- COVID-19 Clinical Research Studies
- Oral health in cancer treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Diet, Metabolism, and Disease
- Artificial Intelligence in Healthcare and Education
- Nutrition and Health in Aging
- Eosinophilic Esophagitis
- Oral Health Pathology and Treatment
- Artificial Intelligence in Healthcare
- Pharmacological Effects and Toxicity Studies
- Respiratory and Cough-Related Research
- Frailty in Older Adults
- COVID-19 diagnosis using AI
- Long-Term Effects of COVID-19
- Asthma and respiratory diseases
- Oral microbiology and periodontitis research
- Urticaria and Related Conditions
- Obstructive Sleep Apnea Research
- Lung Cancer Research Studies
- Liver Disease Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Ureteral procedures and complications
- Abdominal Trauma and Injuries
- Body Composition Measurement Techniques
- Pharmacovigilance and Adverse Drug Reactions
Koç University
2020-2025
Istanbul Medipol University
2021
Turkish Society of Hematology
2021
Beykent University
2019
Istanbul University
2017
Abstract Objectives The pathogenesis of oral cavity cancers is complex. We tested the hypothesis that microbiota dysbiosis associated with cancer. Materials and methods Patients primary cancer who met inclusion exclusion criteria were included in study. Matching healthy individuals recruited as controls. Data on socio-demographic behavioral factors, self-reported periodontal measures habits, current dental status collected using a structured questionnaire chartings. In addition to health...
Rationale: Coronavirus disease (COVID-19) is an ongoing pandemic, in which obesity, hypertension, and diabetes have been linked to poor outcomes. Obstructive sleep apnea (OSA) associated with these conditions may influence the prognosis of adults COVID-19. Objectives: To determine effect OSA on clinical outcomes patients Methods: The current prospective observational study was conducted three hospitals Istanbul, Turkey from March 10 June 22, 2020. participants were categorized as high-risk...
Our objectives were to compare sleep health composite dimensions and chronotype in children adolescents with without type 1 diabetes (T1D) explore the relationship between glycemic variability T1D. The study comprised 84 participants T1D aged 6 18 years, age sex matched by controls. (SHC) was measured using actigraphy, diaries, self or parental reports. Sleep disturbance evaluated DSM-5 Level 2 Disorders Scale Short Form. Chronotype determined Children's Questionnaire. median total SHC score...
Abstract Background Sarcopenia is a syndrome that cause falls, fractures, and morbidity in geriatric patients. Early diagnosis of sarcopenia important as it known muscle functions can improve with early intervention. We aimed to investigate whether urinary amino acid levels could serve biomarkers sarcopenia. Methods The study included ninety-one patients aged 45–65 who visited our outpatient clinic. underwent physical examinations, blood tests sixteen distinct were analyzed. Anthropometric...
Acute kidney injury (AKI) in COVID-19 patients is associated with poor prognosis. However, the incidence, risk factors and potential outcomes of AKI hospitalized are not well studied. This a retrospective cohort study conducted two major university hospitals. Electronic health records patients, 18 years or older, between 13 April 1 June 2020 confirmed were reviewed. We described incidence for development patients. Furthermore, we investigated effects on length hospital intensive care unit...
Background: The consumption of sweetened beverages is associated with increased risk metabolic syndrome, cardiovascular disease, and type 2 diabetes mellitus. Objective: We hypothesized that the effects fructose in sugary might be modulated by speed ingestion addition to overall amount. Design: Thirty healthy subjects free any disease medication were recruited into two groups. After overnight fasting, group 1 drank 500 mL apple juice over an hour drinking 125 every 15 min, while 5 min. Blood...
Background: Trastuzumab prolonged the overall survival in patients with advanced gastric cancer human epidermal growth factor receptor 2 (HER2) overexpression combination chemotherapy. In this phase II open-label prospective study, tolerability and safety of trastuzumab chemotherapy, chemoradiotherapy for curatively resected HER2-positive carcinoma was investigated. Methods: The gastric, or gastroesophageal junction adenocarcinoma, after gastrectomy plus D2 dissection, were included. They...
We evaluated the relationship between erectile dysfunction (ED) and IL-6 levels in males with COVID-19. The study included 80 male patients aged 30-45 years who were hospitalised due to International Index of Erectile Function (IIEF-5) questionnaire was used assess function. IIEF-5 re-administered at a 3-month control visit after discharge, change score from baseline recorded. divided into three groups according 3 months as Group 1 (severe ED), 2 (moderate ED) (no two level time admission A...
