A5078662215- Hypothalamic control of reproductive hormones
- Ovarian function and disorders
- COVID-19 diagnosis using AI
- Plant Reproductive Biology
- Sperm and Testicular Function
- Regulation of Appetite and Obesity
- Liver Disease Diagnosis and Treatment
- Animal Nutrition and Physiology
- Hepatitis B Virus Studies
- Seed Germination and Physiology
- Lung Cancer Diagnosis and Treatment
- Hepatitis C virus research
- Enzyme Production and Characterization
- Alkaloids: synthesis and pharmacology
- Radiomics and Machine Learning in Medical Imaging
- Enzyme function and inhibition
- Livestock and Poultry Management
- Reproductive Biology and Fertility
- Rabbits: Nutrition, Reproduction, Health
- Effects of Environmental Stressors on Livestock
- Ecology and biodiversity studies
- Microplastics and Plastic Pollution
- Internet of Things and AI
- Smart Systems and Machine Learning
- Genetic and phenotypic traits in livestock
Ludwig-Maximilians-Universität München
2025
Zimmer Biomet (Germany)
2025
Rawalpindi Women University
2022-2024
Chitkara University
2022-2024
Rawalpindi Medical University
2022-2024
University of Gujrat
2019-2023
Quaid-i-Azam University
2012-2022
Shaheed Benazir Bhutto Women University
2020
Bahauddin Zakariya University
2019
University of Otago
2012
Tyrosinase and its related proteins are responsible for pigmentation disorders, inhibiting tyrosinase is an established strategy to treat hyperpigmentation. The carbonyl scaffolds can be effective inhibitors of activity, the fact that both benzoic cinnamic acids safe natural substances with such a scaffolded structure, it was speculated hydroxyl-substituted acid derivatives may exhibit potent inhibitory activity. These moieties were incorporated into new chemotypes displayed in vitro effect...
Incidents of breast cancer (BC) are on the rise a daily basis and have proven to be most prevelant cause death for women in both developed developing countries. Among total BC cases diagnosed after menopause, 70% Estrogen Receptor (ER) positive (ER-positive or ER+). Mutations LBD (ligand-binding domain) ER recently been reported major resistance potent antagonists. In this study, experimentally mutations K303R, E380Q, V392I, S463P, V524E, P535H, P536H, Y537C, Y537N, Y537S, D538G were...
Background/Objectives: physical activity (PA) in children offers lifelong benefits, yet nearly four five are insufficiently active. We examined sex-specific differences sport participation by type and its association with weight status. Methods: the ongoing hand-on-heart-study (“Hand-aufs-Herz”), comprehensive data on sociodemographic profiles, PA, anthropometry were collected from 922 school-aged children, adolescents, young adults (8–20 years) Germany. Sex-specific participation, types,...
Kisspeptin and its G-protein coupled receptor Gpr54 are essential for the pubertal activation of gonadotrophin-releasing hormone (GnRH) neurones, with mutation or deletion resulting in failed puberty infertility humans mice. The number kisspeptin-immunoreactive neurones rostral periventricular area third ventricle (RP3V) increases during development concert appearance kisspeptin appositions GnRH mouse preoptic area. We recently demonstrated that increase RP3V neuronal females is dependent...
This research paper aims to focus on the moral cluster production of lung cancer in lungs information and breaks down presentation segment-based calculations. examination would assist specialists with distinguishing phases malignant growth and, furthermore, upgrade clinical consideration. Lung is type disease that has caused most deaths all kinds people over world. A large portion examined dataset, utilizing calculations track group among little cell or non-little different stages. The...
A series of halo‐substituted mixed ester/amide‐based analogues 4a-l have been prepared as jack bean urease inhibitor, which showed good to excellent inhibition enzyme activity. The role benzoyl moieties and alkyl substituted anilines in inhibitory kinetics was also investigated. alkyl‐substituted 1a–b reacted with chloroacetyl chloride afford intermediates 2a-b , were then different benzoic acids 3a–f prepare the title compounds . chemical structures final products ascertained by FTIR, 1 H...
