Alper Akçan

ORCID: 0000-0001-9469-4274
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About
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Research Areas
  • Breast Lesions and Carcinomas
  • Breast Cancer Treatment Studies
  • Cancer and Skin Lesions
  • Metastasis and carcinoma case studies
  • Adrenal and Paraganglionic Tumors
  • Parathyroid Disorders and Treatments
  • Breast Implant and Reconstruction
  • Abdominal vascular conditions and treatments
  • Pituitary Gland Disorders and Treatments
  • Abdominal Surgery and Complications
  • Appendicitis Diagnosis and Management
  • Hernia repair and management
  • Parasitic infections in humans and animals
  • Congenital Anomalies and Fetal Surgery
  • Thyroid Cancer Diagnosis and Treatment
  • Anorectal Disease Treatments and Outcomes
  • Neuropeptides and Animal Physiology
  • Liver Disease and Transplantation
  • Neuroblastoma Research and Treatments
  • Liver physiology and pathology
  • Pancreatic and Hepatic Oncology Research
  • Intestinal and Peritoneal Adhesions
  • Colorectal and Anal Carcinomas
  • Salivary Gland Tumors Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations

Erciyes University
2014-2025

Erciyes Üniversitesi Tıp Fakültesi Hastaneleri
2005-2024

Bozok Universitesi
2020

Kayser (Italy)
2013

Juntendo University Urayasu Hospital
2008

Kanazawa Medical University
2008

Importance Increasing evidence supports the oncologic safety of de-escalating axillary surgery for patients with breast cancer after neoadjuvant chemotherapy (NAC). Objective To evaluate outcomes among clinically node (cN)–positive and whose disease became cN negative NAC (ycN negative). Design, Setting, Participants In NEOSENTITURK MF-1803 prospective cohort registry trial, from 37 centers cT1-4N1-3M0 treated sentinel lymph biopsy (SLNB) or targeted dissection (TAD) alone ypN-negative...

10.1001/jamasurg.2024.5913 article EN JAMA Surgery 2025-01-02

Purpose: To evaluate the radiological, ultrasonographic, and magnetic resonance imaging (MRI) findings of idiopathic granulomatous mastitis. Material Methods: Between April 2002 June 2005, mammography, ultrasound, color Doppler nonenhanced MR, dynamic MR nine patients with preliminary clinical diagnosis malignancy final mastitis were evaluated. Results: On asymmetrical focal densities no distinct margins, ill-defined masses spiculated contours, bilateral multiple nodules seen. in four a...

10.1080/02841850601128975 article EN Acta Radiologica 2007-03-01

Idiopathic granulomatous mastitis (IGM) is an uncommon chronic inflammatory disease of the breast with uncertain optimal treatment regimen. In this study, our purpose was to report clinical experience 74 IGM patients who were treated wide local excision or without steroid therapy.74 cases diagnosed histologically as identified from surgical and pathological records between January 1995 2012. Group 1 (surgery-only group) comprised 53 patients, 21 in group 2 corticosteroids prior...

10.1159/000360926 article EN Breast Care 2014-01-01

To evaluate the predisposing factors for peritoneal perforation and intrabiliary rupture effects of these complications on surgical outcome in liver hydatid disease.A total 372 patients with cysts who had undergone treatment were evaluated retrospectively. Twenty eight perforation, 93 spontaneous 251 noncomplicated treated our clinics.When evaluated, younger age, superficial position, larger cyst dimensions (P < 0.05; range, 0.001-0.017) increased rates. It was shown that older age...

10.3748/wjg.v16.i24.3040 article EN cc-by-nc World Journal of Gastroenterology 2010-01-01

Objective: The second consensus study on idiopathic granulomatous mastitis (IGM) aimed to establish treatment options based the clinical classification proposed in first consensus, standardize criteria for discontinuation, and develop follow-up protocols. Method: A structured methodology, identical study, was employed. An 11-member working group of breast surgeons experienced IGM from various clinics across country formed. modified Delphi method used, with a threshold 80% agreement. Results:...

10.1159/000544967 article EN Breast Care 2025-03-03

To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model.Rats were randomly assigned to three groups: group I: control, II: experimental colitis, III: plus treatment. On d 11 after plasma tumor necrosis factor-alpha, portal blood endotoxin levels, colon tissue myeloperoxidase caspase-3 activity measured. Bacterial was quantified by blood, lymph node, liver spleen culture.We observed significantly reduced incidence liver,...

