- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Global Cancer Incidence and Screening
- Breast Implant and Reconstruction
- Cancer Risks and Factors
- BRCA gene mutations in cancer
- Cancer Treatment and Pharmacology
- Cancer survivorship and care
- HER2/EGFR in Cancer Research
- Cancer Immunotherapy and Biomarkers
- Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Cancer Cells and Metastasis
- Advanced Breast Cancer Therapies
- Economic and Financial Impacts of Cancer
- AI in cancer detection
- Cancer and Skin Lesions
- Estrogen and related hormone effects
- Cervical Cancer and HPV Research
- Colorectal Cancer Screening and Detection
- Digital Radiography and Breast Imaging
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Lymphatic System and Diseases
- Nutrition, Genetics, and Disease
Istanbul University
2016-2025
Istanbul Florence Nightingale Hospital
2014-2025
Breast Center
2014-2025
Nightingale Hospital
2016-2024
Nutrition 21 (United States)
2024
Istanbul Bilim University
2016-2022
Liv Hospital
2017-2022
Cukurova University
2016-2020
Sağlık Bilimleri Üniversitesi
2020
Izmir University
2020
Granulomatous mastitis (GM) is a rare inflammatory breast disease of unknown etiology. Although it usually presents with sinus formation and abscesses, may mimic the clinical characteristics cancer. The aim this study was to identify clinical, radiologic, pathologic patients GM show results surgical treatment in these patients. A chart review performed for that were treated diagnosis at Breast Unit, Department Surgery, Istanbul Medical Faculty, University Istanbul, between September 1998...
Background: Reducing treatment delay improves outcomes in breast cancer. The aim of this study was to determine factors influencing patient- and system-related delays commencing cancer different countries. Methods: A total 6588 female patients from 12 countries were surveyed. Total time determined as the sum patient-related (time between onset first symptoms medical visit) visit start therapy). Results: average 4.7 (range: 3.4–6.2) weeks 14.4 11.5–29.4) weeks, respectively. Longer times...
Introduction: Secondary lymphedema is one of the major important long-term complications breast cancer treatment. The aim this study to determine patient- and treatment-related risk factors in patients. Patients Methods: Patients, who had been operated on for primary at Akdeniz University Hospital followed regularly between August 1984 December 2009 were included study. In order evaluate arm swelling objectively, measurements performed with a flexible tape measure both arms, limb volume was...
Hereditary cancer predisposition syndromes are responsible for approximately 5-10% of all diagnosed cases. In the past, single-gene analysis specific high risk genes was used determination genetic cause heritability in certain families. The application Next Generation Sequencing (NGS) technology has facilitated multigene panel and is widely clinical practice, identification individuals with predisposing gene variants. purpose this study to investigate extent nature variants implicated...
Breast cancer is the most common type of and leading cause cancer-related deaths in women Turkey. This study presents characteristics patients registered National Cancer Registry Program Turkish Federation Diseases Societies.The registry contains 242 variables under 10 categories 699 questions. Patients were recorded (online offline) from nationwide breast centers around Turkey.Twenty-thousand between May 2005 April 2017 at 36 centers. After data cleaning, 19,503 included study. The median...
Abstract Objectives We aimed to evaluate the early-detection capabilities of AI in a screening program over its duration, with specific focus on detection interval cancers, early cancers assistance from prior visits, and impact workload for various reading scenarios. Materials methods The study included 22,621 mammograms 8825 women within 10-year biennial two-reader program. statistical analysis focused 5136 4282 due data retrieval issues, among whom 105 were diagnosed breast cancer....
Importance Increasing evidence supports the oncologic safety of de-escalating axillary surgery for patients with breast cancer after neoadjuvant chemotherapy (NAC). Objective To evaluate outcomes among clinically node (cN)–positive and whose disease became cN negative NAC (ycN negative). Design, Setting, Participants In NEOSENTITURK MF-1803 prospective cohort registry trial, from 37 centers cT1-4N1-3M0 treated sentinel lymph biopsy (SLNB) or targeted dissection (TAD) alone ypN-negative...