Osteoarthritis is a major cause of disability in older people; pain considered one the most important signs osteoarthritis, which normally affects weight-bearing joint, especially knee joint. The objective present study was to find out prevalence and effects progressive (OA) on sex steroids male patients district Buner KP, Pakistan. Data collected from 294 OA (Male, 46.18%; Female, 54.76%) at different hospitals through questionnaires, face-to-face interviews blood sampling Buner. Results...
Accurate and fast characterization of the subtype sequences Avian influenza A virus (AIAV) hemagglutinin (HA) neuraminidase (NA) depends on expanding diagnostic services is embedded in molecular epidemiological studies. new approach for classifying AIAV HA NA genes into subtypes using DNA sequence data physicochemical properties proposed. This method simply requires unaligned, full-length, or partial as input. It allows quick highly accurate assignments to H1–H16 N1–N9. For feature...
A series of sulfonamide-bearing azaheterocyclic Schiff base derivatives 3(a-j) were synthesized as carbonic anhydrase inhibitors. The substituted benzene sulfonyl chlorides 1(a-d) reacted with N 2 H 4 to get aromatic hydrazides 2(a-d) . intermediate treated aldehydes afford sulfonamide bases spectral data compounds confirmed the formation final products. inhibitory effects on activity determined, and it was found that derivative 3c exhibited most potent IC 50 <mml:math...
Titanium dioxide nanoparticles (TiO2-NPs) are widely manufactured and can be released into the environment, where they have potential to severely affect fish human health. This study was conducted evaluate effect of TiO2-NPs on growth fingerlings Labeo rohita. were used in different concentrations (1 mg/kg, 10 100 mg/kg 1000 mg/kg) mixed basal feed for a period 12 weeks. The mortality rate recorded once acclimatized, after exposure. length (cm) weight (g) measured time concentration...
Hepatitis C virus (HCV) is considered as "Viral Time Bomb" suggested by the World Health Organization and if it not treated timely, will lead towards cirrhosis hepatocellular carcinoma (HCC).The purpose of present research to study possible risk factors, frequent genotypes HCV its association with different age groups.Suspected blood samples from patients were collected hospitals Lahore, Pakistan. Out 1000 suspected samples, 920 found positive detected Anti-HCV ELISA, CobasR. kit. The...
Hepatitis, a condition of liver’s inflammation that can be self-limiting or, in certain chances, it may lead to liver cancer, fibrosis or cirrhosis. Hepatitis viruses mainly cause hepatitis the world. People with C have predominant chances develop diabetes as HCV virus participates causing type 2 diabetes. causes pathogenesis two ways: either directly destroys β cells pancreas contributes specific autoimmunity cells. The present cross sectional study was done Wazirabad Tahsil Gujranwala...
Abstract The Indian pangolin ( Manis crassicaudata ) is an “endangered” mammal species that restricted to four range countries of Asia. ecology and breeding behavior pangolins poorly understood due a lack scientific data. Due heavy poaching illegal killing, the population has declined drastically in last decade. Considering fact low reproductive output, it needs special conservation measures authentic information about its ecology. We estimated concentrations three hormones from scats using...
Kisspeptin role in metabolism has been implicated recently. However, the nature of signals that may connect body fat/muscle tissues with central nervous system governing energy homeostasis remains to be elucidated.The present study was designed investigate effects peripheral kisspeptin-10 administration on irisin release human males.Kisspeptin-10 administered normal weight (n=8) and obese men. Sequential blood sampling performed for 30 minutes pre 210 post kisspeptin injection at interval....
Embryonic nutrition is a key factor that influences broiler progeny performance with long-lasting nutritional adequacies or insufficiencies in the developmental phase. Objective: To explores effects of in-ovo mineral supplementation day feeding on hatching attributes and chick quality breeders. Methods: About 1400 eggs breeders were selected, categorized into seven experimental groups: one control group, three macro (P, Mg, Ca) groups, micro-mineral (Zn, Mn, Cu) groups. During 12th 18th...