A5087805349- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- Food Allergy and Anaphylaxis Research
- Platelet Disorders and Treatments
- Respiratory viral infections research
- Respiratory and Cough-Related Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Drug-Induced Adverse Reactions
- Congenital Heart Disease Studies
- Digestive system and related health
- Vitamin D Research Studies
- Enzyme function and inhibition
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Vitamin K Research Studies
- Human Health and Disease
- Neonatal Health and Biochemistry
- Inflammasome and immune disorders
- IL-33, ST2, and ILC Pathways
- Congenital heart defects research
- Tracheal and airway disorders
- Inhalation and Respiratory Drug Delivery
- Mast cells and histamine
- Eating Disorders and Behaviors
Izmir University
2020-2023
University of Health Science
2023
Sağlık Bilimleri Üniversitesi
2022-2023
ENT and Allergy
2023
Institute of Immunology
2023
Dr. Behçet Uz Çocuk Hastalıkları Hastanesi
2020
The purpose of this study was to evaluate patients diagnosed with 22q11.2 deletion syndrome and determine the clues directing diagnosis evaluation immunological findings for excellent management disease.Thirty-three pediatric between 1998 2019 at Pediatric Immunology Division Ege University Faculty Medicine SBU Izmir Dr Behcet Uz Children's Education Research Hospital were evaluated.This includes largest case series reported from Turkey. Congenital cardiac anomalies most common pathology...
It is known that platelets play an important role in inflammatory diseases. Atopic dermatitis (AD) a chronic, itchy, recurrent skin disease affects 2%-30% of the population, especially childhood.We investigated platelet count and mean volume (MPV) as biomarkers children with AD.This cross-sectional retrospective study examined medical reports patients who were referred to Pediatric Allergy Immunology Outpatient Clinic Medical Faculty Hospital, Istanbul Biruni University Diseases Clinics...
Background/aim: The incidence of cat allergies in children has increased over the years. Children with have mostly reported respiratory symptoms. skin prick test (SPT) is most preferred method to demonstrate sensitization allergens. However, not all who develop due environmental exposure become allergic cats. In our study, we aimed determine frequency and allergy, cat-related symptoms, cut-off value for SPT that may indicate allergy. Materials methods: Patients aged 2-18 years, applied...
Objective: In a large group of patients with primary immunodeficiency (PID), immunoglobulin replacement therapy is critical for infection control. There are two main methods intravenous (IVIG) and subcutaneous (SCIG). The aim this study was to determine the efficacy SCIG by comparing IgG levels frequency infections obtained during replacements in PID those IVIG administration. Method: Immunoglobulin 28 who were followed up our clinic diagnosis started switched after follow-up, evaluated...
Acute asthma exacerbations (AAE) are episodes characterized by potentially life-threatening and rapidly deteriorating symptoms. Viral respiratory infections one of the major triggers in pathophysiology childhood exacerbations. In this study, we aimed to determine distribution viral agents among pediatric AAE patients. One hundred three patients, aged 5 or older, hospitalized between from February 2017 through 2020 at Pediatric Immunology Allergic Diseases Unit were included study. Fifty...
Objective: Hereditary Angioedema (HAE) is a rare but life-threatening disease. It aimed to present data on the clinical characteristics of our pediatric patients with HAE, whose symptoms usually start in childhood, delay diagnosis still serious problem. Method: Clinical and laboratory findings, family histories, 14 HAE diagnosed clinic between 1998-2019 were analyzed. Results: Half girls, 78.5% them type 1, 21.4% 2. All had history, 10 based their history. The mean age at was 9.7±4.4 years...
Objective: As a primary immunodeficiency X-linked agammaglobulinemia (XLA) that develops due to Bruton tyrosine kinase signal transduction protein deficiency which progresses with antibody was firstly described by an American pediatrician Ogden Bruton.In our study, we have aimed evaluate the demographic, clinical, immunological, genetic characteristics and follow-up findings of patients diagnosed XLA in tertiary care Pediatric Immunology Clinic.Method: Twelve between 2003-2022 pediatric...
Objective: Atopic dermatitis (AD) is a chronic, itchy, recurrent, and recurrent inflammatory skin disease that affects 2-20% of the population, especially in childhood.Its pathophysiology complex occurs as result genetic, immunological, environmental factors, epithelial-barrier dysfunction.We determined frequency food sensitization vitamin D deficiency patients with AD.Methods: This cross-sectional retrospective study was conducted by examining files who were admitted to pediatrics allergy...
A 4-year-old boy presented with acute-onset autoimmune cytopenia severe, persistent lymphopenia, thyroiditis, elevated IgE and glucose 6-phosphate dehydrogenase enzyme deficiency. In immunologic evaluation, lower T, B natural killer cells higher levels of adenosine deaminase (ADA) metabolites were observed. The compound heterozygous novel ADA gene mutations causing deficiency detected. Successful metabolic cure was achieved replacement therapy, followed by reduced intensity conditioning...
Amaç: Astım, çocukluk çağı kronik hastalıkları arasında en sık görülen ve reversibl hava yolu obstrüksiyonu ile karakterize enflamatuvar bir hastalıktır.Çalışmamızda astım tanısı kesinleştirilen çocukların ilk kez semptomlarının hangi yaşta başladığının
Intravenous immunoglobulin (IVIG), which is primarily G (IgG), used in the treatment of many diseases. While it generally well tolerated, some adverse effects may be seen different systems during IVIG treatment. The infusion are typically mild and related to rate. formation aggregates that lead activation complement system can prevented by decreasing rate, overcome. In rare cases, however, severe life-threatening develop, such as anaphylaxis, cardiac dysrhythmia, bronchospasm, changes...
Objective: Asthma is one of the most common chronic diseases childhood. Many studies have shown that education positively affects asthma control and patients’ quality life. In this study, it was aimed to measure awareness levels children who been under observation for a long time underwent Allergen Specific Immunotherapy (AIT). Methods: Patients with asthma, & allergic rhinitis and/or rhinoconjunctivitis received subcutaneous AIT between July 2019 December were included in our...