- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Immunodeficiency and Autoimmune Disorders
- Respiratory and Cough-Related Research
- Food Allergy and Anaphylaxis Research
- Blood disorders and treatments
- Ocular Surface and Contact Lens
- Platelet Disorders and Treatments
- Olfactory and Sensory Function Studies
- Human Health and Disease
- Respiratory viral infections research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Vaccine Coverage and Hesitancy
- Immune Cell Function and Interaction
- Congenital heart defects research
- Enzyme function and inhibition
- Infant Health and Development
- Neonatal and fetal brain pathology
- Inflammasome and immune disorders
- IL-33, ST2, and ILC Pathways
- Cancer Immunotherapy and Biomarkers
- Infant Development and Preterm Care
- Digestive system and related health
- Bacterial Infections and Vaccines
- COVID-19 Impact on Reproduction
Istanbul Medipol University
2021-2025
Gaziantep Children's Hospital
2022-2024
Biruni University
2022-2024
ENT and Allergy
2023
Sağlık Bilimleri Üniversitesi
2020-2022
Dr. Behçet Uz Çocuk Hastalıkları Hastanesi
2020-2021
Balıkesir University
2021
Izmir University
2020
Objective The benefits of incorporating breathing exercises as an adjunct to medical treatment in the management asthma are well established. Video game-based interventions notable for additional advantages they offer children with chronic respiratory diseases; however, research specifically focusing on remains limited. This study aimed compare effects video and conventional pulmonary extrapulmonary features asthma.
ABSTRACT Objective: Continued progress in our understanding of the food protein–induced allergic proctocolitis (FPIAP) will provide development diagnostic tests and treatments. We aimed to identify precisely clinical features natural course disease a large group patients. Also, we investigated predicting risk factors for persistent since influencing parameters has not yet been established. Methods: Infants who were admitted with rectal bleeding had diagnosis 5 different allergy or...
The purpose of this study was to evaluate patients diagnosed with 22q11.2 deletion syndrome and determine the clues directing diagnosis evaluation immunological findings for excellent management disease.Thirty-three pediatric between 1998 2019 at Pediatric Immunology Division Ege University Faculty Medicine SBU Izmir Dr Behcet Uz Children's Education Research Hospital were evaluated.This includes largest case series reported from Turkey. Congenital cardiac anomalies most common pathology...
It is known that platelets play an important role in inflammatory diseases. Atopic dermatitis (AD) a chronic, itchy, recurrent skin disease affects 2%-30% of the population, especially childhood.We investigated platelet count and mean volume (MPV) as biomarkers children with AD.This cross-sectional retrospective study examined medical reports patients who were referred to Pediatric Allergy Immunology Outpatient Clinic Medical Faculty Hospital, Istanbul Biruni University Diseases Clinics...
Abstract PURPOSE Allergic rhinoconjunctivitis (ARC) is an allergic upper respiratory tract disease characterized by sneezing, runny nose, nasal congestion and ocular itching due to inflammation of the conjunctival mucosa. There are no studies evaluating both choroidal retinal areas in ARC patients. Our objective was evaluate patients with at time diagnosis before initiating treatment using Optical Coherence Tomography (OCT). METHODS This prospective cross-sectional study included 30 who...
Background: Allergic rhinoconjunctivitis (ARC) is an allergic upper respiratory tract disease characterized by sneezing, runny nose, nasal congestion and ocular itching due to inflammation of the conjunctival mucosa. There are no studies evaluating both choroidal retinal areas in ARC patients. Our objective was evaluate patients with at time diagnosis before initiating treatment using Optical Coherence Tomography (OCT). Methods: This prospective cross-sectional study included 30 who...
Purpose: Allergic rhinoconjunctivitis (ARC) is an allergic upper respiratory tract disease characterized by sneezing, runny nose, nasal congestion and ocular itching due to inflammation of the conjunctival mucosa. There are no studies evaluating both choroidal retinal areas in ARC patients. Our objective was evaluate patients with at time diagnosis before initiating treatment using Optical Coherence Tomography (OCT). Material methods: This prospective cross-sectional study included 30 who...
Marmara bölgesinde yaşayan ve atopik yakınmalar ile kliniğimize başvurmuş hastaların aeroalerjen duyarlılıklarının dağılımını incelemek istedik. Çocuk İmmünolojisi Alerji Hastalıkları Polikliniği’ne Nisan 2023-Nisan 2024 tarihleri arasında başvuran 0-18 yaş arası hastalardan deri prickprik test (DPT) uygulanmış olgular geriye dönük olarak değerlendirildi. Olguların % 40,2’ si (n=355) nonsensitize, 46,2’ (n=408) monosensitize, 13,6’ sı (n=120) polisensitize idi. Olgularımızda en sık (% 44,3)...
