A5048958157- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Thyroid and Parathyroid Surgery
- Parathyroid Disorders and Treatments
- Breast Implant and Reconstruction
- Genetic Syndromes and Imprinting
- Neuroendocrine Tumor Research Advances
- Thyroid Cancer Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Bariatric Surgery and Outcomes
- Cancer and Skin Lesions
- Advanced Breast Cancer Therapies
- Medical Imaging and Pathology Studies
- Body Contouring and Surgery
- Airway Management and Intubation Techniques
- Cancer-related Molecular Pathways
- Medical Imaging Techniques and Applications
- Abdominal Surgery and Complications
- Intestinal and Peritoneal Adhesions
- Pancreatitis Pathology and Treatment
- Cancer Diagnosis and Treatment
- Coding theory and cryptography
- Hernia repair and management
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
Bezmiâlem Vakıf Üniversitesi
2016-2025
Bezmialem Foundation University Medical Faculty Hospital
2009-2013
Istanbul University-Cerrahpaşa
2003-2009
Istanbul University
2005-2009
Importance Increasing evidence supports the oncologic safety of de-escalating axillary surgery for patients with breast cancer after neoadjuvant chemotherapy (NAC). Objective To evaluate outcomes among clinically node (cN)–positive and whose disease became cN negative NAC (ycN negative). Design, Setting, Participants In NEOSENTITURK MF-1803 prospective cohort registry trial, from 37 centers cT1-4N1-3M0 treated sentinel lymph biopsy (SLNB) or targeted dissection (TAD) alone ypN-negative...
Purpose Oxidant/antioxidant balance has been suggested as an important factor for initiation and progression of cancer. The objective this study was to determine 8-hydroxydeoxyguanosine (8-OHdG) level a marker oxidative DNA damage, glutathione peroxidase (G-Px), superoxide dismutase (SOD) activities antioxidant activity, in sera from women with breast Methods Forty-nine patients malign tumor were included the study. Blood samples collected before surgical operation. Serum 8-OHdG measured...
Abstract Background Permanent hypoparathyroidism is a serious problem and requires medications indefinitely. Parathyroid allotransplantation ( PA ) with short‐term immunosuppression definitive choice but long‐term results are not clear. Method We performed from two donors to recipients. Both recipients were 39‐year‐old females. Donors 32‐year‐old female 36‐year‐old male, who both have chronic kidney disease. Routine tests, viral markers, cross‐matches analyzed individually. The parathyroid...
Abstract Background We aimed to minimalize operative complications by spraying of methylene blue stain on thyroid glands and the perithyroidal area. Material methods The intra-operative technique was used prospectively a total 56 patients who had undergone primary (not recurrent) surgery for variety diseases. Bilateral thyroidectomy performed in all cases. After superior but before inferior pole ligation, 0.5ml sprayed over lobe perilober Tissues, especially parathyroides, recurrent...
Abstract Permanent hypoparathyroidism is a severe clinical condition accompanied by low parathyroid hormone level. Conventional treatment requires lifelong medication, and daily drug usage has some side effects. To avoid this circumstance, transplantation an alternative curative option. Microencapsulation may be used as approach particularly to evade immune response. In order define of permanent hypoparathyroidism, 37‐year‐old female recipient who was evaluated for 3 years. Routine tests,...
Background and aims: Because of their rarity late diagnosis, gastro-intestinal bezoars can be treated after the occurrence some complications such as acute intestinal obstruction, strangulation, decubitus ulceration bleeding. In this study, reasons for bezoar formation, measures to taken treatment modalities were investigated. Patients methods: The files patients who found have at Istanbul University, Cerrahpasa Medical Faculty General Surgery Department Emergency Unit between years 1970...
To evaluate the predictive effect of IMA in incarcerated hernias. Three groups (n = 7) rats were operated. Group I aimed to mimic incarceration, group II strangulation, and III was sham group. LDH measurements made. levels significantly higher strangulation mimicking normal at postoperative 6th hour incarceration both groups. seems be an effective marker hernias predict necrosis. But we need further studies generalise this hypothesis.
