A5022181509- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Eosinophilic Esophagitis
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Epilepsy research and treatment
- Cystic Fibrosis Research Advances
- Immunodeficiency and Autoimmune Disorders
- Inhalation and Respiratory Drug Delivery
- Pharmaceutical studies and practices
- Dermatology and Skin Diseases
- Congenital heart defects research
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Pediatric health and respiratory diseases
- Pharmacological Effects and Toxicity Studies
- Tracheal and airway disorders
- Complementary and Alternative Medicine Studies
- Neonatal Respiratory Health Research
- Diabetes and associated disorders
- Metabolism and Genetic Disorders
- Inflammasome and immune disorders
Karadeniz Technical University
2015-2025
Bursa Uludağ Üni̇versi̇tesi̇
2014
Hacettepe University
2003-2005
Boston Children's Hospital
2004
Abstract: Urticaria is a common disease in children. In contrast to the ease of its diagnosis, etiologic factors are often difficult determine. order study whether differences exist among various forms urticaria childhood and patterns different types differ between adults children, we extensively studied possible causes Fifty‐four children (23 girls 31 boys; ages 1–19 years) with were included study. all cases, questions about food allergies, additive intolerance, drug intake, signs...
Low-Dose MDCT and Virtual Bronchoscopy in Pediatric Patients with Foreign Body AspirationPolat Koşucu1, Ali Ahmetoğlu1, Ismail Koramaz2, Fazil Orhan3, Oğuzhan Özdemir1, Hasan Dinç1, Ayşenur Ökten3 Halit Reşit Gümele1Audio Available | Share
The prevalence of adverse reactions to food in childhood Turkey is not known.We aimed investigate the and characteristics IgE-mediated allergies (FAs) 6-9-year-old urban schoolchildren.This cross-sectional study recruited 3500 randomly selected schoolchildren from eastern Black Sea region during 2006. Following a self-administered questionnaire completed by parents child, consenting children were invited for skin prick tests (SPTs) oral challenges. Children with suspected FA tested...
To evaluate the prognosis of breath holding spells (BHS) after iron treatment, 91 children (56 boys, 35 girls) aged between 6 months and 40 (median, 17) were followed prospectively for a median 45 (range, 6-89). In 49 children, frequency BHS was less than 10 each month, in 22 it 10-30 20 more 30 month. The cyanotic 60 children. All patients evaluated initially during follow up haematological indices. Electroencephalographic electrocardiographic abnormalities also recorded. Sixty three found...
Summary Background Anaphylaxis is a serious and potentially lethal systemic reaction affecting more than one organ or system. Objective We aimed to describe the demographic characteristics, clinical features, causes, settings, administered therapy in T urkish children. Methods This retrospective, case note study included all children referred outpatient clinics of P ediatric A llergy D epartments participating centres from 1 J uly 1999 30 une 2009 for investigation anaphylaxis who were seen...
Abstract Background Genetic deficiencies of immune system, referred to as inborn errors immunity (IEI), serve a valuable model study human responses. In multicenter prospective cohort, we evaluated the outcome SARS‐CoV‐2 infection among IEI subjects and analyzed genetic characteristics that determine adverse COVID‐19 outcomes. Methods We studied 34 patients (19M/15F, 12 [min: 0.6‐max: 43] years) from six centers. diagnosed by finding positive PCR test ( n = 25) and/or lung tomography scoring...
We conducted a study to assess the effect of phenobarbital, carbamazepine, and valproate on serum lipid profiles lipoprotein (a) in 64 children with epilepsy (aged between 1 15 years) admitted child neurology outpatient clinic July 2000 2002. The were separated as group (18 children), treated 5 mg/kg/day; 2 (22 10 3 (24 sodium valproate, 20 mg/kg/day. Plasma (a), total cholesterol, triglycerides, low-density high-density apolipoprotein A B levels, liver enzymes alanine aminotransferase,...
Background Rhinoconjunctivitis (RC) is regarded as the most common chronic disease of childhood; however, currently available epidemiological studies on prevalence, burden, and risk factors RC are insufficient. This analysis aimed to investigate potential factors, symptom frequency, burden RC. Methods Using International Study Asthma Allergies in Childhood Phase II questionnaires, 6963 elementary school children aged 9–11 years were surveyed five different city centers Turkey. All...
Cystic fibrosis (CF) care has been implemented in Turkey for a long time; however, there had no patient registry. For this purpose, the Turkish National CF Registry was established. We present first results of registry using data collected 2017.The were data-entry software system, which accessed from internet. Demographic and annually recorded consisted 15 79 variables, respectively.There 1170 patients registered 23 centers; estimated coverage rate 30%. The median age at diagnosis 1.7 years...
Epidemiologic studies about the prevalence of adverse drug reactions in children are scarce compared to reports adults. To assess parental-reported allergy 6- 9-yr-old urban school children, we performed a cross-sectional study from eastern Black Sea region Turkey during year 2004, using self-administered questionnaire by parents. Response rate was 81.6% (2855/3500). The 2.8% (81/2855). most common drugs were penicillins and other beta-lactams (59.3%), trimethoprim-sulfamethoxazole (11.1%),...
Paired box 1 (PAX1) deficiency has been reported in a small number of patients diagnosed with otofaciocervical syndrome type 2 (OFCS2). We described six new who demonstrated variable clinical penetrance. Reduced transcriptional activity pathogenic variants confirmed partial or complete PAX1 deficiency. Thymic aplasia and hypoplasia were associated impaired T cell immunity. Corrective treatment was required 4/6 patients. Hematopoietic stem transplantation resulted poor immune reconstitution...
The prevalence of allergic diseases such as asthma, hay fever, and atopic dermatitis has increased over the past few decades, especially in developed countries. They are characterized by a chronic inflammatory reaction mediated T helper 2 (Th2) cells. Two common childhood-an autoimmune disease, type 1 diabetes mellitus (DM), viral infection, hepatitis B virus (HBV) carriers-are associated with Th1-dominant Th1-insufficient cytokine profile, respectively. purpose this study was to analyze...
To analyse the epidemiological and clinical features of children with Crimean-Congo haemorrhagic fever (CCHF) in north-eastern Turkey.A retrospective study demographic physical laboratory findings 21 CCHF is described. Clinical course, treatment modalities outcome were analysed.Most patients admitted June July 2008; most from Gumushane Kelkit valleys half them lived rural areas. Mean (SD) age was 10.3 (3.9) years disease more common males (71.4%). Approximately 70% had a history tick bite....
Abstract Background Accumulating evidence suggests, asthma includes many phenotypes with varying clinical and prognostic features. Epidemiological surveys documented a number of environmental risk factors for the development interestingly these differ between within countries, suggesting that differences may be related different distribution phenotypes. This study aimed to investigate current wheezing (CW) in elementary school children. Methods Six thousand nine hundred sixty‐three 9‐...
ABSTRACT Objective: Continued progress in our understanding of the food protein–induced allergic proctocolitis (FPIAP) will provide development diagnostic tests and treatments. We aimed to identify precisely clinical features natural course disease a large group patients. Also, we investigated predicting risk factors for persistent since influencing parameters has not yet been established. Methods: Infants who were admitted with rectal bleeding had diagnosis 5 different allergy or...
Immunoglobulin G replacement therapy (IgRT), intravenous (IV) and subcutaneous (SC) routes, is pivotal in treatment of primary immunodeficiencies (PID). In recent years, facilitated immunoglobulin (fSCIG), a combination rHuPH20 10% IgG has emerged as delivery method to combine advantages both IV SC.