Objective: In a large group of patients with primary immunodeficiency (PID), immunoglobulin replacement therapy is critical for infection control. There are two main methods intravenous (IVIG) and subcutaneous (SCIG). The aim this study was to determine the efficacy SCIG by comparing IgG levels frequency infections obtained during replacements in PID those IVIG administration. Method: Immunoglobulin 28 who were followed up our clinic diagnosis started switched after follow-up, evaluated...
Background : Febrile seizures are the most common form of convulsive disorder in childhood. The mechanisms underlying pathogenesis febrile seizure remain unclear. Objective: aim this study was to assess immunoglobulin (IG) sub-group levels children with seizures. Methods and Material: patients a diagnosis an age range 1–7 years who attended clinic were included study. Neurologically normal age- sex-matched no history considered as controls. Results: A total 64 100 control subjects...
Acute asthma exacerbations (AAE) are episodes characterized by potentially life-threatening and rapidly deteriorating symptoms. Viral respiratory infections one of the major triggers in pathophysiology childhood exacerbations. In this study, we aimed to determine distribution viral agents among pediatric AAE patients. One hundred three patients, aged 5 or older, hospitalized between from February 2017 through 2020 at Pediatric Immunology Allergic Diseases Unit were included study. Fifty...
Amaç: Bu çalışmamızda 12-18 yaş arası alerjik hastalığı olan bireylerin ebeveynlerindeki aşı kararsızlığı sıklığını ve bunun olası sebeplerini ortaya koymayı amaçladık. Gereç yöntem: Prospektif bu çalışmaya Şubat 2022 - Temmuz tarihleri arasında konjonktivit, rinokonjoktivit, astım, atopik egzema, kronik idiopatik ürtiker besin alerjisi tanılarıyla başvuran hastalar dahil edildi. Toplam 72 çocuk değerlendirildi. Bulgular: Çalışmaya alınan hastaların %36,1’ i (n=26) kız idi. Ortalama 14,2±1,6...
Objective: There have been few studies on prognosis and factors influencing the in children with atopic asthma.We intended to evaluate prognosis, clinical remission rate, of childhood asthma. Methods:In 72 pediatric patients asthma who were followed up between 2016 2022 a mean follow-up period 6.03±2.19years, demographic characteristics, family history, symptoms, pulmonary function test results, control scores evaluated.Totally controlled had not received any treatment for ≥1 year considered...
Objective: Hereditary Angioedema (HAE) is a rare but life-threatening disease. It aimed to present data on the clinical characteristics of our pediatric patients with HAE, whose symptoms usually start in childhood, delay diagnosis still serious problem. Method: Clinical and laboratory findings, family histories, 14 HAE diagnosed clinic between 1998-2019 were analyzed. Results: Half girls, 78.5% them type 1, 21.4% 2. All had history, 10 based their history. The mean age at was 9.7±4.4 years...
Objective: As a primary immunodeficiency X-linked agammaglobulinemia (XLA) that develops due to Bruton tyrosine kinase signal transduction protein deficiency which progresses with antibody was firstly described by an American pediatrician Ogden Bruton.In our study, we have aimed evaluate the demographic, clinical, immunological, genetic characteristics and follow-up findings of patients diagnosed XLA in tertiary care Pediatric Immunology Clinic.Method: Twelve between 2003-2022 pediatric...
Objective: Atopic dermatitis (AD) is a chronic, itchy, recurrent, and recurrent inflammatory skin disease that affects 2-20% of the population, especially in childhood.Its pathophysiology complex occurs as result genetic, immunological, environmental factors, epithelial-barrier dysfunction.We determined frequency food sensitization vitamin D deficiency patients with AD.Methods: This cross-sectional retrospective study was conducted by examining files who were admitted to pediatrics allergy...
Amaç: Astım, çocukluk çağı kronik hastalıkları arasında en sık görülen ve reversibl hava yolu obstrüksiyonu ile karakterize enflamatuvar bir hastalıktır.Çalışmamızda astım tanısı kesinleştirilen çocukların ilk kez semptomlarının hangi yaşta başladığının
Intravenous immunoglobulin (IVIG), which is primarily G (IgG), used in the treatment of many diseases. While it generally well tolerated, some adverse effects may be seen different systems during IVIG treatment. The infusion are typically mild and related to rate. formation aggregates that lead activation complement system can prevented by decreasing rate, overcome. In rare cases, however, severe life-threatening develop, such as anaphylaxis, cardiac dysrhythmia, bronchospasm, changes...