A5009784421- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Inflammatory Biomarkers in Disease Prognosis
- Pancreatitis Pathology and Treatment
- Breast Implant and Reconstruction
- Appendicitis Diagnosis and Management
- Intraperitoneal and Appendiceal Malignancies
- Cancer Treatment and Pharmacology
- Gastrointestinal disorders and treatments
- Advanced Breast Cancer Therapies
- Helicobacter pylori-related gastroenterology studies
- Sepsis Diagnosis and Treatment
- Hernia repair and management
- BRCA gene mutations in cancer
- Metastasis and carcinoma case studies
- Thyroid Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Cancer and Skin Lesions
- Endometriosis Research and Treatment
- Congenital Anomalies and Fetal Surgery
- Cancer Genomics and Diagnostics
- Mechanisms of cancer metastasis
- Medical Imaging Techniques and Applications
- Ovarian cancer diagnosis and treatment
- Cancer Mechanisms and Therapy
Bursa Uludağ Üni̇versi̇tesi̇
2018-2025
Cancer Clinic
2024
Magee-Womens Hospital
2024
University of Pittsburgh Medical Center
2024
Bursa Technical University
2015-2019
Koç University
2018-2019
Okan University
2018-2019
Ankara Numune Eğitim ve Araştırma Hastanesi
2013-2016
Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi
2015
Abstract Blood-based biomarkers reflect systemic inflammation status and have prognostic predictive value in solid malignancies. As a recently defined biomarker, Pan-Immune-Inflammation-Value (PIV) integrates different peripheral blood cell subpopulations. This retrospective study of collected data aimed to assess whether PIV may predict the pathological complete response (pCR) neoadjuvant chemotherapy (NAC) Turkish women with breast cancer. The consisted 743 patients cancer who were...
Importance Increasing evidence supports the oncologic safety of de-escalating axillary surgery for patients with breast cancer after neoadjuvant chemotherapy (NAC). Objective To evaluate outcomes among clinically node (cN)–positive and whose disease became cN negative NAC (ycN negative). Design, Setting, Participants In NEOSENTITURK MF-1803 prospective cohort registry trial, from 37 centers cT1-4N1-3M0 treated sentinel lymph biopsy (SLNB) or targeted dissection (TAD) alone ypN-negative...
Idiopathic granulomatous mastitis (IGM) is an immune-mediated inflammatory breast disease presenting significant treatment challenges due to its varied symptoms and lack of standardized guidelines. This study aims evaluate the efficacy safety immunosuppressive modalities, including corticosteroids (CS) agents such as methotrexate (MTX) azathioprine (AZA), in managing IGM, with a focus on recurrence rates outcomes. We conducted retrospective analysis 505 female patients diagnosed IGM at Bursa...
To evaluate association between duodenogastric reflux and early gastric mucosal changes before after the cholecystectomy procedure.Patients were evaluated with preoperative postoperative endoscopy endoscopic biopsy. Demographic clinical characteristics, histological parameters, presence of reflux, Updated Sydney scores noted.A total fifty patients who obeyed follow-up enrolled into study. Median age was 43 years (range 25-84). Male-female ratio 0.51 (17/33). Duodenogastric % 24 (48%) versus...
Objective: Acute mesenteric ischemia (AMI) is an infrequent, but complicated, life-threatening condition. Given this poor outcome, estimation of mortality would aid in decision making for physicians, patients and their families. Red cell distribution width (RDW) reflective systemic inflammation. RDW a remarkable prognostic marker determining the risk wide range clinical manifestations. The objective study was to investigate association between with AMI. Methods: medical records who underwent...
In the present study we aimed to figure out effect of metformin on expression AMPK-alpha, cyclin D1, and Tp53, apoptosis in primary breast cancer cells (PBCCs).PBCCs were treated with two doses (0 mM, 25 mM). Proliferation was determined by BrdU as- say. Real-time PCR used assess Tp53 gene expressions; apoptotic indexes PBCCs analyzed using flow-cytometry.Twenty-four–hour incubation mM reduced proliferation PBCCs. AMPK-alpha not affected treatment compared control group. had lower D1...
Metastasis of renal cell carcinoma is seen in approximately 25% all cases. Rarely, they can appear unusual sites. Herein, we present a 40-year-old female patient with an itching scalp mass. The mass appeared one year after the nephrectomy performed for right carcinoma. Computed tomography scans have not identified any metastasis during postoperative evolution disease. We excised large surgical margin under local anesthesia. Pathological examination lesion diagnosed clear Our case just rare...
