A5013806660- COVID-19 Clinical Research Studies
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Antibiotics Pharmacokinetics and Efficacy
- Tuberculosis Research and Epidemiology
- Cardiac electrophysiology and arrhythmias
- Infectious Diseases and Tuberculosis
- Antifungal resistance and susceptibility
- Drug-Induced Ocular Toxicity
- Influenza Virus Research Studies
- Mycobacterium research and diagnosis
- Vaccine Coverage and Hesitancy
- COVID-19 and Mental Health
- COVID-19 epidemiological studies
- Long-Term Effects of COVID-19
- HIV-related health complications and treatments
- Autoimmune Bullous Skin Diseases
- Vibrio bacteria research studies
- Polyomavirus and related diseases
- Dermatological and COVID-19 studies
- Actinomycetales infections and treatment
- Vasculitis and related conditions
- IgG4-Related and Inflammatory Diseases
- Nosocomial Infections in ICU
Koç University
2019-2024
Istanbul Medipol University
2024
Sema Hospital
2016-2019
Istanbul University
2007-2014
We describe the molecular characteristics of colistin resistance and its impact on patient mortality. A prospective cohort study was performed in seven different Turkish hospitals. The genotype each isolate determined by MLST repetitive extragenic palindromic PCR (rep-PCR). Alterations mgrB were detected sequencing. Upregulation pmrCAB, phoQ pmrK quantified RT–PCR. mcr-1 genes encoding OXA-48, NDM-1 KPC amplified PCR. total 115 patients diagnosed with colistin-resistant K. pneumoniae...
Rationale: Coronavirus disease (COVID-19) is an ongoing pandemic, in which obesity, hypertension, and diabetes have been linked to poor outcomes. Obstructive sleep apnea (OSA) associated with these conditions may influence the prognosis of adults COVID-19. Objectives: To determine effect OSA on clinical outcomes patients Methods: The current prospective observational study was conducted three hospitals Istanbul, Turkey from March 10 June 22, 2020. participants were categorized as high-risk...
We aimed to describe the increased rate of Acinetobacter baumannii infections during COVID-19 pandemic and define its significance within last five years. This study was performed in a tertiary hospital with 280 beds included all patients infected A. intensive care unit between January 1, 2018, June 30, 2022. baumannii-infected 27 months before were included. Pulsed-field gel electrophoresis assess clonal relatedness. The infection control measures specified based on findings targeted...
BackgroundInfection with the influenza A virus can cause severe disease and mortality. The effect of different subtypes on morbidity mortality is not yet known in Turkey. aim this study was to describe predictors fatality related infection among hospitalized patients Istanbul during 2015–2016 season, detail differences between infections caused by H3N2 H1N1.MethodsThis a multicenter performed Respiratory Infections Study Group Turkish Society Clinical Microbiology Infectious Diseases...
Crimean-Congo haemorrhagic fever (CCHF) is a severe disease with case fatality of 2.8 to 80 %. A patient dwelling in an endemic region for CCHF was admitted preceding bleeding diathesis and pancytopenia. Despite no history tick exposure, highly suspected. With oral ribavirin therapy, clinical laboratory improvements were obtained. The diagnosis confirmed by detection IgM antibody virus positive RT-PCR. Although the main pathogenesis infection not elucidated yet, haemophagocytosis, symptom...
Hypersensitivity reactions has been reported with COVID-19 vaccines. Acute eosinophilic pneumonia not yet after Sinovac/CoronaVac vaccine. A 73-year-old woman presented maculopapular rash, cough and dyspnea following injection. The complete blood count (CBC) indicated eosinophilia further evaluation of the CT bronchoscopy confirmed a diagnosis acute pneumonia. After methylprednisolone therapy, her rash resolved marked improvement dyspnea. She is still on treatment follow up period, we plan...