<h3>Background:</h3> Liver hydatidosis may lead to serious morbidity due biliary complications, the management for which endoscopic sphincterotomy (ES) and drainage are very efficient. We evaluated effectiveness of treatment complications hepatic hydatid disease. <h3>Methods:</h3> retrospectively reviewed retrograde cholangiopancreatography (ERCP) procedures performed between January 2000 December 2009 compared laboratory findings, localization lesions ERCP applied patients with without...
Abstract Background: Previous prospective studies reported decreased false negative rates in patients presenting with T1-3/cN1 disease, the removal of 2 or more sentinel lymph nodes (SLNs), using combined technique for SLN biopsy (SLNB), and by targeted axillary dissection (TAD) initially clinically node-positive after neoadjuvant chemotherapy (NAC). The aim this study is to compare feasibility oncological safety TAD SLNB cN-positive/ycN0 breast cancer following NAC a study. Methods: This...
Abstract Objective We aimed to evaluate cardiac safety profile of ribociclib with 24-h rhythm Holter ECG. Material and method Forty-two female metastatic breast cancer patients were included in the study. Rhythm ECG was performed before starting treatment after 3 months initiation. Results The mean age 56.36 ± 12.73. 52.4% ( n = 22) using combination fulvestrant 47.6% 20) aromatase inhibitors. None developed cardiotoxicity. When results third month compared, there no statistically...
Abstract Background The omission of axillary lymph node dissection (ALND) remains controversial for patients with residual disease after neoadjuvant chemotherapy (NAC), regardless the burden. This study evaluated oncologic safety and factors associated outcomes in disease. These were treated solely sentinel biopsy (SLNB) or targeted (TAD), without ALND, NAC. Methods A joint analysis two different multicenter cohorts—the retrospective cohort registry MF18‐02 prospective observational MF18‐03...
Mondor's disease (MD) of the breast is a rare condition at clinics. We do not have enough data to establish its real prevalence. As known data, most patients that were admitted clinics are cancer. Also MD entity and diagnosing this informing patient about it very important. present here case remind clinic practitioners can be seen without trauma (neither surgical nor physical). clinical radiological findings treatmentof discussed. A 35 year old woman was our with cutaneous retraction. She...
Reconstruction of large abdominal wall defects is a challenging problem. Various reconstructive techniques have been described in the surgical literature each with its advantages and disadvantages. In this report we describe our experience treating patient defect by staged reconstruction utilizing prosthetic mesh conjunction tissue expanders. A 41-year-old male presented pain. Exploratory laparotomy showed perforated appendicitis intraabdominal abscess 1,500 mL. Postoperatively, he developed...
Papillary lesions have a broad spectrum of appearances on magnetic resonance imaging (MRI). The purpose this study was to evaluate whether apparent diffusion coefficient (ADC) values papillary can be used characterize lesion as benign or malignant. This retrospective included 29 lesions. Diagnostic dynamic contrast-enhanced MRI (DCE-MRI), DWI-ADC, and DCE-MRI plus DWI-ADC were separately calculated. malignant (0.744×10-3 mm2 /s) exhibited significantly lower mean ADC than the (1.339×10-3...
Bleeding is a rare and dangerous complication of thyroid surgery. One the hemostatic agents used during surgery are microporous polysaccharide hemospheres (MPH) which local acquired from purified potato starch. The aim this study was to evaluate efficiency two MPH, produced with different biotechniques, in decreasing hemorrhages drainage following thyroidectomy.A statistical power analysis predicted that totally 20 patients per each group needed within 95% confidential interval. Patients...
Permanent hypoparathyroidism is an endocrine disease that mostly associated with the disruption of parathyroid glands during surgery. Allotransplantation most promising approach for treatment particularly its cost-effective and exact curative potential. Herein our aim was to evaluate human leukocyte antigen (HLA)-A allele matching effect on clinical improvement graft survival after transplantation. We performed transplantation between ABO/Rh compatible recipient unrelated donor who has...
Objective To compare urinary iodine excretion levels in patients with breast cancer and control subjects. Methods In this prospective pilot study, normal controls were recruited. Age menopausal status recorded. Levels of serum thyroid-stimulating hormone, blood urea nitrogen creatinine urine concentration (UIC) measured. UIC divided into three categories: low (<100 µg/l), (100–200 µg/l) or high (>200 µg/l). Results A total 24 48 included the study. There no statistically significant...