10.3748/wjg.14.918 article EN World Journal of Gastroenterology 2008-01-01

To investigate the effects of bombesin (BBS) and neurotensin (NTS) on apoptosis colitis in an ulcerative model.In this study, a total 50 rats were divided equally into 5 groups. In control group, no induction or drug administration was performed. Colitis induced all other Following colitis, BBS, NTS both applied to three groups rats. The remaining group (colitis group) received treatment. On 11th d after treatment, blood samples collected for TNF-alpha IL-6 level studies. Malondialdehyde...

10.3748/wjg.14.1222 article EN cc-by-nc World Journal of Gastroenterology 2008-01-01

The aim of this study was to compare the surgical outcome fasciocutaneous V-Y advancement flap and limberg transposition used treat recurrent sacrococcygeal PSD.A total 58 patients with pilonidal sinus who underwent surgery were evaluated retrospectively between January 2008 December 2013. Fasciocutaneous performed in 25 (Group VYF), repair 33 LTF). Patient demographics, operative postoperative outcomes recorded then analyzed.The mean age (p = 0.69), sex ratio 0.48), concomitant diseases...

10.1016/j.asjsur.2015.10.002 article EN cc-by-nc-nd Asian Journal of Surgery 2015-11-25

The differential diagnosis in acute mesenteric ischaemia (AMI) is essential and sometimes life-saving. A marker for early lacking. Citrulline an amino acid mainly synthesized by small bowel enterocytes from glutamine. In this study, we aimed to evaluate the diagnostic prognostic values of citrulline with those D-dimer patients AMI.The were divided into two groups; group 1: abdominal findings which attributed preoperatively AMI, 2: causes other than AMI. All underwent surgical exploration....

10.1111/ans.13524 article EN ANZ Journal of Surgery 2016-04-08

The aim of the present study was to investigate association between non sentinel lymph node metastasis (NSLNM) and clinicopathological factors, particularly in case (SLN) one or two, clinically negative patients with breast cancer.Between 10/2010 10/2014, 350 biopsy (SLNB) were performed histologically proven primary cancer our clinic. data collection includes following characteristics: age, pathological tumor size, histological type, grade, lymphovascular invasion (LVI), number positive...

10.1016/j.asjsur.2016.06.001 article EN cc-by-nc-nd Asian Journal of Surgery 2016-09-09

Laparoscopic adrenalectomy (LA) is a safe and minimally invasive operation for benign adrenal tumours. The purpose of this study was retrospective analysis outcomes following laparoscopic lateral transabdominal performed tumours responsible various endocrinological disorders non-functioning tumours.A total 100 were carried out between January 2007 March 2013 via the approach. analysed factors included demographic data patients, indication surgery, tumour size side, intraoperative...

10.1016/j.asjsur.2015.04.009 article EN cc-by-nc-nd Asian Journal of Surgery 2015-07-11

Multiple breast cancers may present with different clinical and biological characteristics. The data indicate that multifocal (MF), multicentric (MC), bilateral synchronous (BS) (BC) are more aggressive have an equivalent or moderately poorer survival rate compared unilateral cases. However, a comparison of these multiple has not been covered in the literature. aim this study was to describe histopathological characteristics patients suffering from MF, MC, BS carcinoma compare their...

10.1186/1477-7819-12-266 article EN cc-by World Journal of Surgical Oncology 2014-01-01

The most common complication after thyroid surgery is hypocalcaemia and it sometimes leads to problems that are difficult correct in patients. present study was aimed determine the risk factors causing development of surgery.818 adult patients were included study. data recorded by examining hospital automation system patient files retrospectively. Patients' demographic characteristics, radiological imaging findings, serum biochemical parameters, extent performed surgery, histopathological...

10.1016/j.asjsur.2018.12.009 article EN cc-by-nc-nd Asian Journal of Surgery 2019-01-25

Abstract Background: Previous prospective studies reported decreased false negative rates in patients presenting with T1-3/cN1 disease, the removal of 2 or more sentinel lymph nodes (SLNs), using combined technique for SLN biopsy (SLNB), and by targeted axillary dissection (TAD) initially clinically node-positive after neoadjuvant chemotherapy (NAC). The aim this study is to compare feasibility oncological safety TAD SLNB cN-positive/ycN0 breast cancer following NAC a study. Methods: This...

10.1158/1538-7445.sabcs23-ps01-01 article EN Cancer Research 2024-05-02

Objective: The aim of the idiopathic granulomatous mastitis (IGM) consensus study was to evaluate etiology, diagnostic steps, and differential diagnosis propose a widely accepted clinical classification this mysterious breast disease. Method: organization national IGM decided by joint evaluation Turkish Federation Breast Diseases Societies, SENATURK, Society Surgery. First, working group 11 members formed, survey workshop were organized reach common consensus. modified Delphi method used in...

10.1159/000541482 article EN Breast Care 2024-09-18
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