Background Cefiderocol is generally active against carbapenem-resistant Klebsiella spp. (CRK) with higher MICs metallo-beta-lactamase producers. There a variation in cefiderocol interpretive criteria determined by EUCAST and CLSI. Our objective was to test CRK isolates compare susceptibilities using CLSI criteria.Methods A unique collection (n = 254) of mainly OXA-48-like- or NDM-producing bloodstream were tested disc diffusion (Mast Diagnostics, UK). Beta-lactam resistance genes multilocus...
Background: Cryptosporidiosis has been reported in both immunocompetent and immunocompromised patients from over 40 countries six continents. Objectives: This study was carried out to determine the prevalence of Cryptosporidium spp. by methods modified acid fast staining, ELISA Cassette Kit, also compare three methods. Methods: The different age groups admitted Bitlis state hospital between June 23, 2011 January 13, 2015 were enrolled. group composed 300 volunteer control 100 volunteers with...
Background: We aimed to detect the risk factors for SARS-CoV-2 infection among healthcare workers (HCWs) in 2020 before vaccination era. Methods: surveyed HCWs a hospital through screening antibody levels and detection of viral RNA by RT-PCR between May December 2020. Occupational non-occupational potential predictors disease were included this study. Results: Among 1925 personnel hospital, 1732 study with response rate 90%. The overall was 16.3% at end 2020, vaccinations started. In...
Highly active antiretroviral therapy (HAART) has markedly decreased human immunodeficiency virus- (HIV-) related mortality and the incidence of opportunistic infections. The dramatic reduction in HIV-1 RNA increase CD4 lymphocyte count mean a recovery immune function. This restoration function may be associated with paradoxical deterioration subclinical infections some patients, condition called reconstitution inflammatory syndrome (IRIS). IRIS, "paradoxical" response to either previously...
Abstract Objectives In many diseases, immature platelet fraction (IPF%) is related to coagulopathy and poor outcome. This study aimed investigate the predictive value of IPF% for severity pneumonia in patients with Coronavirus Disease 2019 (COVID-19). Methods A total 154 COVID‐19 infections were included. The divided into two groups according (severe non-severe) regarding their oxygen demand. Results Given laboratory parameters, median was significantly higher severe group (11.9 vs. 3.9%,...
Data in the literature on use of ceftazidime-avibactam (CAZ-AVI) carbapenem-resistant Klebsiella pneumoniae bloodstream infections (CRKP-BSIs) are limited especially OXA-48 (Oxacillinase-48) predominant regions. Our study aimed to evaluate effect CAZ-AVI outcomes CRKP-BSIs Turkey, where is endemic. A multicenter retrospective observational was conducted between January 2017 and September 2021. The effects clinical treatment characteristics 30-day mortality relapse were analyzed. Predictors...
<title>Abstract</title> Background. Experience of ceftazidime-avibactam (CAZ-AVI) use in OXA-48 producing <italic>K. pneumoniae</italic> bloodstream infections (OXA-48-Kp BSIs) is limited. We aimed to describe the clinical outcomes OXA-48-Kp BSIs treated with CAZ-AVI hospital settings, where OXA-48-producing endemic. Methods. A multicenter retrospective observational study was conducted between January 2017 and September 2021. The aim data that affects outcome, 30-day mortality relapse....
Background/Objectives: Studies attempting to predict the development of severe respiratory failure in patients with a COVID-19 infection using machine learning algorithms have yielded different results due differences variable selection. We aimed failure, defined as need for high-flow oxygen support, continuous positive airway pressure, or mechanical ventilation, COVID-19, identify most important variables achieving this prediction. Methods: This retrospective, cross-sectional study included...
Actinomyces species may lead to slowly progressive infection of almost any site once mucosal breakdown exists; hence, it has the name "great pretender." Its diagnosis be unthinkable unless proper cultures/histologies are taken. We describe a patient with lumbar spondylodiscitis and epidural abscess. This is an exceptional another disease by actinomycosis.