(1) Background: The Berlin questionnaire (BQ) is a widely used survey to predict obstructive sleep apnea (OSA). Considering the confounding effect of obesity and hypertension on clinical course COVID-19, we have recently developed modified BQ (mBQ) based subscales snoring intensity/frequency, witnessed apneas morning/daytime tiredness, demonstrated that patients with high-risk OSA had worse outcomes during COVID-19 pandemic. In current study, aimed validate mBQ in adults history infection....
Abstract Background Although chronic urticaria (CU) is a common and primarily affects females, there little data on how pregnancy interacts with the disease. Objective To analyse treatment use by CU patients before, during after as well outcomes of pregnancy. Methods PREG‐CU an international, multicentre study Urticaria Centers Reference Excellence network. Data were collected via 47‐item‐questionnaire completed who became pregnant their disease course. Results Questionnaires from 288 13...
OBJECTIVES:There is no validated questionnaire in Turkish to assess asthma knowledge.In this study, we aimed evaluate the reliability and validity of version Asthma Self-Management Knowledge Questionnaire (AKQ) among asthmatic adults. MATERIAL AND METHODS:The AKQ was translated into by two medical-text translators, followed back translation final review clinicians with experience management.The then applied 202 adult patients, additional demographic clinical features patients were collected...
The use of the second trimester alpha-fetoprotein (AFP) along with first pregnancy-associated plasma protein-A (PAPP-A) has been found to be useful in estimation unfavourable pregnancy outcome. Our aim this study was determine relationship between maternal PAPP-A and b-hCG AFP concentrations spontaneous preterm birth (sPTB). This prospective cohort included 372 singleton pregnancies PAPP-A, levels trimester, which were converted multiples median (MoM). predictive ability AFP-to-PAPP-A...
Introduction: Pilocytic astrocytoma (PA) is one of the most common primary intracranial neoplasms in childhood with an overall favorable prognosis. Despite decades experience, there are still diagnostic and treatment challenges unresolved issues regarding risk factors associated recurrence, often due to conclusions publications limited data. We analyzed 499 patients PA diagnosed a single institution over 30 years order provide answers some issues. Materials Methods: identified pilocytic...
Machine learning (ML) and artificial intelligence (AI) techniques are gaining popularity as effective tools for coronavirus disease of 2019 (COVID-19) research. These strategies can be used in diagnosis, prognosis, therapy, public health management. Bibliometric analysis quantifies the quality impact scholarly publications. ML COVID-19 research is focus this bibliometric analysis.
25-hydroxy VD insufficiency is known in children undergoing LT but the serial post-transplant course and supplementation modalities peri-transplant period are lacking. We aimed to determine pre-VD status following elucidate its relationship with outcome parameters such as infection survival.Pre- post-VD levels were monitored parallel interventions adjust patients. was categorized circulating <30-21 ng/ml (insufficiency), 20-10 (deficiency), <10 (severe deficiency). Patients received stoss...
Abstract Objectives In many diseases, immature platelet fraction (IPF%) is related to coagulopathy and poor outcome. This study aimed investigate the predictive value of IPF% for severity pneumonia in patients with Coronavirus Disease 2019 (COVID-19). Methods A total 154 COVID‐19 infections were included. The divided into two groups according (severe non-severe) regarding their oxygen demand. Results Given laboratory parameters, median was significantly higher severe group (11.9 vs. 3.9%,...
OBJECTIVES:A multicenter trial was designed to validate the "Assessment Tools for Asthma (ATA)" questionnaire, a newly developed which evaluates both asthma control and risk factors associated with single instrument. MATERIALS AND METHODS:This cross-sectional study involved 810 cases from 14 clinics in 9 Turkish cities.The ATA questionnaire Control Test (ACT) were administered.The Visual Analog Scale (VAS) used evaluate status of 100 randomized cases.ATA is an eight-item...
BACKGROUND: Various tools have been created to measure physical function during intensive care unit (ICU) stay and after ICU discharge, but those not validated in coronavirus 2019 (COVID-19) patients. There is a need for reliable, valid feasible tool define the rehabilitation needs of post-ICU COVID-19 patients entering acute wards then clinics. OBJECTIVE: This study aims investigate validity, inter-rater reliability feasibility Chelsea Physical Assessment Tool (CPAx) assessing functional...