A5063971467- Synthesis and biological activity
- Enzyme function and inhibition
- Synthesis and Characterization of Heterocyclic Compounds
- melanin and skin pigmentation
- Microbial Applications in Construction Materials
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Cholinesterase and Neurodegenerative Diseases
- Computational Drug Discovery Methods
- Biochemical Analysis and Sensing Techniques
- Phytochemicals and Antioxidant Activities
- Phenothiazines and Benzothiazines Synthesis and Activities
- Alkaline Phosphatase Research Studies
- Biochemical and Molecular Research
- Click Chemistry and Applications
- Synthesis and Catalytic Reactions
- Politics and Conflicts in Afghanistan, Pakistan, and Middle East
- Quinazolinone synthesis and applications
- Catalytic Processes in Materials Science
- Research on Leishmaniasis Studies
- Covalent Organic Framework Applications
- solar cell performance optimization
- Crystal structures of chemical compounds
- Islamic Studies and History
- Education and Islamic Studies
Kongju National University
2015-2025
University of Bahrain
2021-2025
Karakoram International University
2018-2024
Government College University, Lahore
2024
University College of Bahrain
2021-2024
National College of Business Administration and Economics
2023-2024
University of Engineering and Technology Lahore
2020-2023
Graz University of Technology
2020-2023
Poznań University of Technology
2020-2023
University of the Punjab
2023
The methods like bio-green are advantageous over chemical and physical due to ecofriendly cost-effective synthesis of nanoparticles. Current study was designed for green silver nanoparticles (AgNPs) their biological evaluation. Methanolic extract Bergenia ciliata (BC) rhizomes prepared by maceration used the AgNPs confirmed UV–visible Fourier Transform Infra-Red (FTIR) spectroscopy. Further field emission scanning electron microscope (SEM) shape size determination. In vitro Antioxidant,...
Plant diseases are one of the major threats to global food production. Efficient monitoring and detection plant pathogens instrumental in restricting effectively managing spread disease reducing cost pesticides. Traditional, molecular, serological methods that widely used for often ineffective if not applied during initial stages pathogenesis, when no or very weak symptoms appear. Moreover, they almost useless acquiring spatialized diagnostic results on diseases. On other hand, remote...
Abstract Climate change is a universal issue and plastic trash the major cause of global warming. The present study was specifically designed to address escalating waste problem, biodegradation low-density polyethylene (LDPE) bags investigated over an 8-week period using liquid culture approach. Bacterial strain ( Pseudomonas putida ) capable degrading LDPE isolated from common garbage dumping sites. identified after sequencing analysis, as P. evaluated for its effectiveness in LDPE. Various...
Porcine Pancreatic Elastase (PPE) is a serine protease that homologous to trypsin and chymotrypsin are involved in various pathologies like inflammatory disease, Chronic Obstructive Pulmonary Disease (COPD), acute respiratory distress syndrome, cystic fibrosis, atherosclerosis. PPE if remained uninhibited would lead digestion of important connective tissue. We developed new structurally diverse series adamantyl-iminothiazolidinone hybrids divulge elastase inhibition assay. To identify potent...
A series of novel azomethine precursors were synthesized by the condensation reactions 3-(trifluoromethyl)benzenamine (tfmb) with 2-hydroxybenzaldehyde (HL1) (tfmbs), 2,3-dihydroxybenzaldehyde (HL2) (tfmbdh), 2-hydroxy-1-naphthaldehyde (HL3) (tfmbnd) and 5-chloro-2-hydroxybenzaldehyde (HL4) (tfmbCl). The oxidovanadium(IV) complexes type [VO(tfmbs)2] (1), [VO(tfmbdh)2] (2), [VO(tfmbnd)2] (3) [VO(tfmbCl)2] (4) also prepared reaction ligands HL1–HL4 vanadyl(V) isopropoxide [VO(OCHMe2)3]....
Abstract In the current study, Azo-Thiohydantoins derivatives were synthesized and characterized by using various spectroscopic techniques including FTIR, 1 H-NMR, 13 C-NMR, elemental HRMS analysis. The compounds evaluated for alkaline phosphatase activity it was observed that among all compounds, derivative 7e exhibited substantial inhibitory (IC 50 = 0.308 ± 0.065 µM), surpassing standard inhibitor (L–Phenyl alanine, IC 80.2 1.1 µM). Along with this, these comprehensively examined...
