- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Screening and Detection
- Surgical Simulation and Training
- Hernia repair and management
- Colorectal and Anal Carcinomas
- Gastrointestinal Tumor Research and Treatment
- Hip and Femur Fractures
- Metastasis and carcinoma case studies
- Iron Metabolism and Disorders
- Pancreatic and Hepatic Oncology Research
- Thyroid and Parathyroid Surgery
- Cancer Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- DNA Repair Mechanisms
- Stoma care and complications
- Minimally Invasive Surgical Techniques
- Thyroid Cancer Diagnosis and Treatment
- RNA modifications and cancer
- Pancreatitis Pathology and Treatment
- Anatomy and Medical Technology
- Enhanced Recovery After Surgery
- Intestinal and Peritoneal Adhesions
- Carcinogens and Genotoxicity Assessment
Koç University
2018-2024
Sağlık Bilimleri Üniversitesi
2022
Şişli Etfal Eğitim ve Araştırma Hastanesi
2022
National Research University Higher School of Economics
2018
Maastricht University Medical Centre
2018
Hôpital de la Timone
2018
State Scientific Center of Coloproctology
2018
Massachusetts General Hospital
2018
Pontificia Universidad Católica de Chile
2018
Aarhus University Hospital
2018
ABSTRACT Background The FLOT 4‐AIO trial established the docetaxel‐based regimen's superiority over epirubicin‐based triplet therapy in terms of survival rates and acceptable toxicity for locally advanced resectable gastric (LARGC). Yet, fewer than half patients achieved completion eight prescribed cycles. We proposed that administering all cycles form total neoadjuvant may improve downstaging. This study contrasted (FLOT x8) with standard 4+4) LARGC adenocarcinoma who underwent curative...
Abstract Inguinal and incisional hernias are the two most common types of caused by abdominal wall weakness defects in connective tissue. The structure extracellular matrix, mainly collagen metalloproteinases (MMPs), their regulators have been studied extensively found to play a significant role pathophysiology hernias. One MMPs, tissue inhibitor (TIMPs), bind MMPs inhibit its activity significantly shifting balance towards synthesis rather than degradation. Due importance metabolism,...
Breast cancer is the most common malignancy in women. Genetic risk factors associated with breast incidence have been identified.This study aimed at determining association of XRCC3 Thr241Met (rs861539), XRCC4 G(-1394) T (rs6869366) DNA repair and BAX G(-248) A (rs4645878), BCL2 C(-938) (rs2279115) apoptotic gene polymorphisms cancer.Genetic analysis was performed using peripheral blood samples. Gene were detected by polymerase chain reaction-restriction fragment length polymorphism...
To date, the single-incision laparoscopic surgery (SILS) technique has been applied to a wide range of general surgical procedures; however, there are still scant data and debates on adrenal procedures. The aim this study was compare outcomes versus multiport adrenalectomy. patients were divided into 2 groups basis approach: SILS (group 1) 2). Patient demographics their perioperative postoperative results evaluated retrospectively from medical records. A total 80 included in study. There 44...
Objective: Laparoscopic totally extraperitoneal inguinal hernia repair (TEP) surgery technique includes three key steps: reaching the preperitoneal space, reducing hernias, and placement of mesh. However, space can be complicated in patients with previous lower abdominal surgeries. This study aimed to assess feasibility laparoscopic TEP prostatectomies. Material Methods: Inguinal who underwent between January 2015 February 2021 at Koç University Faculty Medicine, Department General Surgery,...
Aim: Despite the increasing popularity of minimally invasive surgery (MIS) in recent years, its efficacy treating T4 colon cancer remains a subject ongoing debate.This study aimed to assess perioperative and oncological outcomes MIS for comparison with open (OP).Method: We conducted retrospective cohort analysis on 181 consecutive patients who underwent resection through either or OP between December 2014 September 2021.Converted were evaluated group according intention-to-treat...
Abstract Background While existing checklists and scoring systems assess open surgery TAPP (transabdominal preperitoneal procedure) surgeries, there is currently a lack of evaluation criteria dedicated checklist for TEP (totally extraperitoneal surgery. This study aims to develop comprehensive guiding the procedural steps minimally invasive establish system applicable resident training. Methods observational study, conducted at single center, involved 60 unedited videos performed by expert...
Objective: Metastases to the thyroid gland are rare. The most common tumors that metastasize kidney, lung, gastrointestinal tract, and breast tumors. from other primary cancer sites into a (defined as tumor-to-tumor metastases) even rarer.Methods: In this case report we present 10th published of lung metastasizing neoplasm.Results: A 53-year-old male patient had been diagnosed with metastatic non-small cell carcinoma 18 months previously (adenocarcinoma spread both lungs) was admitted...
Colorectal cancer is the third most common in Turkey. The current guidelines do not provide sufficient information to cover all aspects of management rectal cancer. Although treatment has been standardized terms basic principles neoadjuvant, surgical, and adjuvant therapy, uncertainties may lead significant differences clinical practice. In order clarify these uncertainties, a consensus program was constructed with participation physicians from Acıbadem Mehmet Ali Aydınlar Koç Universities....
Aim: To compare anal electrostimulation and extracorporeal magnetic stimulation in complex programs of conservative treatment incontinence.Method: The study included 59 people with incontinence.I group -22 patients (20 (90.9%) women), 50.9 AE 5.1 yearscomplex methods: electrostimulation, biofeedback tibial neuromodulation (TNM), II -37 (33 (89.2%) 51 4.4 stimulation, TNM.The method control was anorectal manometry.Results: Group Irest tone maximal squeezing pressure sphincters before were...
Abstract: Heald and Ryall introduced surgical techniques consisting of the complete removal mesorectum, which was named total mesorectal excision (TME) in 1980s. The main outcome that could be achieved treatment rectal cancer is obtaining a good quality besides enough harvested lymph nodes. TME reduces risk local recurrence improves survival patients with mid low disease. Many studies have indicated minimally invasive surgery provides faster postoperative recovery lower complication rate...