Breast cancer has been increased in developing countries, but there are limited data for breast risk factors these countries. To clarify the among Turkish women, an university hospital based nested case-control study was conducted. Between January 2000 and December 2006, a survey prospectively conducted women admitted to clinics of Istanbul Medical Faculty examination and/or treatment by using questionnaire. Therefore, characteristics patients diagnosed with (n = 1492) were compared control...
In 2002 the Breast Health Global Initiative (BHGI) convened a panel of breast cancer experts and patient advocates to develop consensus recommendations for diagnosing in countries with limited resources. The agreed on need pathologic diagnosis, based microscopic evaluation tissue specimens, before initiating treatment. discussed options diagnosis (fine-needle aspiration biopsy, core needle surgical biopsy) concluded that choice among these methods should be available tools expertise....
Single-incision videoendoscopic surgery has recently become popular as a result of the ongoing search for less invasive procedures. The aim this study was to evaluate safety and efficacy endoscopic single-port nipple-sparing mastectomy, axillary lymphadenectomy, immediate reconstruction in patients with breast cancer.From May 14, 2012 through January 23, 2013, 10 underwent mastectomy dissection via single, limited incision prosthetic reconstruction. Patient charts were reviewed, demographic...
Objective: Breast cancer is the most common type of and leading cause related deaths in women Turkey, as elsewhere around world.However, detailed systematic demographics, data on clinical pathological characteristics, treatment were largely unavailable Turkey until now.This paper intended to provide an analysis registered National Cancer Database (Ulusal Meme Kanseri Veri Tabanı [UMKVT]), established within Turkish Federation Diseases Societies (TMHDF) available for use since 2005. Materials...
The correlation between imaging findings and pathologic characteristics of tumors may provide information for diagnosis treatment cancer. aim this study is to determine whether ultrasound features breast cancer are associated with molecular subtype, histologic grade, hormone receptor status, as well assess the predictive value these features.A total 201 consecutive invasive patients were reviewed from database according Breast Imaging Reporting Data System (BI-RADS). Tumor margins classified...
1005 Background: The MF07-01 trial is a multicenter phase III randomized of treatment naive stage IV BC patients comparing loco-regional surgery (LRS) followed by appropriate systemic therapy (ST) vs ST alone. Aims: To compare 3-year survival and progression (LRP). Methods: At initial diagnosis were 1:1 to LRS group or group. After consideration retrospective studies, we hypothesized at 36 months difference between the two groups be 18%. Assuming 10% drop out rate with one sided log-rank...
Purpose: To evaluate the performance of an artificial intelligence (AI) algorithm in a simulated screening setting and its effectiveness detecting missed interval cancers. Methods: Digital mammograms were collected from Bahcesehir Mammographic Screening Program which is first organized, population-based, 10-year (2009-2019) program Turkey. In total, 211 extracted archive this retrospective study. One hundred ten them diagnosed as breast cancer (74 screen-detected, 27 interval, 9 missed), 101...
Lymphedema, a sequela of breast cancer and therapy, changes functional abilities may affect patient's psychosocial adjustment overall quality life. Aim this prospective observational study was to determine the rate mid-term late time period lymphedema in patients with different loco-regional treatments, factors associated lymphedema.Patients surgically treated for early-stage were prospectively enrolled study. Demographic, clinical, pathological, treatments data rates recorded. Patients...
The aim of this study was to investigate the impacts personality traits, anxiety, depression and hopelessness levels on quality life in patients with breast cancer.The performed 90 diagnosed cancer healthy women. Sociodemographic Clinical Data Collection Form designed by us, Beck Hopelessness Scale (BHS), Anxiety (BAS), Depression (BDS), Eysenck Personality Inventory (EPI) Quality Life Scale-Short (SF-36) were administered control group.The found indicate higher anxiety depression, lower...
Background: One of the most important factors in breast cancer (BC) mortality is treatment delay. The primary goal this survey was to identify affecting total delay time (TDT) Turkish BC patients. Methods: A 1031 patients with were surveyed using a uniform questionnaire. between discovering first symptom and signing up for medical visit (patient time; PDT) start therapy (system SDT) modelled separately multilevel regression. Results: mean PDT, SDT TDT 4.8, 10.5 13.8 weeks, respectively. In...