The aim of our study was to identify if there a relation between red cell distribution width, mean platelet volume, leukocyte count and thrombocyte at the time presentation hospital acute appendicitis.Acute appendicitis is one most common surgical emergencies. Misinterpretation symptoms findings in may lead removal normal appendix delayed diagnosis can result perforation peritonitis. Many studies tried delineate laboratory findings. Latest focused on components complete blood such as width...
Background: We aimed to compare the results of patients who underwent laparoscopic adrenalectomy (LA) for masses ≥6 cm versus <6 in diameter our tertiary referral university hospital. Materials and Methods: Three hundred thirty consecutive were divided into two groups according tumor size (≥6 diameter). Demographic variables, body mass index (BMI), lesion localization (right/left), diameter, pathological diagnosis surgical outcomes, including operation time, estimated blood loss (EBL),...
Objective: Neuroendocrine neoplasms of primary breast tumors are rare compared to locations, such as the respiratory system and gastrointestinal system, where they frequently observed.The diagnostic criteria for neuroendocrine have been changed since first description.Morphological immunohistochemical features helpful in their diagnosis, which vary due heterogeneous nature these tumors, highlighted this retrospective study.The purpose was determine specific histopathological that can...
Abstract Background: Previous prospective studies reported decreased false negative rates in patients presenting with T1-3/cN1 disease, the removal of 2 or more sentinel lymph nodes (SLNs), using combined technique for SLN biopsy (SLNB), and by targeted axillary dissection (TAD) initially clinically node-positive after neoadjuvant chemotherapy (NAC). The aim this study is to compare feasibility oncological safety TAD SLNB cN-positive/ycN0 breast cancer following NAC a study. Methods: This...
To compare the effectiveness of combined (indocyanine green [ICG]+ blue dye) tracing versus dye alone in guiding sentinel lymph node biopsy (SLNB) breast cancer. A total 112 female patients (mean ± SD age: 51.9 11.9 years) with clinically node-negative (cN0) early-stage cancer were evaluated based on SLN technique including methylene + ICG (n = 17), isosulfan 19) and 76). Mapping patterns each SLN, number nodes (TLNs) removed, metastatic hyperplastic nodes, detection rate analyzed for...
Abstract Background The omission of axillary lymph node dissection (ALND) remains controversial for patients with residual disease after neoadjuvant chemotherapy (NAC), regardless the burden. This study evaluated oncologic safety and factors associated outcomes in disease. These were treated solely sentinel biopsy (SLNB) or targeted (TAD), without ALND, NAC. Methods A joint analysis two different multicenter cohorts—the retrospective cohort registry MF18‐02 prospective observational MF18‐03...
The Bethesda System for Reporting Thyroid Cytopathology is one of the main classification systems thyroid nodules. It expects that 7% all fine needle aspiration biopsies will be reported as atypia or follicular lesions undetermined significance, and 5-15% these nodules are malignant. Our study a retrospective analysis variables may associated with outcome in patients indeterminate nodules.Patients who underwent thyroidectomy our institution between 2010 2014 were retrieved from institutional...
To date, the single-incision laparoscopic surgery (SILS) technique has been applied to a wide range of general surgical procedures; however, there are still scant data and debates on adrenal procedures. The aim this study was compare outcomes versus multiport adrenalectomy. patients were divided into 2 groups basis approach: SILS (group 1) 2). Patient demographics their perioperative postoperative results evaluated retrospectively from medical records. A total 80 included in study. There 44...
OBJECTIVES AND BACKGROUND: This study was designed to compare the usefulness of breast electrical conductivity measures performed in a surgical examination room against conventional screening modalities for identifying symptomatic lesions tissue.METHODS: A group 181 patients were examined with Ultrasonography (USG), Mammography (MG), Electrical Impedance Scanning (EIS) and followed-up 24 months clarify terms lesion tumour progression relationship.Tumour biopsy determined as an endpoint...
Obturator hernia (OH) is a rare condition with high rates of morbidity and mortality.While diagnosis difficult, surgery the definitive treatment.Intestinal obstruction most common symptom upon admission.In addition, small-bowel documented in more than half OH patients.Advanced age, intestinal obstruction, bowel perforation, comorbid diseases, clinical deterioration are risk factors for higher mortality.The aim present report was to document surgical management 3 female patients, each over 80...