- Breast Cancer Treatment Studies
- Heart Failure Treatment and Management
- Lung Cancer Treatments and Mutations
- Atrial Fibrillation Management and Outcomes
- Cancer Treatment and Pharmacology
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- HER2/EGFR in Cancer Research
- Lung Cancer Research Studies
- Breast Lesions and Carcinomas
- Gastric Cancer Management and Outcomes
- Cancer Immunotherapy and Biomarkers
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Pancreatic and Hepatic Oncology Research
- Pharmaceutical Practices and Patient Outcomes
- Diabetes Treatment and Management
- Cardiac Arrhythmias and Treatments
- Aortic Disease and Treatment Approaches
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Advanced Breast Cancer Therapies
Trakya University
2010-2025
UPMC Presbyterian
2022-2024
Konya Eğitim ve Araştırma Hastanesi
2024
Cukurova University
2023-2024
University of Pittsburgh Medical Center
2019-2024
Shadyside Hospital
2022-2024
Başkent University
2021-2023
UPMC Health System
2023
Adana Hospital
2023
University of Health Science
2023
Lazertinib is a potent, CNS-penetrant, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. This global, phase III study (LASER301) compared lazertinib versus gefitinib in treatment-naïve patients with EGFR-mutated (exon 19 deletion [ex19del]/L858R) locally advanced or metastatic non-small-cell lung cancer (NSCLC).Patients were 18 years and older no previous systemic anticancer therapy. Neurologically stable CNS metastases allowed. Patients randomly assigned...
We aimed to evaluate retrospectively the correlation of loco-regional relapse (LRR) rate, distant metastasis (DM) disease free survival (DFS) and overall (OS) in a group breast cancer (BC) patients who are at intermediate risk for LRR (T1-2 tumor 1-3 positive axillary nodes) treated with or without postmastectomy radiotherapy (PMRT) following modified radical mastectomy (MRM).Ninety patients, T1-T2 tumor, nodes had undergone MRM received adjuvant systemic therapy (n = 66) 24) PMRT....
Reoperative sternotomy is associated with poor outcomes after cardiac surgery. We aimed to investigate the impact of reoperative on aortic root replacement.
Catheter-directed thrombolysis (CDL) is increasingly being used for the treatment of submassive and massive pulmonary embolism. Although this therapy has been shown to be effective at reducing right ventricle strain, impact on clinical outcomes remains unclear. We therefore aimed evaluate CDL compared standard anticoagulation embolism patients in a large cohort.
Introduction:We report the primary analysis from JAVELIN Lung 100, a phase 3 trial comparing avelumab (anti -PD-L1) vs platinum-based doublet chemotherapy as first-line treatment for PD-L1+ advanced non-small cell lung cancer (NSCLC).Methods: Adults with (≥1% of tumor cells; PD-L1 IHC 73-10 pharmDx), EGFR/ALK-wild-type, previously untreated, stage IV NSCLC were randomized to 10 mg/kg every 2 weeks (Q2W), once weekly (QW) 12 and Q2W thereafter, or weeks.Primary endpoints overall survival (OS)...
Osteoporosis is a silent disease because individuals may not know that they have osteoporosis until their bones become so fragile. Bone mineral density (BMD) test helps to detect and determine the risk fractures. This study covers bone measurement data from total body dual energy X-ray absorptiometry scans for 28,454 persons who participated in 1996-2006 National Health Nutrition Examination Survey USA Dual (DXA) method known as primary detecting of its high precision accuracy. Testing...
Preclinical evaluation of bintrafusp alfa (BA) combined with radiotherapy revealed greater antitumor effects than BA or alone. In a phase 1 study, exhibited encouraging clinical activity in patients stage IIIB IV NSCLC who had received previous treatment.
PURPOSE Breast cancer is the most frequent in women, and there a great variability surgical practice for treating that different countries. The aims of this study were to analyze effect guidelines from Turkish Federation Diseases Societies on academic institutions have breast centers evaluate Turkey 2018. PATIENTS AND METHODS Between January March 2019, survey was sent surgeons who working institutions. sampling frame included 24 with 18 cities interdisciplinary differences among seven...
Background Over the next few years, atrial fibrillation (AF)-related morbidity and costs will increase significantly. Thus, it is prudent to examine impact of AF treatment on health care resource use. This study examined ablation hospitalization, length stay, use for patients undergoing in a multihospital system. Methods Results In an observational analysis, outcomes total, cardiovascular, hospitalizations, emergency department visits, stay were compared 3417 between 12 months before 24...