A5057432410- Plant tissue culture and regeneration
- Transgenic Plants and Applications
- Alkaloids: synthesis and pharmacology
- Plant biochemistry and biosynthesis
- Natural Antidiabetic Agents Studies
- Computational Drug Discovery Methods
- Cancer Genomics and Diagnostics
- Gene expression and cancer classification
- Essential Oils and Antimicrobial Activity
- Bioinformatics and Genomic Networks
- Microbial Natural Products and Biosynthesis
- Nanoparticles: synthesis and applications
- Plant Parasitism and Resistance
- Mycotoxins in Agriculture and Food
- Free Radicals and Antioxidants
- Toxin Mechanisms and Immunotoxins
- CRISPR and Genetic Engineering
- Fungal Biology and Applications
- Trace Elements in Health
- Pharmacogenetics and Drug Metabolism
- Medicinal Plants and Bioactive Compounds
- Plant Pathogens and Fungal Diseases
- Photosynthetic Processes and Mechanisms
- Heavy Metal Exposure and Toxicity
- Mycorrhizal Fungi and Plant Interactions
Quaid-i-Azam University
2020-2022
Abstract Background Diabetes mellitus is a chronic disease characterized by hyperglycemia that may occur due to genetic, environmental or lifestyle factors. Natural remedies have been used treat diabetes since long and many antidiabetic compounds of varied efficacies isolated from medicinal plants. Rhazya stricta has for decades the treatment associated ailments. Considering folkloric use R. against diabetes, it was aimed investigate effectiveness its root extracts through in vitro assays...
A worldwide increase in the incidence of fungal infections, emergence new strains, and antifungal resistance to commercially available antibiotics indicate need investigate treatment options for diseases. Therefore, interest exploring activity medicinal plants has now been increased discover phyto-therapeutics replacement conventional drugs. The study was conducted explore identify mechanism action agents edible plants, including
Pelargonium graveolens, rose-scented geranium, is commonly used in the perfume industry. P. graveolens enriched with essential oils, phenolics, flavonoids, which account for its tremendous biological activities. Laser light treatment and arbuscular mycorrhizal fungi (AMF) inoculation can further enhance phytochemical content a significant manner. In this study, we aimed to explore synergistic impact of these two factors on graveolens. For this, four groups surface-sterilized seeds: (1)...
Herbal and traditional medicines can play a pivotal role in combating cancer neglected tropical diseases. Ajuga bracteosa, family Lamiaceae, is an important medicinal plant. The genetic transformation of A. bracteosa with rol genes Agrobacterium rhizogenes further enhances its metabolic content. This study aimed at undertaking the molecular, phytochemical, vitro biological analysis extracts. We transformed plant raised regenerants from hairy roots. Transgenic integration expression rolB were...
The use of natural products as therapeutic agents is rapidly growing recently. In the current study, we investigated protective effects green tea supplementation on lead-induced toxicity in mice. Forty albino mice were divided into four groups follows: A: control group; B: receiving C: lead-intoxicated and D: group supplemented with tea. At end experiment, animals tested for neurobehavioral biochemical alterations. Green was analyzed through Gas Chromatography-Mass Spectrometry (GC/MS)...
Ajuga bracteosa Wall. ex Benth. is an endangered medicinal herb traditionally used against different ailments. The present study aimed to create new insight into the fundamental mechanisms of genetic transformation and biological activities this plant. We transformed A. plant with rol genes Agrobacterium rhizogenes raised regenerants from hairy roots. These transgenic were screened for in vitro antioxidant activities, a range vivo assays, elemental analysis, polyphenol content,...
The rol oncogenes of Agrobacterium rhizogenes enhance the production medicinally important compounds in plants and provide a first barrier against overproduction reactive oxygen species during biotic abiotic stress. This study was designed to evaluate expression genes involved biosynthetic pathways their impact on metabolic contents environmental stress tolerance regenerated Ajuga bracteosa Wall. ex Benth. After successful transformation, real-time quantitative PCR confirmed increased...
Abstract Ajuga bracteosa Wall. ex Benth is an endangered medicinal herb used against different ailments in folklore medicines. Here, we aimed to create a new insight the fundamental mechanisms of genetic transformation ethnomedicinal usage this plant. We transformed plant with rol genes Agrobacterium rhizogenes and raised regenerants from hairy roots. The transgenic were screened for vitro antioxidant activities, range vivo assays, linked activities elemental analysis, polyphenol content...
The present study aimed to screen the Rhazya stricta Decne root for its antihyperglycemic and antioxidants potential through in-vitro assays along with phytochemical elemental analyses. crude extract was prepared maceration fractionated using solvent-solvent extraction technique. spectroscopic studies indicated presence of various classes in fractions. antioxidant showed notable results a good concentration phenolic flavonoid contents. Enzyme inhibition demonstrated glucose-lowering effects...