Sulfonamide derivatives serve as an important building blocks in the drug design discovery and development (4D) process. Ciprofloxacin-, sulfadiazine- amantadine-based sulfonamides were synthesized potent inhibitors of jack bean urease free radical scavengers. Molecular diversity was explored electronic factors also examined. All 24 compounds exhibited excellent potential against enzyme. Compound 3e (IC50 = 0.081 ± 0.003 µM), 6a 0.0022 0.0002 9e 0.0250 0.0007 µM) 12d 0.0266 0.0021 found to...
A series of symmetrical salicylaldehyde-bishydrazine azo molecules, 5a-5h, have been synthesized, characterized by 1H-NMR and 13C-NMR, evaluated for their in vitro α-glucosidase α-amylase inhibitory activities. All the synthesized compounds efficiently inhibited both enzymes. Compound 5g was most potent derivative series, powerfully α-amylase. The IC50 against 0.35917 ± 0.0189 µM (standard acarbose = 6.109 0.329 µM), value 0.4379 0.0423 33.178 2.392 µM). Lineweaver-Burk plot indicated that...
Abstract: The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved that compound 6d is a highly potent inhibitor compared to standard kojic acid. title amides 4a–e 6a–e were synthesized following simple reaction routes with excellent yields. Most compounds exhibited good mushroom tyrosinase inhibitory activity, but showed activity (IC 50 0.15 µM) acid 16.69 µM). Lineweaver–Burk plots used...
Abstract Background Pakistan has already encountered intense opposition to polio vaccination due myths and misinformation, now the unfavorable opinions of COVID-19 vaccinations among population would have catastrophic consequences for attempts end pandemic. Methods A web-based cross-sectional study was conducted in general Sindh, January 2021. 31 items based on vaccines availability, safety, myths, questionnaire designed randomly distributed through a google form link. Results were analyzed...
This article empirically assessed new opportunities and provides a conceptual justification for promising areas of trade financial economic relations between China Russia amidst ongoing global turbulence, the post-COVID situation, sanctions pressure. The study utilized gravity model, taking into account latest trends in development research subject object, as well current challenges economy. revealed similarities political systems, reforms, policies Russia, with centralized power structures...
Sodium ion insertion plays a critical role in developing robust sodium-ion technologies (batteries and hybrid supercapacitors). Diffusion coefficient values of sodium (DNa+) tin phosphide between 0.1 V 2.0 vs. Na/Na+ are systematically determined by galvanostatic intermittent titration technique (GITT), electrochemical impedance spectroscopy (EIS), potentiostatic (PITT). These range 4.55 × 10−12 cm2 s−1 1.94 10−8 depend on the insertion/de-insertion current thickness electrode materials....
Human Carbonic Anhydrase inhibitors (CAIs) have been clinically used to treat a variety of disorders, such as cancer, obesity, haemolytic anaemia, glaucoma, retinopathy, and epilepsy. To develop inhibitor, Iminothiazoline analogue ((Z)-N-(3-([1,1'-biphenyl]-2-yl)-4-heptyl-4-hydroxythiazolidin-2-ylidene)-4-bromobenzamide) was synthesized characterized. Single crystal X-Ray diffraction studies Hirshfeld surface analysis (HSA) were conducted find the exact molecular structure well...
The manner in which people apologize differs widely among different cultures because these differences stem from societal pragmatic standards. research investigates within British and American English speaking populations regarding their apology expressions through analysis of "I'm sorry" "My bad." analyzes Brown Levinson’s (1987) theory Politeness Leech’s (2014) principles various social environments. A quantitative design was selected to gauge confirming 200 participants Britain America...
The current research article reports the synthesis of coumarinyl pyrazolinyl thioamide derivatives and their biological activity as inhibitors jack bean urease. thioamides were synthesized by reacting thiosemicarbazide with newly chalcones to afford products in good yields compounds purified recrystallization. Coumarinyl 5a – 5q showed significant against Urease enzyme also exhibited antioxidant potential. compound 3‐(2‐oxo‐2 H ‐chromen‐3‐yl)‐5‐phenyl‐4,5‐dihydro‐1 ‐pyrazole‐1‐carbothioamide...