2013
National Research Council
2013
Istituto Oncologico Veneto
2013
Cationic lipid-mediated gene transfer to the mouse lung induces a dose-dependent inflammatory response that is characterized by an influx of leukocytes and elevated levels cytokines interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha), interferon gamma (IFN-gamma). We have examined contribution plasmid DNA (pDNA) this observed toxicity, specifically role unmethylated CpG dinucleotides, which been previously shown be immunostimulatory. report here complexes cationic lipid GL-67 pDNA...
Resistant hypertension is associated with higher rates of cardiovascular disease, kidney and death than primary hypertension. Although clinical practice guidelines recommend screening for aldosteronism among persons resistant hypertension, are unknown. We identified 145 670 excluded congestive heart failure or advanced chronic disease. Among this cohort, we studied 4660 ages 18 to <90 from the years 2008 2014 available laboratory tests within following 24 months. The rate in was 2.1%....
Background: There is limited population-based literature on rates and risk factors for revision following primary total hip replacement. Methods: We performed a retrospective cohort study of Medicare beneficiaries who had elective replacement osteoarthritis between July 1, 1995, June 30, 1996. Patients were followed with use claims through 2008. The end point was as indicated by hospital discharge codes according to the International Classification Diseases, Ninth Revision. used Kaplan-Meier...
Adolescent and young adults (AYAs) face challenges in having their cancers recognized, diagnosed, treated, monitored. Monitoring AYA cancer survival is of interest because the lack improvement outcome previously documented for these patients as compared with younger older patient outcomes. 15-39 years old, diagnosed during 2000-2008 malignant were selected from SEER 17 registries data. Selected analyzed incidence five-year relative by histology, stage, receptor subtypes. Hazard ratios...
Importance Testing for coronary heart disease (CHD) in asymptomatic kidney transplant candidates before is widespread and endorsed by various professional societies, but its association with perioperative outcomes unclear. Objective To estimate the of pretransplant CHD testing rates death myocardial infarction (MI). Design, Setting, Participants This retrospective cohort study included all adult, first-time recipients from January 2000 through December 2014 US Renal Data System at least 1...
Background: Electronic prescribing (e-prescribing) with formulary decision support (FDS) prompts prescribers to prescribe lower-cost medications and may help contain health care costs.In April 2004, 2 large Massachusetts insurers began providing an e-prescribing system FDS community-based practices.Methods: Using 18 months (October 1, 2003, March 31, 2005) of administrative data, we conducted a prepost study concurrent controls.We first compared the change in proportion prescriptions for 3...
Historically, histologic grade has not been considered a useful prognostic factor in head and neck squamous cell carcinoma (SCC). However, other solid tumors, is known to affect prognosis. We test the hypothesis that an independent predictor of prognosis oral cavity SCC.Population-based cohort study using Surveillance, Epidemiology, End Results (SEER) database National Cancer Institute.Fifteen year cause-specific survival. Multivariate analysis was performed on subset patients diagnosed...
Trimethylamine N-oxide (TMAO), a compound derived from byproducts of intestinal bacteria, has been shown to accelerate atherosclerosis in rodents. To date, there are conflicting data regarding the association serum TMAO with cardiovascular outcomes patients ESKD, population exhibiting both high and excessive atherosclerosis.We measured baseline concentrations subset participants (n=1243) Evaluation Cinacalcet Hydrochloride Therapy Lower Cardiovascular Events (EVOLVE) trial conducted post hoc...
Background: Little information is available on the comparative effectiveness of osteoporosis pharmacotherapies. Objective: To compare relative treatments to reduce nonvertebral fracture risk among older adults. Design: Cohort study. Setting: Enrollees in 2 statewide pharmaceutical benefit programs for persons age 65 years or older. Patients: 43 135 new recipients oral bisphosphonates, nasal calcitonin, and raloxifene who began treatment from 2000 2005. The mean was 79 (SD, 6.9), 96% were...
To compare prospectively and retrospectively defined benchmarks for the quality of end-of-life care, including a novel indicator use opiate analgesia.Linked claims cancer registry data from 1994 to 2003 New Jersey Pennsylvania were used examine prospective retrospective seniors with breast, colorectal, lung, or prostate who participated in state pharmaceutical benefit programs.Use opiates, particularly long-acting was low both cohorts (9.1% 10.1%, respectively), which supported underuse...
Abstract Objective Among rheumatoid arthritis (RA) patients who have had the disease for 10 years, more than half focal erosions, and risk of fracture is doubled. However, there little information about potential relationship between erosions bone mineral density (BMD). The aim this study was to determine whether lower BMD associated with higher erosion scores among RA. Methods We enrolled 163 postmenopausal women RA, none whom were taking osteoporosis medications. Patients underwent dual...
Background: ‘Life Years from Transplant’ (LYFT) is a measure of the predicted difference between expected lifespan with and without kidney transplant. The metric was originally proposed in 1999; since then, demographics transplant candidate population have materially changed. Methods: Using contemporary SRTR data, we propose more sophisticated methods for estimating LYFT focus on older candidates, growing sector current pool. We examine trends 1995 to 2020. Results: show that among patients...
Randomized trials aimed at improving the quality of medical care often randomize provider. Such are frequently embedded in health systems with available automated records, which can be used to enhance design trial.We consider how information from records address each following concerns a trial: whether individual providers or practices; clustering outcomes among patients same practice and its impact on study size; expected heterogeneity adherence response intervention; eligibility criteria...